Johannes Larsch

First whole-brain recording of social sound processing in a vertebrate. Surprises start in the hindbrain; thalamus gates conspecific calls; male and female brains diverge downstream. Work by @joerghenninger.bsky.social, @mh123.bsky.social sky.social and team. www.biorxiv.org/content/10.6...

Plastic landmark anchoring in zebrafish compass neurons Nature - Using two-photon microscopy with a panoramic virtual reality setup, how head direction cells in larval zebrafish integrate visual landmarks and optic flow to track orientation is revealed.

1/6: New publication from the lab: “Plastic landmark anchoring in zebrafish compass neurons” by Ryosuke Tanaka (@ryosuketanaka.bsky.social) and Ruben is available here:
rdcu.be/eX1L4

Deadline for this post-doc position in my lab extended to Jan 11th!

Exciting new #Zebrafish research from the #WeinsteinLab, led by Jong Park!
“Specialized gas-exchange endothelium of the zebrafish gill” —

www.biorxiv.org/content/10.6...

Amazing to see red blood cells moving through the gills! Don’t forget to check out the supplemental movies ;-)

Slow-mo video of zebrafish mating. Credit to
@zebrafish007.bsky.social. #ZebrafishZunday 🧪

A GPCR signaling pathway in insect odor detection Odor detection differs fundamentally in vertebrates, which use G protein-coupled receptors (GPCRs), and insects, which employ ion channels. Here, we report the first evidence for a GPCR defining tunin...

Having personally sworn for years that insects don’t use GPCRs for odour detection, Suguru Takagi (@sugurutakagi.bsky.social) discovers that, in fact, they sometimes do …

www.biorxiv.org/content/10.1...

“Blame your parents if you can’t pay enough attention." At least when you are a zebrafish! Our new study on attentional switching together with Kumaresh Krishnan, @paulapflitsch.bsky.social , @zwitscherarmin.bsky.social and Florian Engert is out in Science Advances:
doi.org/10.1126/scia...

The final version of our paper on how ants and possibly other insects use a crazy mechanism involving extensive transcriptional interference to regulate odorant receptor expression is now open access in my favorite journal, @currentbiology.bsky.social

authors.elsevier.com/sd/article/S...

PhD Fellowships in Life Sciences: a competition open to future doctoral students. Apply now for FBM PhD Fellowships in Life Sciences – join one of the Faculty’s leading laboratories.

Apply now for FBM #PhD #Fellowships in #Life #Sciences – join one of the Faculty’s leading laboratories.

🚨 Application deadline for fellowships: October 6, 2025.
➡️ www.unil.ch/news/en/1756...

@unil.bsky.social @dmf-unil.bsky.social @dee-unil.bsky.social @dib-unil.bsky.social #fbm #unil

Hierarchical processing of sensory information across topographically organized thalamocortical-like circuits in the zebrafish brain Thalamocortical projections contribute to the spatial organization and functional hierarchies of the mammalian cortex. Primary sensory cortices receive topographically segregated information from firs...

Check out this exciting study led by Anh-Tuan Trinh from our lab, where we investigated how thalamocortical-like circuits in the zebrafish pallium receive, represent, and integrate sensory information:
🔗 doi.org/10.1101/2025...

BonnBrain 2026 is a go!
March 23–25, Bonn (DZNE, Bonn, Germany).
Apply now: www.bonnbrain.de
Limited slots. Presentations (posters/talks) selected from submitted abstracts.

Keynotes & invited speakers 👇

Now published @natecoevo.nature.com with @annika-nichols.bsky.social, our latest on the evolution of 𝘴𝘭𝘦𝘦𝘱 across 𝟲𝟬 𝘀𝗽𝗲𝗰𝗶𝗲𝘀 of cichlid fishes! doi.org/10.1038/s415...
with members of the @schierlab.bsky.social and Salzburger labs, as well as the burgeoning Shafer lab @uoftcellsysbiol.bsky.social

Jim was an incredibly gifted teacher. Still remember his fundamentals in Neuroscience. Also, great, dry sense of humor.

Supraspinal commands have a modular organization that is behavioral context specific Lau et al. use calcium imaging and statistical modeling to comprehensively survey reticulospinal activity during diverse locomotor behaviors. They find that a small set of functional modules act combi...

Latest from the lab. Beautiful work from Joanna Lau and a fantastic collaboration with James Fitzgerald.

www.cell.com/current-biol...

Can't wait to read this preprint from Misha Ahrens and team. Calcium imaging in larval zebrafish, in every cell in the body! Amazing.

www.biorxiv.org/content/10.1...

