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MRC Laboratory of Molecular Biology

@mrclmb.ac.uk

The MRC Laboratory of Molecular Biology aims to understand biological processes at the molecular level to help tackle human health problems and disease.

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Latest posts by MRC Laboratory of Molecular Biology @mrclmb.ac.uk

From the scientist's view: a conversation with Sean Munro
From the scientist's view: a conversation with Sean Munro YouTube video by MRC Laboratory of Molecular Biology

For our annual alumni newsletter, Sean Munro reflected on his time at the LMB, including how opportunity and curiosity have shaped his groupโ€™s research into the Golgi apparatus and his tenure as Head of Division for @cellbiol-mrclmb.bsky.social
Watch the interview: youtu.be/xFGb7_RmO9c

13.03.2026 14:57 ๐Ÿ‘ 7 ๐Ÿ” 4 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Microscopy image taken by a light sheet microscope showing an optically cleared lung in blue.

Microscopy image taken by a light sheet microscope showing an optically cleared lung in blue.

Interested in instrument development & optical microscopy?
Join @immunoah.bsky.social & @jamesdmanton.bsky.social developing high-throughput light sheet microscopy to image entire tissues & progressing tissue clearing methods
www.nature.com/naturecareer...
Closes 07 APR
#PostdocJobs #neuroimmunology

13.03.2026 10:18 ๐Ÿ‘ 7 ๐Ÿ” 2 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 1
Preview
Why did some mammals evolve to prefer daylight activity? A study inย the UK has foundย changesย in cellsย thatย explainย whyย mammals,ย including human ancestors,ย changedย fromย nocturnal toย diurnal,ย providing clues on one of the most relevant events in mammalianโ€ฆ

Researchers @mrclmb.bsky.social found changes in cells that explain why #mammals, including human ancestors, changed from #nocturnal to #diurnal, providing clues on one of the most relevant events in mammalian #evolution.
๐Ÿ”— www.eara.eu/post/why-did...
#AnimalResearch #CircadianClock #circadian

12.03.2026 13:00 ๐Ÿ‘ 2 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Preview
BBC Radio 4 - In Our Time, Archaea How a discovery in the 1970s changed the theory of the origin of complex life on earth.

On todayโ€™s episode of BBC Radio 4โ€™s In Our Time, @buzzbaum.bsky.social, Group Leader in @cellbiol-mrclmb.bsky.social, joined for a discussion on all things archaea.
Check it out here (requires BBC login): www.bbc.co.uk/programmes/m...
#LMBintheNews

12.03.2026 12:46 ๐Ÿ‘ 19 ๐Ÿ” 6 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 1
Portrait of Ruth Lehmann with text about her talk on reconstructing biomolecular condensates for translation on March 27th.

Portrait of Ruth Lehmann with text about her talk on reconstructing biomolecular condensates for translation on March 27th.

Weโ€™re delighted to welcome Ruth Lehmann (@remlehmann.bsky.social), Director of @whiteheadinstitute.bsky.social as our next #LMBSeminar speaker!
Join us at 11am on Friday 27th March to hear all about โ€œReconstructing biomolecular condensates for translationโ€
More info: mrclmb.ac.uk/news-events/...

11.03.2026 10:14 ๐Ÿ‘ 6 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Madeline Lancaster

Madeline Lancaster

@lancasterlab.bsky.social, Joint Head of the LMBโ€™s Cell Biology Division (@cellbiol-mrclmb.bsky.social), was recognised in the 2026 Suffrage Science Awards for her work on brain organoids ๐Ÿง 

Congratulations to Madeline and the other 2026 awardees!

Read more: mrclmb.ac.uk/news-events/...

#LMBNews

10.03.2026 09:16 ๐Ÿ‘ 15 ๐Ÿ” 4 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
Advert for the Cambridge Biomedical Campus Careers Fair

Advert for the Cambridge Biomedical Campus Careers Fair

Interested in working at the LMB?
Come and chat to us at the @cambridgebiocampus.bsky.social Careers Fair this Wednesday 11th March at Cambridge Academy for Science and Technology!
More details here: cambridge-biomedical.com/event/cbc-ca...

