Neus Falgàs

Study links locus coeruleus status to deep sleep quality in aging and Alzheimer's disease This research describes new mechanisms linking the locus coeruleus to deep sleep and reveals differences according to sex and cerebral vascular status.

Using polysomnography + neuroimaging/biomarkers (58 participants), the team found that better-preserved locus coeruleus status was associated with higher slow-wave activity. 👇 www.barcelonabeta.org/en/news/news...

Relationship between locus coeruleus and slow‐wave sleep in aging and Alzheimer's disease INTRODUCTION Sleep disruption, particularly loss of slow-wave sleep (SWS), is common in Alzheimer's disease (AD), but its neurobiological underpinnings remain unclear. We investigated whether locus ...

alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

Our new paper shows that higher locus coeruleus integrity is linked to stronger slow-wave sleep across aging and Alzheimer’s—especially in women 🧠💤🙋‍♀️and points to a potential link with vascular/glymphatic health @hospitalclinic.bsky.social @idibaps.bsky.social @barcelonabeta.bsky.social

Genetically determined Alzheimer's disease research advances: The Down Syndrome & Autosomal Dominant Alzheimer's Disease 2024 Conference INTRODUCTION The Down syndrome-associated Alzheimer's disease (DSAD) autosomal dominant Alzheimer's disease (ADAD) 2024 Conference in Barcelona, convened under an Alzheimer's Association Internation.....

🚨Thrilled to share our paper of the first DSAD-ADAD conference, highlighting key discoveries in autosomal dominant Alzheimer’s disease (ADAD) and Down syndrome @hospitalclinic.bsky.social @hospitalsantpau.bsky.social @istaart.bsky.social 🧠👇 alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

📆 Mark your calendars for #AAIC25!

Do not miss this multidisciplinary and exciting perspective session on clinical trials for #AtypicalAD on July 29!

@rikossenkoppele.bsky.social @neusfalgas.bsky.social @corriveaunick.bsky.social @neguine.bsky.social @istaart.bsky.social

📢 Excited to announce the lineup for the @istaart.bsky.social #AtypicalPIA FRS at #AAIC25 on July 29! Mark your calendar to join us in person or online with @neusfalgas.bsky.social @leatgrinberg.bsky.social @rikossenkoppele.bsky.social @baaylab.bsky.social Drs. Deepti Putcha, Keir Yong, Colin Groot!

Interested in how sleep and brainstem dysfunction interact in Alzheimer’s? 😴🧠 Don’t miss this Conference! In-person & online. Register now! 👇🏻👇🏻👇🏻 @istaart.bsky.social @SleepPIA @NSS_PIA @heidijacobslab.bsky.social

Thrilled to host the #AAICNeuro Barcelona Hub at @hospitalclinic.bsky.social! A fantastic day showcasing early-career researchers in Alzheimer's disease 🧠 Huge thanks to all speakers, attendees, and especially @rikossenkoppele.bsky.social for his wonderful talk. Grateful to @istaart.bsky.social ✨

The Cortical Asymmetry Index for subtyping dementia patients - European Radiology Objectives Frontotemporal dementia (FTD) usually shows more asymmetric atrophy patterns than Alzheimer’s disease (AD). We aim to quantify this asymmetry to differentiate FTD, AD, and FTD subtypes. Met...

📢 Happy to share the last paper of my PhD!

link.springer.com/article/10.1...

We introduce CAI a cortical asymmetry index:

- Differentiates HC, AD & FTD (incl. phenotypes)

- Identifies 2 FTD clusters (differences NfL) & 2 AD clusters (differences GFAP)

- FTD ⬆️CAI over time

Welcome! You are invited to join a webinar: Neuromodulatory Subcortical Systems PIA: Tiny Dots - Noradrenergic Axon Loss Drives Hyposmia in AD. After registering, you will receive a confirmation email... Early-onset degeneration of hyperactive locus coeruleus axons in the olfactory bulb drives olfactory dysfunction in Alzheimer’s disease via phosphatidylserine-MFG-E8 signaling and microglial clearance...

I am very much looking forward to this week with 2 meetings of the Neuromodulatory Subcortical System PIA:
📌 Tiny dots 21.01.25 12.30am CT (USA) - Noradrenergic Axon Loss Drives Hyposmia in AD
alz-org.zoom.us/webinar/regi...

📌 Year in Review 24.01.25 10am CT (USA) alz-org.zoom.us/webinar/regi...

"A study of federally funded research projects in the United States estimated that principal investigators spend on average about 45% of their time on administrative activities related to applying for and managing projects rather than conducting active research"

www.pnas.org/doi/10.1073/...

Tiny Dots: Noradrenergic Axon Loss Drives Hyposmia in AD ISTAART Neuromodulatory Subcortical Systems PIA: Tiny Dots - Noradrenergic Axon Loss Drives Hyposmia in AD - 21st January, 5.30pm GMT

ISTAART Neuromodulatory Subcortical Systems PIA: Tiny Dots - Noradrenergic Axon Loss Drives Hyposmia in AD - 21st January, 5.30pm GMT

www.dementiaresearcher.nihr.ac.uk/event/tiny-d...

🎉 Registration is still OPEN for #AAICNeuro Neuroscience Next Barcelona Hub! #ISTAART @alzassociation.bsky.social
🗓️ Feb 25-26, 2025
📍 Hospital Clínic - University of Barcelona @hospitalclinic.bsky.social
💡 Register for FREE at: alz.org/neurosciencene…