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David Barack

@dlbarack

Philosopher and neuroscientist | Studying inquiry and foraging | Conceptual and theoretical foundations of cognition | #T1D

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09.08.2023
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Latest posts by David Barack @dlbarack

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Compact deep neural network models of the visual cortex Nature - Parsimonious deep neural network models can be used for prediction of visual neuron responses.

DNN models of the brain are getting bigger. Are we replacing one complicated system in vivo with another in silico?

In new work, we seek the *smallest* DNN models of visual cortex, balancing prediction with parsimony.

It turns out these compact models are surprisingly small!

rdcu.be/e5H8G

26.02.2026 22:32 πŸ‘ 103 πŸ” 37 πŸ’¬ 3 πŸ“Œ 3

Can electrical microstimulation be used to steer cortical population activity on- and off-manifold? Our new preprint says yes β€” using data-driven control in macaque PFC. Joint work with @gbarzon.bsky.social, Anandita De, Isaac Moran, Conner Carnahan, and Luca Mazzucato.

05.03.2026 00:05 πŸ‘ 53 πŸ” 15 πŸ’¬ 1 πŸ“Œ 1

From the top of my head, here some recent ones:

"Two views on the cognitive brain" by @johnwkrakauer.bsky.social, @dlbarack.bsky.social

"Reconstructing computational system dynamics from neural data with recurrent neural networks" by @durstewitzlab.bsky.social et al

1/3

01.03.2026 14:28 πŸ‘ 30 πŸ” 7 πŸ’¬ 1 πŸ“Œ 0

After several years of work, my lab is starting to put out our first papers on learning in a unicellular organism (Stentor coeruleus).

Here we show evidence for a form of associative learning in Stentor:
www.biorxiv.org/content/10.6...

26.02.2026 11:39 πŸ‘ 176 πŸ” 57 πŸ’¬ 5 πŸ“Œ 7
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Vectorized instructive signals in cortical dendrites - Nature Mice learning a neurofeedback brain–computer interface task show neuron-specific teaching signals in cortical dendrites, consistent with a vectorized solution for credit assignment in the brain.

This paper on how the brain may do gradient descent is very cool: www.nature.com/articles/s41...

26.02.2026 03:02 πŸ‘ 146 πŸ” 44 πŸ’¬ 3 πŸ“Œ 2
OSF

A new preprint, co-authored with @johnwkrakauer.bsky.social:

The Deliberation Taboo

Cognitive science is, nominally, the science of thinking. We argue that the field has no theory of what thinking is and, even worse, that the topic has largely dropped out of focus. 1/

osf.io/preprints/ps...

24.02.2026 13:53 πŸ‘ 136 πŸ” 52 πŸ’¬ 4 πŸ“Œ 11
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Interdisciplinarity Through Research Collaboration & Philosophy and Neuroscience Mentorship Program applications are due 2.28.26. Visit our website for more information.

15.12.2025 18:29 πŸ‘ 12 πŸ” 8 πŸ’¬ 0 πŸ“Œ 4
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A New Function for Episodic Memory? Muhammad Ali Khalidi (Graduate Center, City University of New York)

What is the function of episodic memory? Today at The Memory Palace, Muhammad Ali Khalidi (CUNY) shares ideas on the functions of episodic memory, and how this capacity might link individual cognition and joint agency.

open.substack.com/pub/thememor...

17.02.2026 16:38 πŸ‘ 8 πŸ” 2 πŸ’¬ 0 πŸ“Œ 1

Hierarchy in neuronal representations of multiple tasks in prefrontal cortex https://www.biorxiv.org/content/10.64898/2026.02.10.705211v1

12.02.2026 23:15 πŸ‘ 12 πŸ” 3 πŸ’¬ 0 πŸ“Œ 1
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ITRC project benefits for early career researchers: πŸ“„ Results in 2 publications (academic and public-facing), πŸŽ“ training on translating work for a popular audience, πŸ’° project funding, πŸ’ΌSPAN2027 conference presentation, 🀝 hands on interdisciplinary research + more! πŸ… @danafoundation.bsky.social 🧠

11.02.2026 20:56 πŸ‘ 5 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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Very happy to see "Pretending not to know reveals a capacity for model-based self-simulation", a collaboration with @chazfirestone.bsky.social and @ianbphillips.bsky.social, out in Psych. Science!

journals.sagepub.com/doi/10.1177...

