Sign up by 6 March for the EMBO Lab Leadership #training "How to write a scientific paper" delivered by EMBO Press editors at EMBO | EMBL Symposium "#AI and #biology." 🧪 https://www.embl.org/about/info/course-and-conference-office/events/ees26-02/#vf-tabs__section-embo_training #EESAIBio #EMBOevents
Structure-guided design of a PfCyRPA-based #vaccine against blood-stage #malaria
➡️ doi.org/10.1038/s44321-026-00376-x
By N. Alam, @parasitematt.bsky.social and colleagues @ox.ac.uk @kavlioxford.bsky.social
Read this @emboreports.org paper here=> link.springer.com/article/10.1...
KCNA2 variants cause dilated #cardiomyopathy, #obesity and #SleepApnea through RAC-ERK pathway
By P. Chimata, P. Dhandapany & colleagues at Institute for Stem Cell Science and Regenerative Medicine
👉 doi.org/10.1038/s44321-026-00391-y
#CITED2 is a druggable #EpigeneticSwitch coupling neuronal maturation to regenerative decline
By F. Müller, S. Di Giovanni & colleagues @imperialcollegeldn.bsky.social
🗞️ doi.org/10.1038/s44321-026-00385-w
Online today! ➡️ doi.org/10.1038/s44321-026-00387-8
Sulfated #glycosaminoglycans inhibit #LCMV entry and modulate antiviral immunity and pathology
By M. Gorzkiewicz, P. Lang & colleagues @hhu.de
Epigenetic dysregulation of IRF9 drives excessive #interferon signaling in #COPD
By M. Llamazares-Prada, R. Jurkowska & colleagues @biomedx.bsky.social & Cardiff University
🗞️ doi.org/10.1038/s44321-026-00386-9
#Encephalopathy linked #UFM1 variants impede neuronal protein translation, development, and function
By C. Perdigão, N. Brose, M. Tirard & colleagues @mpi-nat.bsky.social
👉 doi.org/10.1038/s443...
KRAS-dependent glycolytic reprogramming of endothelial cells in #SporadicArteriovenousMalformations
By R. Wu, J. Fish and colleagues @utoronto.ca @uhn.ca
🗞️ doi.org/10.1038/s443...
Read also related N&V by M. Rudnicki and T. Haas 👉 doi.org/10.1038/s443...
New issue online! ➡️ link.springer.com/journal/4432...
This month's cover highlights the article by J. Haas, B. Meder and colleagues at Heidelberg University and German Center for Cardiovascular Research
🗞️ doi.org/10.1038/s443...
I was honored to be profiled by Churchill College regarding our recent @embomolmed.org paper out of the Jackson lab (www.stevejacksonlab.org) on MAEA, DNA repair/replication, and a new diagnosis, DIADEM.
(I tried to aim my answers at a general audience.)
www.chu.cam.ac.uk/news-and-eve...
A bactericidal #tuberculosis drug regimen driven by inhibition of the terminal oxidases by #pretomanid -> doi.org/10.1038/s44321-026-00378-9
By N. Ab Rahman, K. Pethe & colleagues at Nanyang Technological University, National Centre for Infectious Diseases & @ineosoxford.bsky.social
Dextrorotatory kynurenine suppresses #AcuteRejection through inhibiting M1 macrophage-mediated #inflammation
By Y. Zhao, Y. Guo, C. Yang, D. Zhu & colleagues at Fudan University & Chinese Academy of Sciences
➡️ doi.org/10.1038/s44321-026-00377-w
[PUBLICATION] The @goffinlab.bsky.social lab shows a promising therapeutic strategy to mitigate prostate cancer progression towards CRPC — now out in EMBO Molecular Medicine @embomolmed.org
👏🏼 Co-first authors: Manon Baurès & Anne-Sophie Vieira Aleixo
🔗 link.springer.com/article/10.1...
Grateful to @cambiochem.bsky.social for spotlighting my PhD work, recently published in @embomolmed.org.