09.03.2026 14:11 ๐Ÿ‘ 2 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Anne Bertolotti

Anne Bertolotti

Weโ€™re looking for a creative & enthusiastic postdoc with expertise in cryo-EM or protein biochemistry to join @annebertolotti.bsky.social (LMB Neurobiology Division) and help solve structures of key stress signalling enzymes and develop new inhibitors.
www.nature.com/naturecareer...
Apply by 22 MAR

09.03.2026 09:33 ๐Ÿ‘ 7 ๐Ÿ” 8 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
From the scientist's view: a conversation with Joseph Yeeles
From the scientist's view: a conversation with Joseph Yeeles YouTube video by MRC Laboratory of Molecular Biology

Joseph Yeeles (@yeeles-lab.bsky.social) leads a group in the LMBโ€™s PNAC Division studying DNA replication.
For our annual alumni newsletter, Joseph shared what inspired his path in science, how his research has evolved and the value of mentoring future scientists.
Watch here: youtu.be/3ok-Fqr3HB4

06.03.2026 15:18 ๐Ÿ‘ 9 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Industrial facility interior with complex piping and ducts, advertising a Maintenance Engineer job opening at MRC Laboratory of Molecular Biology.

Industrial facility interior with complex piping and ducts, advertising a Maintenance Engineer job opening at MRC Laboratory of Molecular Biology.

Weโ€™re looking for a Maintenance Engineer to join our skilled Estates & Facilities team!
Youโ€™ll be responsible for electrical or mechanical works to keep the LMB buildings running in optimal condition.
Read more here: www.jobs.ac.uk/job/DQQ890/m...
Apply by 25 MAR
#CambridgeJobs

06.03.2026 10:41 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Congratulations to #LMBAlumni @leokiss.bsky.social who is starting his own research group at the University of Duisburg-Essen!
We canโ€™t wait to hear all your ubiquitin discoveries - Best of luck Leo!

05.03.2026 14:38 ๐Ÿ‘ 3 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Logo for the Graduate Student Symposium 2026, a partnership between LMB and EPFL

Logo for the Graduate Student Symposium 2026, a partnership between LMB and EPFL

For the 20th anniversary of the LMBโ€™s graduate student symposium our students are teaming up with EPFL to plan @lmbphdsymposium.bsky.social!

๐Ÿ“… When? 2-3 July 2026

Registration will open shortly and abstracts on your research are welcome!
Find out more: www3.mrc-lmb.cam.ac.uk/sites/gsasym...

04.03.2026 12:05 ๐Ÿ‘ 7 ๐Ÿ” 2 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Kaz Collins, stood in front of cupboards holding glass bottles

Kaz Collins, stood in front of cupboards holding glass bottles

Last year, the LMB was delighted to welcome Kaz Collins as the new Manager of the Media Prep and Glasswash facility.
Read more about the work they do to support LMB researchers here: mrclmb.ac.uk/news-events/...
#LMBNews

03.03.2026 12:04 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Aviv Regev smiling, stood in front of a blurred background

Aviv Regev smiling, stood in front of a blurred background

The LMB is delighted to welcome Aviv Regev to deliver the 2026 Francis Crick Lecture on Monday 9th March at 11am (GMT).

Read all about her talk, โ€˜From Cell Atlases to Medicines, with AIโ€™ here: mrclmb.ac.uk/news-events/...

#LMBNews #LMBSeminar

02.03.2026 10:00 ๐Ÿ‘ 10 ๐Ÿ” 2 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Person on ladder adjusting clock hands against a sky transitioning from day to night.

Person on ladder adjusting clock hands against a sky transitioning from day to night.

New #LMBResearch led by @drbatmo.bsky.social in John Oโ€™Neillโ€™s group (@cellbiol-mrclmb.bsky.social) has identified the molecular switch decides day or night.

Click here to read how the mTOR pathway controls when mammals are active and the role itโ€™s played in evolution: mrclmb.ac.uk/news-events/...