🧡

10.02.2026 17:25 πŸ‘ 66 πŸ” 29 πŸ’¬ 1 πŸ“Œ 3
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Our paper is out in @natneuro.nature.com!

www.nature.com/articles/s41...

We develop a geometric theory of how neural populations support generalization across many tasks.

@zuckermanbrain.bsky.social
@flatironinstitute.org
@kempnerinstitute.bsky.social

1/14

10.02.2026 15:56 πŸ‘ 273 πŸ” 100 πŸ’¬ 7 πŸ“Œ 1
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Prefrontal neural geometry of learned cues guides motivated behaviours - Nature The dorsomedial prefrontal cortex encodes the value, salience and valence of learned stimuli along distinct neural dimensions, and the geometry of these representations shapes motivated behaviours in ...

Can you easily distinguish between value, valence, and salience?

Probably not, but the prefrontal cortex of mice seems to achieve this by creating a sort of multidimensional orthogonal neural space, where each dimension corresponds to one of these subjective elements

www.nature.com/articles/s41...

09.02.2026 13:31 πŸ‘ 46 πŸ” 20 πŸ’¬ 1 πŸ“Œ 0

Congrats!

07.02.2026 13:53 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Promotional poster for the XIV Workshop on Philosophy of Biology and Cognitive Sciences. The poster features a dark green background with stylized yellow and red floral illustrations around the edges. Large yellow text announces the workshop title. The event will take place 18–19 June at UNED, Edificio de Humanidades, Paseo de la Senda del Rey 7, Madrid. The keynote speakers listed are Alejandro FΓ‘bregas-Tejeda (KU Leuven), Enara GarcΓ­a (SDU), and JosΓ© Antonio PΓ©rez-Escobar (UNED). The poster highlights a Call for Abstracts (CfA) with an extended deadline of 1st February. Contact information is provided at xivpbcs@gmail.com

Promotional poster for the XIV Workshop on Philosophy of Biology and Cognitive Sciences. The poster features a dark green background with stylized yellow and red floral illustrations around the edges. Large yellow text announces the workshop title. The event will take place 18–19 June at UNED, Edificio de Humanidades, Paseo de la Senda del Rey 7, Madrid. The keynote speakers listed are Alejandro FΓ‘bregas-Tejeda (KU Leuven), Enara GarcΓ­a (SDU), and JosΓ© Antonio PΓ©rez-Escobar (UNED). The poster highlights a Call for Abstracts (CfA) with an extended deadline of 1st February. Contact information is provided at xivpbcs@gmail.com

Final days to submit an abstract to #PBCS2026! If you are an early-career scholar looking for a supportive environment to discuss your work & meet international peers, consider applying! Another plus this year: The workshop will be in Madrid! sites.google.com/view/xivpbcs... #HPbio #philsci #philsky

31.01.2026 15:05 πŸ‘ 36 πŸ” 17 πŸ’¬ 0 πŸ“Œ 0

every epstein file drop underscores how elite power operates through shared socio-economic networks, regardless of people's ideological differences, populist posturing, or public feuds

