Denise Selegato

Comprehensive GC–MS/MS Quantification of Gut Microbiota–Derived Metabolites Across Intestinal and Systemic Tissues | LCGC International To enable robust investigation of microbiota–host metabolic interactions, a targeted gas chromatography–tandem mass spectrometry (GC–MS/MS) method was developed and validated by a research group at the European Molecular Biology Laboratory (Heidelberg, Germany) for the simultaneous quantification of 120 chemically diverse gut microbiota–derived metabolites across multiple biological matrices. LCGC International recently spoke to Nikita Denisov and Michael Zimmermann, two of the authors of a paper resulting from this work.

LCGC International recently spoke to Nikita Denisov and Michael Zimmermann, two of the authors of the our recently published paper that enables robust investigation of microbiota–host metabolic interactions.

You can check the interview here:
www.chromatographyonline.com/view/compreh...

Development of a GC-MS/MS method to quantify 120 gut microbiota-derived metabolites The gut microbiota produces metabolites that are important for host physiology and have critical roles in the development of diseases, such as metabolic disorders, cardiovascular diseases, and cancer....

📍Paper alert 📍

Our new preprint is available on: chemrxiv.org/engage/chemr...

Here, we show the development of a GC-MS/MS method for the quantification of 120 compounds produced by gut bacteria, including SCFA, indols, organic acids, and amino acid derivatives.

Vitamin B2 Production by Vaginal Lactobacilli Promotes Symbiosis The human vaginal microbiome, particularly with lactobacilli as the main inhabitants, plays a key role in maintaining women's health. While lactic acid-mediated pathogen exclusion is well known, broad...

We are very happy to share a new preprint 🎉

Congratulations to everyone involved!
@carolinedricot.bsky.social, @denisemselegato.bsky.social, @sarahlebeer.bsky.social and co.

www.biorxiv.org/content/10.1...

📍Preprint Alert 📍

📍New Paper Alert 📍

📍Preprint Alert 📍

MIX-MB (Minimum Information about Xenobiotics-Microbiome Biotransformation) - Community Consensus Survey This survey aims to establish the Minimum Information about Xenobiotics-Microbiome Biotransformation (MIX-MB) reporting standards. As we move toward an era of AI-driven discovery, the structural and f...

🚨 Do you work on microbial-mediated biotransformation of chemical compounds?
🧪 We would value your input to help us develop a standardized reporting framework for Xenobiotics–Microbiome interactions!

👉 Take the short survey (6–8 min): forms.gle/JNATejDrV2LR...

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