27.02.2026 09:59 ๐Ÿ‘ 8 ๐Ÿ” 5 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 2
Post image Post image Post image Post image

Anyone you recognise? Here are some of the brilliant performers we had at our Open Mic Night back in November, which returns in two weeks on 10th March!

Book your spot in advance to guarantee your turn on the mic, then get practicing...

cambridge-biomedical.com/event/open-m...

24.02.2026 16:12 ๐Ÿ‘ 1 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Kelly Nguyen announced as Laureate in Life Sciences at the 2026 Blavatnik Awards in the UK.

Kelly Nguyen announced as Laureate in Life Sciences at the 2026 Blavatnik Awards in the UK.

Congratulations to @kellythd-nguyen.bsky.social, Group Leader in the LMBโ€™s Structural Studies Division, who has been named the Life Sciences Laureate at the 2026 Blavatnik Awards in the UK ๐ŸŽ‰

Read the full news story here: mrclmb.ac.uk/news-events/...

#LMBNews #Blavatnik2026

25.02.2026 09:03 ๐Ÿ‘ 71 ๐Ÿ” 11 ๐Ÿ’ฌ 2 ๐Ÿ“Œ 3
Job opening for Research Group Leader in Structural Studies at MRC Laboratory of Molecular Biology, focusing on macromolecular structures.

Job opening for Research Group Leader in Structural Studies at MRC Laboratory of Molecular Biology, focusing on macromolecular structures.

Are you a structural biologist pushing the boundaries of molecular science with an ambitious research programme?
Join our Structural Studies Division as a tenure-track Group Leader, with core funding, world-leading facilities & enthusiastic colleagues.
Apply by 16 MAR
www.nature.com/naturecareer...

24.02.2026 09:45 ๐Ÿ‘ 36 ๐Ÿ” 48 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 2
Promotional banner for the 2026 Francis Crick Lecture, to be given by Aviv Regev at the LMB on Monday 9th March.

Promotional banner for the 2026 Francis Crick Lecture, to be given by Aviv Regev at the LMB on Monday 9th March.

Donโ€™t miss the 2026 Francis Crick Lecture by Aviv Regev from Genentech!
Aviv will be joining us on Monday 9th March to discuss โ€˜From Cell Atlases to Medicines, with AIโ€™
More details on our website: www2-dev/nairobi/news...
#LMBSeminar

23.02.2026 14:58 ๐Ÿ‘ 4 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Work experience ad. Year 12 rotation July 27th-31st. Apply by 1st March.

Work experience ad. Year 12 rotation July 27th-31st. Apply by 1st March.

It's the last week to apply for the LMBโ€™s rotation work experience placements!

๐Ÿ—“๏ธ 27th to 31st July

Eligibility and selection criteria apply.

Apply by 01/03

Read more: mrclmb.ac.uk/careers-and-...

#STEM #WorkExperience #BiologyCareers

23.02.2026 09:27 ๐Ÿ‘ 2 ๐Ÿ” 4 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Head of Finance ad.
Closing 12th March.

Head of Finance ad. Closing 12th March.

The LMB is looking for an experienced finance leader to shape our financial strategy & guide key decisions. Youโ€™ll drive strategic planning, lead financial reporting improvements & work closely with senior partners across MRC and UKRI.

Apply by 12 MAR

www.jobs.ac.uk/job/DQM376/h...

19.02.2026 09:56 ๐Ÿ‘ 0 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Red envelopes with gold characters arranged on a wooden table for Lunar New Year celebrations.

Red envelopes with gold characters arranged on a wooden table for Lunar New Year celebrations.

Wishing everyone celebrating a very happy Lunar New Year!
#LunarNewYear #YearOfTheHorse ๐Ÿงง๐Ÿด

17.02.2026 16:27 ๐Ÿ‘ 8 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Preview
Molecular Techniques Training Seminars 2025-26 - YouTube The recordings are from the LMB's recent series of training seminars 'Biophysical Techniques Course: Solving Probes with Molecular Techniques.'Featuring expe...

