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Andy Fraser

@andyfraser

Finished just outside the top 3 Most Responsible Person in our 4 person household for a record 13 years.

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Latest posts by Andy Fraser @andyfraser

That’s fabulous cover art!

08.03.2026 04:04 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Figure 1. Cryo-EM of abundant protein complexes in native membranes.

Figure 1. Cryo-EM of abundant protein complexes in native membranes.

Figure 2. Cryo-EM of membrane proteins in vesicles.

Figure 2. Cryo-EM of membrane proteins in vesicles.

Figure 3. 3D reconstruction of V-ATPase in native synaptic vesicle membranes.

Figure 3. 3D reconstruction of V-ATPase in native synaptic vesicle membranes.

Figure 4. Generation of membrane vesicles for structure determination of proteins in their native lipid bilayer.

Figure 4. Generation of membrane vesicles for structure determination of proteins in their native lipid bilayer.

I've written a review on what I think is an extremely exciting direction in cryo-EM:

Cryo-EM of endogenous membrane proteins in their native lipid bilayer

Open access in Quarterly Reviews of Biophysics:
doi.org/10.1017/S003...

06.03.2026 12:40 πŸ‘ 150 πŸ” 56 πŸ’¬ 3 πŸ“Œ 1

Translation - the Kurds told him to F off.

07.03.2026 22:31 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

I miss the time when the murder of 160 schoolgirls would be cause for horror and condemnation and not obscene celebrating. Ah well. You do you, America.

07.03.2026 22:28 πŸ‘ 5 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

As this war unfolds, it’s beginning to look like it’s a parallel effort where Israel just wants to destroy Iran in a Gaza level war crime and America is dragged along through its bloated incontinent president and his nazi minister of war to try to plunder as much as they can. No other plan.

07.03.2026 22:25 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Green with envy. If I tried that it would be very funny for everyone except me.

07.03.2026 20:30 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Iran was already dangerously close to running out of drinking water before we attacked them.

Really gives the lie to β€œwe’re helping Iranians free themselves,” doesn’t it?

07.03.2026 20:25 πŸ‘ 106 πŸ” 44 πŸ’¬ 3 πŸ“Œ 2

Oh the good news just keeps rolling in doesn’t it? Thankfully Trump, hegseth, and Rubio have modelled this precisely and spent months on crafting a perfect plan to curtail the conflict and stop it spiralling out of control.

07.03.2026 20:26 πŸ‘ 0 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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These are Olena Udovichenko and her son Hordii.

A Russian missile killed them today.

Olena was a teacher in a Kharkiv school, Hordii was a second-grader there.

Last night, Russia killed 11 people in Kharkiv, including Olena and Hordii.
RIP.

07.03.2026 20:00 πŸ‘ 691 πŸ” 325 πŸ’¬ 44 πŸ“Œ 17
Chad kroeggggggrrrrr

Chad kroeggggggrrrrr

The singer from soundgarden

The singer from soundgarden

Identical twins

07.03.2026 20:12 πŸ‘ 1 πŸ” 0 πŸ’¬ 2 πŸ“Œ 0

Winter shrinkage. Every year.

07.03.2026 19:10 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Gavin Newsom, Kristi Noem Nod Silently To Each Other In Plastic Surgeon’s Office

Gavin Newsom, Kristi Noem Nod Silently To Each Other In Plastic Surgeon’s Office

Gavin Newsom, Kristi Noem Nod Silently To Each Other In Plastic Surgeon’s Office

07.03.2026 16:11 πŸ‘ 6461 πŸ” 786 πŸ’¬ 69 πŸ“Œ 44

I have only just realised that the singers of Soundgarden and Nickleback are two different people. I’m not sure I even believe it.

07.03.2026 18:09 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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So according to the WSJ a US Senator conspired with another country to manipulate the US into starting a war, am I getting this right

07.03.2026 16:25 πŸ‘ 10727 πŸ” 4233 πŸ’¬ 500 πŸ“Œ 423

What would be worse: that America and Israel’s illegal war succeeds or that it fails? Failure would be chaotic and awful - but success would empower these madmen even more to ever more insane and hideous war crimes and assaults on other countries.

07.03.2026 17:34 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

My brother, we had to explain a 1/3 pound burger was bigger than a quarter pound burger and still failed

07.03.2026 16:41 πŸ‘ 5694 πŸ” 952 πŸ’¬ 65 πŸ“Œ 20
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Interesting hand signal from Pete Hegseth this morning

07.03.2026 15:17 πŸ‘ 826 πŸ” 322 πŸ’¬ 153 πŸ“Œ 109
Preview
With speed cameras out, Toronto faces decade-long safety rebuild with a price tag of $52M Speed cameras across Ontario were removed in November with the passing of provincial legislation that banned them after Premier Doug Ford called them a β€œcash grab” for municipalities.

