@pergamic
Transplant ID Doc and IP Director @Fred Hutchinson Cancer Center/ Faculty @UWMedicine. #InfectionPrevention #TxID #vaccines #prevention #protection #medtwitter Posts/comments are my own and not reflective of my institutions.
Antifungal susceptibility testing across fungi: why MICs vary, methods diverge, and what MIC can miss
Cornelia Lass-Flörl and colleagues
Open access in @cmijournal.bsky.social
www.clinicalmicrobiologyandinfection.org/article/S119... #IDSky #MedMycoSky
✋
The album - White light from the mouth of infinity
Brilliant
Six years ago WHO declared COVID-19 a pandemic. Despite tens of millions of deaths, the world has not sufficiently addressed the ongoing impacts of COVID-19, and we are more vulnerable to future pandemics due to anti-science officials leading government agencies around the world.
Great work by @uwidfellowship.bsky.social fellow extraordinaire @paulinavegamd.bsky.social
Fusariosis remains an important pathogen in hematologic malignancy patients in the azole prophylaxis era.
onlinelibrary.wiley.com/doi/10.1111/...
Two global health researchers who both spoke at @sufsseattle.bsky.social
At left, Chetan Seshadri, and at right, Darrick Carter. #tuberculosis #schistosomiasis #gobalhealth #research #NTD #IDsky
Bravo!
Maybe a highlight for any scientist or clinician - having an ice cream flavor made in honor of you!
Congrats to my colleague @fredhutch.org Dr Rachel Issaka
mollymoon.com/blog/dr-rach...
Emerging risk factors for IFI in HCT. Climate change, older/comorbid recipients, antifungal prophylaxis, changes in GVHD prophylaxis and treatment, longer survivorship, agricultural use of antifungals
Invasive Fungal Disease in Allogeneic Hematopoietic Cell Transplantation: New Risk Factors and New Therapeutic Options in a Changing World
@abbydouglas.bsky.social & Monica Slavin
doi.org/10.1111/tid.... #TxID #IDSky #MedMycoSky
A titan of vaccine development sees his field’s achievements slip away www.statnews.com/2026/03/02/s... via @statnews.com @helenbranswell.bsky.social
There is sadness in knowing that years from now pediatricians see more of these tragic situations
Unregulated stem cell therapy is scary stuff
We are still accepting applications for our #TID fellowship/advanced training year at UCLA for 2026-27 ☀️ 🌴 - please reach out w any questions about this opportunity! recruit.apo.ucla.edu/JPF10380 #MedEd #IDSky @txidfellows.bsky.social @ast-idcop.bsky.social @idsainfo.bsky.social @idjclub.bsky.social
That's right. Worse than Pointless
www.nytimes.com/2026/02/23/o...
A case of liver necrosis 2/2 isavuconazole in a patient with genetic mutation leading to low CYP3A5 activity.
😳 Detectable levels 3 months after medication stopped
🤔 Authors suggest ALT/AST testing and TDM in older pts who have longer Isavu courses
#IDSky
academic.oup.com/ofid/advance...
#PROSPECTOR Trial is out in NEJM Evidence 🔥
➡️ evidence.nejm.org/doi/full/10....
✅ 1st double-blind, placebo RCT in #drugallergy
✅ Pilot feasibility RCT
✅ 1-dose vs 5-day amoxicillin challenge in delayed/unknown #penicillinallergy
We’re going to answer… Is 1 dose ever enough? 👀 #PROSPECTOR2
The Northeast US is getting wetter with climate change, which may favor outbreaks of the fungal infection blastomycosis. Blasto seems to be emerging in upstate New York; prior reports have suggested that blasto is also on the rise in New England (immunosuppressive drugs may also be a factor)
White House stalls release of approved US science budgets: The administration has not yet released funding Congress allocated to multiple research agencies, so they cannot provide it to funded entities/people - including NIH and NASA. www.nature.com/articles/d41...
Dr. DeMeules is now a Resident at Univ Minnesota who led the study - developed during her time working in the Fredricks lab @fredhutch.org
More about their work?
research.fredhutch.org/fredricks/en...
🚨 New from DeMeules & collaborators at @fredhutch.org Fredricks' lab, describing 🦠 GI mono-domination in post HCT recipients & bacteremia.
*IP teams - Data suggests that many reported CoNS events from mucosal barrier/gut in these high risk pts. Important for CLABSI definitions
tinyurl.com/yn7zsxfx
Just noting that these details are concerning for H5N1 and its spread to other species.
But the image of the swab collection is just *chef's kiss
Elephant seals are massive animals who are territorial during breeding season....
Bird flu confirmed in California elephant seals for the first time, bringing the same virus to the U.S. that killed more than 17,000 elephant seals in South America.
www.latimes.com/science/stor...
Measles
Get used to seeing it
Mumps activity now in California and Maryland
Mumps (R0 10-12) is not quite as contagious as measles (R0 12-18), but it's pretty close. Serious complications include encephalitis, meningitis, orchitis (testicular inflammation), myocarditis, pancreatitis, and nephritis
#IDSky. The impact of the measles epidemic is enormous -misery, costs, and disruption. One tragic consequence, while rare, will be an increase in SSPE in a few years. I've seen one case and it was one of the saddest things I have ever seen-and that is saying a lot. www.nejm.org/doi/full/10....
This just in: the B/Yamagata lineage of influenza B is still extinct
This seems like a terrible idea
"The Chicago Department of Public Health (CDPH) is currently monitoring a cluster of invasive meningococcal disease (IMD) cases.
Since January 15, 2026, ten adult cases and two related fatalities have been confirmed."
www.vax-before-travel.com/2026/02/19/c...
Expect that this will become more and more common as insurance companies get more control through decisions made by HHS
It is frustrating as physician.
Devastating as a patient.
librarians are unbelievable assets that are so underutilized in science