Interested in all the molecular techniques available at the LMB to help researchers?
Check out this lecture series on our Youtube channel: www.youtube.com/playlist?lis... ๐Ÿงช

17.02.2026 15:33 ๐Ÿ‘ 5 ๐Ÿ” 2 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Preview
A small polymerase ribozyme that can synthesize itself and its complementary strand The emergence of a chemical system capable of self-replication and evolution is a critical event in the origin of life. RNA polymerase ribozymes can replicate RNA, but their large size and structural ...

How could a simple self-replicating system emerge at the origins of life? RNA polymerase ribozymes can replicate RNA, but existing ones are so large that their self-replication seems impossible. Could they be smaller?

Excited to share our latest work in @science.org on a new small polymerase.
1/n

13.02.2026 11:42 ๐Ÿ‘ 498 ๐Ÿ” 210 ๐Ÿ’ฌ 10 ๐Ÿ“Œ 28

Researchers have discovered a little RNA molecule - small enough to potentially form spontaneously, yet sophisticated enough to begin to copy itself - that could explain how life on Earth began over four billion years ago, Science Director @rogerhighfield.bsky.social reports: https://bit.ly/3ZvPS6s

12.02.2026 19:30 ๐Ÿ‘ 14 ๐Ÿ” 6 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 5
Video thumbnail

How did life arise from simple chemical building blocks?

New #LMBResearch led by @edogia.bsky.social in @philholliger.bsky.social group has identified a small self-replicating ribozyme that could be the answer.

Read more: mrclmb.ac.uk/news-events/...

13.02.2026 10:20 ๐Ÿ‘ 52 ๐Ÿ” 31 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 2
Kelly Nguyen announced as finalist of 2026 Blavatnik Awards in the UK. Kellyโ€™s face and name on a black background with blue patterns.

Kelly Nguyen announced as finalist of 2026 Blavatnik Awards in the UK. Kellyโ€™s face and name on a black background with blue patterns.

@kellythd-nguyen.bsky.social, Group Leader in the Structural Studies Division, has been announced as a Finalist in the 2026 Blavatnik Awards for her work on telomerase.

Congratulations to Kelly and to all the other Finalists!

Read more here: blavatnikawards.org/news/items/y...

#LMBintheNews

10.02.2026 09:34 ๐Ÿ‘ 37 ๐Ÿ” 4 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 4
Preview
How RNA reveals clues to lifeโ€™s origins on Earth The discovery of catalytic RNA transformed our understanding of life's beginnings. Clare Sansom explores how the RNA world hypothesis bridges the gap between non-living chemistry and the first cells

How did life on Earth begin?

LMB Group Leader John Sutherland posits that the building blocks for life could have emerged simultaneously from early-Earth chemistry, kickstarted by hydrogen cyanide.

Read more about this field of research here: www.chemistryworld.com/features/how...

#LMBintheNews

09.02.2026 10:39 ๐Ÿ‘ 9 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 1
Smiling headshot of Matti Pronker

Smiling headshot of Matti Pronker

Congratulations to former LMB postdoc @mfpronker.bsky.social, who is launching his own independent research group at Sanquin Research where he'll use protein engineering and structural biology techniques to study important blood protein complexes.
Best of luck to you Matti!
#LMBAlumni

05.02.2026 13:04 ๐Ÿ‘ 12 ๐Ÿ” 3 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Preview
Hidden struggles: Cambridge scientists share the truth behind their success In a career defined by constant questioning, self-doubt can become an occupational hazard. Now, for the first time, a group of Cambridge scientists reveal the personal struggles theyโ€™ve faced โ€“ and co...

Self-Doubt, the new book from @labliston.bsky.social, explores the uncertainty researchers face in their careers.
Several scientists share their stories, including Tombi Makuyana, a postdoc in the LMBโ€™s PNAC Division.
Read more about the book here: www.cam.ac.uk/stories/camb...
#LMBNews

03.02.2026 11:36 ๐Ÿ‘ 23 ๐Ÿ” 6 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 1