M-PACT leverages cell-free DNA methylomes to achieve robust classification of pediatric brain tumors - Nature Cancer Smith et al. present M-PACT, a deep neural network leveraging low-input cell-free DNA methylation profiles to achieve robust classification of pediatric brain tumors and enable cellular deconvolution ...

Excited to share our latest work—establishing a pipeline for DNA methylation–based CNS tumor diagnostics from minimally invasive CSF liquid biopsies—published today in Nature Cancer! Huge thanks to all collaborators. www.nature.com/articles/s43... #LiquidBiopsy #PediatricNeuroOncology #TeamScience

The EMBO Young Investigator Network consists of young investigators, installation grantees and global investigators. 🧪

Find more information on the individual programmes here:
www.embo.org/the-embo-communities/emb...
#LifeSciences #research #funding

SS18::SSX activates Polycomb target genes without BAF ❌
Instead, transcription relies on EP300 via the SS18 QPGY domain
www.biorxiv.org/content/10.6...
➡️ Coactivator targeting emerges as a new therapeutic strategy in synovial sarcoma 🎯
Team work from @banitolab.bsky.social and @uoe-igc.bsky.social

Why do so few cancer cells manage to form metastases - and what helps the rare ones succeed?

Delighted to share our first publication of 2026 🎉🎉, led by the outstanding @lbejarano.bsky.social 🤩, where we reveal some insights into this - focusing on brain metastasis 🧠🧪🔬

www.cell.com/cell-reports...

Overcoming immune evasion in solid tumours New findings from team KOODAC

Team #KOODAC ’s first @cellpress.bsky.social paper uncovers how MYC helps solid tumours evade immune detection—revealing a new model with major implications for immunotherapy.

Read the story behind the science
👇
Q&A: shorturl.at/7FXUw
Paper: shorturl.at/DYuWO

#CancerResearch #ImmunoOncology #MYC

Join us:

With @abigailsuwala.bsky.social we are looking for a postdoc to drive our spatial transcriptomics analysis efforts of brain tumours.

If you enjoy multidisciplinary biomedical research, big data and coding, you are in the right place.

karriere.klinikum.uni-heidelberg.de/index.php?ac...

This will be a very exciting meeting!
Looking forward to see you there
Please spread the word

Enhancer-promoter interactions Genome Biology is calling for submissions to our Collection on enhancer-promoter interactions. Enhancer–promoter interactions are central to the regulation ...

I'm guest-editing a collection on "Enhancer-promoter interactions" at Genome Biology. Please send us your exciting stories!

link.springer.com/collections/...

Register for the next EuSARC conference in Oslo, Norway, in June 2026

oslocancercluster.no/events/8th-e...

JCI - High 4E-BP-1 expression associates with chromosome 8 gain and CDK4/6 sensitivity in Ewing Sarcoma

Check out our new paper @jci.org

High 4E-BP-1 expression associates with chromosome 8 gain and CDK4/6 sensitivity in Ewing Sarcoma

www.jci.org/articles/vie...

We show that chr8 gains drive poor outcome in EwS via 4E-BP-1

@dkfz.bsky.social
@nct-heidelberg.bsky.social
@uniheidelberg.bsky.social

We are recuiting two new Associate Professors here in Oxford Biochemistry. Come join us! Reach out to me if you have any questions. Please repost! tinyurl.com/mr3m7bd3

The next #ScienceatDKFZ event will take place on Thursday, 23 October 2025, at 4 pm. In addition to the keynote lecture by @stefaniespeidel.bsky.social, there will be four 5-minute short talks by DKFZ junior scientists on recent highlight publications.

👉 dkfz.de/en/news/even...

Excited to try it out!

Please join the chorus of voices, including my own, in support of the talented, hardworking and dedicated scientists and staff at NIH. They serve their country by deploying their training and skills to improve the health and quality of life of all Americans 🙏 🇺🇸

Few days left to apply for a #postdoctoral position in my team investigating the pathomechanism of IDH1 mutations at the interface of #metabolism and #epigenomics!

Research Technician

Looking for a job as a #Research #Technician in #Cancer #Microbiome?
We offer a collaborative team, diversity of methods, opportunity for further training and a stimulating & fun work place at DKFZ @dkfz.bsky.social!
Apply now to our group (or share with your network):
jobs.dkfz.de/en/jobs/1671...

Are you interested in groundbreaking research in the field of personalized cancer therapies? If so, please join us at DKFZ for an exciting and inspiring afternoon and hear from key opinion leaders and rising stars about what is on the horizon.

Apply to DKFZ Marie Skłodowska Curie MasterClasses

Do you want to do your #postdoc in #cancerresearch with the most prestigious #fellowship in Europe? Apply to DKFZ Marie Skłodowska Curie MasterClasses by May 19. Projects in #cellandmolecularbiology #genomics #bioinformatics #immunology #medicaltechnology, #epidemiology.
Apply here: t1p.de/nx6tu