We're really proud of this international collaboration between a wide range of researchers and clinicians. Thanks to everyone involved!
www.bioc.cam.ac.uk/news/embo-mo...
Targeting pre-existing club-like cells in #ProstateCancer potentiates #AndrogenDeprivationTherapy by M. Baurès, F. Rambow, @goffinlab.bsky.social & colleagues @inem-necker.bsky.social and Institute for AI in Medicine (IKIM)
➡️ doi.org/10.1038/s443...
Characterization and therapy of #fertilization failure in murine and human models with HNRNPR mutations ➡️ doi.org/10.1038/s443...
by S. Gan, C. Zhang, W. Yang, Y. Li, H. Huang and colleagues at Zhejiang University
Our @embojournal.org editor Daniel Klimmeck is looking forward to the #MitoCellFate conference in May. Submit poster abstracts and registration until February 9th => bit.ly/43AaInH @fusionconf.bsky.social
Explore emerging research with field leaders @keystonesymposia.bsky.social #CancerImmunotherapy : Mechanisms, Clinical Advances & Combinations, this March in Québec! hubs.la/Q03TCrxR0
#KSCancerImmune26
TKI-mediated inhibition of NLRP1 #inflammasome restores #erythropoiesis in Diamond-Blackfan anemia syndrome 👉 doi.org/10.1038/s443...
By J. Lozano-Gil, A. Martínez-López, S. Tyrkalska, V. Mulero & colleagues @ciberisciii.bsky.social & @um.es
#ExtracellularVesicle -based targeted #ProteinDegradation platform for multiple extracellular proteins
By B. Tong, L. Tan, Z. Liao, C. Yang & colleagues at Huazhong University of Science and Technology
➡️ doi.org/10.1038/s443...
Sarcomeric remodelling in human #HeartFailure unraveled by single molecule #LongReadSequencing
By J. Haas, B. Meder & colleagues @uniheidelberg.bsky.social
Online today -> A viral glycoprotein targets IgG+ memory #Bcells to mediate humoral #ImmuneEvasion
by P. Cramer, M. Rizzi, H. Hengel and colleagues @uni-freiburg.de @univie.ac.at
🗞️ doi.org/10.1038/s443...
Our new issue is online! link.springer.com/journal/44321
The cover illustrates the study by B. Stringer, J. Giacomotto & colleagues that introduces a tool for assessing SMN1 pathogenicity in #SpinalMuscularAtrophy using the zebrafish model ➡️ doi.org/10.1038/s443...
Molecular profile of human ischemic cardiomyopathy in #diabetes reveals reduced mitochondrial complex I and elevated very long chain acylcarnitines @embomolmed.org
link.springer.com/article/10.1...
Great to see this team effort out, in which we find a new player in genome stability and a neurodevelopmental disease caused by its loss. Fantastic collaboration with @drjhujh.bsky.social and @profstewartlab.bsky.social alongside @sorenhough.bsky.social and friends in @spjacksongroup.bsky.social.
Mechanisms of resistance to #VHL loss-induced genetic and pharmacological vulnerabilities ➡️ doi.org/10.1038/s443...
By J. Ge, D. Muñoz-Espín, @svanharanta.bsky.social & colleagues @cam.ac.uk @helsinki.fi
Loss of CTLH component MAEA impairs #DNArepair and replication and leads to #DevelopmentalDelay
By S. Hough, S. Jackson & colleagues @cam.ac.uk @cruk-ci.bsky.social
🗞️ doi.org/10.1038/s443...
Online today! Mutant #CHCHD10 disrupts cytochrome c oxidation and activates mitochondrial retrograde signaling
by M. Campos-Ribeiro, T. Wai & colleagues @pasteur.fr
👉 doi.org/10.1038/s443...
New review by M. Pepin, X. Gong, A. Schulze and J. Backs @uniheidelberg.bsky.social ➡️Metabo-epigenetic circuits of #HeartFailure: chromatin-modifying enzymes as determinants of metabolic plasticity🫀
🗞️ doi.org/10.1038/s443...