Transcriptional Interference Gates Monogenic Odorant Receptor Expression in Ants Communication is crucial to social life, and in ants, it is mediated primarily through olfaction. Ants have more odorant receptor (OR) genes than any other group of insects, generated through tandem d...

If you’re interested in ants, olfaction, gene regulation, or all of the above, here’s a new preprint from the lab for you. It describes an unorthodox mechanism of transcriptional interference by which ant olfactory sensory neurons produce a single functional receptor.
www.biorxiv.org/content/10.1...

ALT text: A UMAP representation of a single cell RNAseq dataset from the Drosophila ventral nerve cord as well as images of the Drosophila nerve cord connectome and different stages of fly development.

Neuronal diversity is written in transcriptional codes 🧬. But what is the logic of these codes that define cell types and wiring patterns?
To find out we built a #scRNAseq developmental atlas of the Drosophila nerve cord and linked it to the #connectome 🪰🧠
#preprint thread ⬇️1/8

RFK Jr. in interview with Scripps News: ‘Trusting the experts is not science’ HHS Secretary RFK Jr. sat down with Scripps News for a wide-ranging interview, discussing mRNA vaccine funding policy changes and a recent shooting at the Centers for Disease Control and Prevention.

1. "'Trusting the experts is not a feature of either a science or democracy," Kennedy said."

It's literally a vital feature of both science and of representative democracy.

I've written a fair bit about trust in expertise as a vital mechanism in the collective epistemology of science.

A stylised hand holds a smartphone from which colourful digital pages flow outward, surrounded by icons of books, screens, and learning materials on a dark blue and purple background.

💡 Whether you’re a new student, a lab leader or a decision-maker at an institutional level, you can now find free tools and guidance all in one place on our new Learning Resources page.

With everything in the thread below and more, get learning today!
buff.ly/sIpX5gU

Binocular integration of prey stimuli in the zebrafish visual system Most animals with two eyes combine the inputs to achieve binocular vision, which can serve numerous functions and is particularly useful in hunting pr…

Latest from my lab: we identify and characterize the function of binocular neurons zebrafish larvae use to hunt prey; sciencedirect.com/science/arti.... Congrats to Richard Tian, Gewei Yan and Tommy Lam @tkclam.bsky.social!

How does the brain work in natural scenarios, in multi-animal societies of wild animals? 🧠 🧪 🦇

doi.org/10.1126/scie...

(1/n)

🚨Very happy that my PhD work is now out in @nature.com!

We discovered that evolution, by acting in the midbrain, shifted the threshold to escape in Peromyscus mice, to fine-tune defensive strategies in different environments

www.nature.com/articles/s41...

This was a truly collaborative effort! 🧵⬇️

Great job opportunity at The Center for Integrative Genomics, Lausanne University, Switzerland unil.ch/cig/en/home....
For a tenure-track Assistant Professor position. More details for how to apply are here nature.com/naturecareer...

CIG- UNIL

Become our colleague! Tenure-track Assistant Professor position at The Center for Integrative Genomics, University of Lausanne, Switzerland. unil.ch/cig/en/home....
More details for how to apply are here:
www.nature.com/naturecareer...

Faculty Position in Neuroscience The School of Life Sciences at EPFL invites applications for a Tenure Track Assistant Professor position in Neuroscience. At EPFL researchers develop and apply innovative technologies to understand br...

We are looking for a new neuroscience colleague at the tenure track assistant professor level! All details below! 🧠🔥 All details here: www.epfl.ch/about/workin...

Congratulations Silvana! 🎉

Congrats to @stednitz.bsky.social and Andrew Lesak on their @currentbiology.bsky.social paper! They use HMM to identify two interaction states in #zebrafish: one visual for long-range interactions and one lateral line for quick, close interactions.

Free link: authors.elsevier.com/a/1lCYh3QW8S...

Heart disease is the world’s leading killer, and tackling it demands decoding the multi-gene networks driving disease progression 🫀

Learn how researchers used Medaka fish plus high-throughput heartbeat imaging to build a biomarker toolkit for early screening.

www.nature.com/articles/s41...

Correlative light and electron microscopy reveals the fine circuit structure underlying evidence accumulation in larval zebrafish Accumulating information is a critical component of most circuit computations in the brain across species, yet its precise implementation at the synaptic level remains poorly understood. Dissecting su...

We are proud to present our new preprint “Correlative light and electron microscopy reveals the fine circuit structure underlying evidence accumulation in larval zebrafish”, just posted on bioRxiv (www.biorxiv.org/content/10.1...). (1/10)