30.01.2026 23:58 πŸ‘ 30045 πŸ” 6539 πŸ’¬ 388 πŸ“Œ 308

Cool paper

28.01.2026 23:54 πŸ‘ 7 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Attention-like regulation of theta sweeps in the brain's spatial navigation circuit Spatial attention supports navigation by prioritizing information from selected locations. A candidate neural mechanism is provided by theta-paced sweeps in grid- and place-cell population activity, which sample nearby space in a left-right-alternating pattern coordinated by parasubicular direction signals. During exploration, this alternation promotes uniform spatial coverage, but whether sweeps can be flexibly tuned to locations of particular interest remains unclear. Using large-scale Neuropixels recordings in freely-behaving rats, we show that sweeps and direction signals are rapidly and dynamically modulated: they track moving targets during pursuit, precede orienting responses during immobility, and reverse during backward locomotion β€” without prior spatial learning. Similar modulation occurs during REM sleep. Canonical head-direction signals remain head-aligned. These findings identify sweeps as a flexible, attention-like mechanism for selectively sampling allocentric cognitive maps. ### Competing Interest Statement The authors have declared no competing interest. European Research Council, Synergy Grant 951319 (EIM) The Research Council of Norway, Centre of Neural Computation 223262 (EIM, MBM), Centre for Algorithms in the Cortex 332640 (EIM, MBM), National Infrastructure grant (NORBRAIN, 295721 and 350201) The Kavli Foundation, https://ror.org/00kztt736 Ministry of Science and Education, Norway (EIM, MBM) Faculty of Medicine and Health Sciences; NTNU, Norway (AZV)

The hippocampal map has its own attentional control signal!
Our new study reveals that theta #sweeps can be instantly biased towards behaviourally relevant locations. See πŸ“Ή in post 4/6 and preprint here πŸ‘‰
www.biorxiv.org/content/10.6...
🧡(1/6)

28.01.2026 10:03 πŸ‘ 183 πŸ” 62 πŸ’¬ 4 πŸ“Œ 10
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Episodic memory facilitates flexible decision-making via access to detailed events - Nature Human Behaviour Nicholas and Mattar found that people use episodic memory to make decisions when it is unclear what will be needed in the future. These findings reveal how the rich representational capacity of episod...

Our experiences have countless details, and it can be hard to know which matter.

How can we behave effectively in the future when, right now, we don't know what we'll need?

Out today in @nathumbehav.nature.com , @marcelomattar.bsky.social and I find that people solve this by using episodic memory.

23.01.2026 13:18 πŸ‘ 130 πŸ” 49 πŸ’¬ 7 πŸ“Œ 2
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*Multi-region computations in the brain*
When two regions are better than one...
doi.org/10.1016/j.ne...
#neuroskyence

23.01.2026 18:14 πŸ‘ 50 πŸ” 14 πŸ’¬ 2 πŸ“Œ 0

due date is about a month away πŸ‘€

25.01.2026 02:26 πŸ‘ 5 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0

Alex Pretti was a colleague at the VA. We hired him to recruit for our trial. He became an ICU nurse- I lover working with him. He was a good kind person who lived to help and these fuckers executed him.

White. Hot. Rage.

24.01.2026 19:31 πŸ‘ 60627 πŸ” 18876 πŸ’¬ 1404 πŸ“Œ 741
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Aaaand we're back!!

Two Postdocs in Philosophy of Mind (one ot two years), Centre for Philosophical Psychology, University of Antwerp

- to work with me!

Deadline: March 20, 2026

More info on PhilJobs

22.01.2026 16:42 πŸ‘ 55 πŸ” 35 πŸ’¬ 1 πŸ“Œ 3
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What kinds of cognitions are possible? Are there discrete classes of cognition? Here's our new paper with @brigan.bsky.social @jordiplam.bsky.social @mitibennett.bsky.social @mkhochb.bsky.social and @drmichaellevin.bsky.social arxiv.org/abs/2601.12837 We explore basal, neural and human-AI spaces.

21.01.2026 10:06 πŸ‘ 66 πŸ” 25 πŸ’¬ 1 πŸ“Œ 0

This is wild

19.01.2026 05:09 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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🧠 CALL FOR SYMPOSIA ABSTRACTS 🌴 SPAN is now accepting abstracts for a special session at the PSA. Put a group and a topic together and submit your idea via email by March 1st πŸ₯³

15.01.2026 00:25 πŸ‘ 8 πŸ” 3 πŸ’¬ 0 πŸ“Œ 2
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The 52nd annual meeting of the SPP will be at JHU, June 17-20

πŸ“£ Submit your work by January 16! πŸ“£

09.01.2026 14:09 πŸ‘ 31 πŸ” 15 πŸ’¬ 1 πŸ“Œ 1

like are you fucking kidding me

09.01.2026 05:11 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0