The City of Toronto says the traffic-calming measures needed to replace speed cameras removed by Ford will cost $52 million and take 13 years to install. The passing of Bill 60 (which limits new bike lanes) combined with speed camera removal, is concerning cyclists. For @nationalobserver.com #OnPoli

04.03.2026 16:38 πŸ‘ 17 πŸ” 6 πŸ’¬ 2 πŸ“Œ 0
Job Details

Pls re-post: My department @oxfordbiochemistry.bsky.social are recruiting for several new faculty positions (links below). Broad search in molecular biology/biochemistry, across prokaryotes and eukaryotes. Interested in understanding life at the molecular level, this job might be for you!
1/n

05.03.2026 21:35 πŸ‘ 85 πŸ” 123 πŸ’¬ 2 πŸ“Œ 3

There’s only so long a lying administration can hide the reality - they cooked the figures several times in a row and finally they can’t keep up the fantasy. The scary thing is how the media and financial markets believed/pretended to believe this gang of crooks and idiots for so long.

07.03.2026 14:17 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
The Iran War Is Unfathomably Depraved Our media’s sanitized coverage obscures the human toll. Are we able to confront the full sickening evil of what the U.S. is doing?

This is a hard but necessary read.

"Our media’s sanitized coverage obscures the human toll. Are we able to confront the full sickening evil of what the U.S. is doing?"

www.currentaffairs.org/news/the-ira...

07.03.2026 12:56 πŸ‘ 42 πŸ” 26 πŸ’¬ 3 πŸ“Œ 0

SΓ‘nchez: β€œYou may have heard that Spain is alone. They’re the same people who said that when we recognized the State of Palestine, and then others followed.

β€œWe are not alone β€” we are the first. Those who will end up alone are the ones defending the indefensible.”

07.03.2026 11:55 πŸ‘ 2603 πŸ” 711 πŸ’¬ 25 πŸ“Œ 56
Preview
'All those suffering from US and Israeli aggression are our strategic partners,' Russia's Lavrov says Russia's Foreign Minister Sergey Lavrov said Thursday that "all those suffering from U.S. and Israeli aggression are our strategic partners."

Watch this. This is the world Trump is leaving us with. He has pushed the snowball down the hill to a new world war
apnews.com/video/all-th...

07.03.2026 13:04 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

The killing of Iranian children during an illegal war is an impeachable offense (not to mention a grave crime) and Congress should really act like it.

15 Republicans in the Senate could end this nightmare before it somehow gets even worse.

07.03.2026 02:13 πŸ‘ 12872 πŸ” 3598 πŸ’¬ 470 πŸ“Œ 165
Preview
FDA’s controversial vaccine chief will exit agency next month | CNN The US Food and Drug Administration’s head of vaccines and biologic medicines will leave the agency at the end of April, a spokesperson confirmed to CNN on Friday.

Vinay Prasad has been an a noxious influence on public health and drug regulation. Good riddance. UCSF should not take him back. He should wander in the wilderness forever. www.cnn.com/2026/03/06/h...

06.03.2026 23:39 πŸ‘ 920 πŸ” 228 πŸ’¬ 32 πŸ“Œ 19

Hegseth needs to stand trial after this as a war criminal. Between this attack and the girls' school, there's no ambiguity. He is responsible for mass murder and must be held accountable.

07.03.2026 01:32 πŸ‘ 5967 πŸ” 1742 πŸ’¬ 111 πŸ“Œ 56

Trump said the same on truth social, paraphrase β€œwe had a meeting today to decide to quadruple production and also um they had already started that two months ago”

07.03.2026 01:51 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Oh.

β€œWe have agreed” β€” how nice of them! Surely they’re doing this work pro bono right?

07.03.2026 01:26 πŸ‘ 9562 πŸ” 3790 πŸ’¬ 589 πŸ“Œ 309

Ladies and gentlemen, allow me to introduce you to Vinay Prasad, M.D.

07.03.2026 00:34 πŸ‘ 30 πŸ” 10 πŸ’¬ 3 πŸ“Œ 0

Christ looking at current events I’m wondering if there has been some memory extinction event and nobody can remember anything that happened before 2025

07.03.2026 00:33 πŸ‘ 5 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0