Kudos to the authors!
23.02.2026 03:07
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Kudos to the authors!
The present:
The future:
Clinical syndromes post-acute PE:
PERT activation:
Pulmonary embolism response teams:
Long time overdue. Hopefully it will make people pay more attention to CO even though we will continue to be focused on BP...
Initial assessment and management by AHA/ACC acute PE clinical categories:
Thanks, just found 2 studies
I admit that I did not remember this. Is a MAP < 80 mmHg a bad prognostic factor? Where did this number come from? Please share the evidence.
Perfect is the enemy of good. IMHO, the new PE classification is too granular to be clinically useful:
The evolution of acute pulmonary embolism classification (including the recently published 2026AHA/ACC/ACCP/ACEP/CHEST/
SCAI/SHM/SIR/SVM/SVN Guideline):
#foamed #foamcc #meded #Medsky #emimcc
Albumin (A) replacement therapy in septic shock
In a multicenter RCT, 440 pts w septic shock were treated w A aiming to keep serum A > 3.0 g/dL or w standard fluid therapy. 90-day mortality did not differ between the A group (43.3%) & controls (45.9%)
jamanetwork.com/journals/jam...
Mom of 7-year-old hospitalized with measles encephalitis: "I still wouldn’t have given my son the vaccine"
#PublicHealth #Medsky
www.independent.co.uk/news/health/...
Mom of 7-year-old hospitalized with measles encephalitis: "I still wouldn’t have given my son the vaccine"
#PublicHealth #Medsky
www.independent.co.uk/news/health/...
#foamed #foamcc #meded #Medsky #emimcc #albumin #sepsis
Albumin (A) replacement therapy in septic shock
In a multicenter RCT, 440 pts w septic shock were treated w A aiming to keep serum A > 3.0 g/dL or w standard fluid therapy. 90-day mortality did not differ between the A group (43.3%) & controls (45.9%)
jamanetwork.com/journals/jam...
In science, the most beautiful theory can be slayed by an ugly fact. In medicine, a beautiful therapy can be killed by an ugly trial
Public Health message:
Obesity hypoventilation syndrome/obstructive sleep apnea (OSH/OSA) - Some thoughts:
The following are some issues I have frequently encountered in the management of patients with OSH/OSA (I will intentionally combine them herein for the sake of the discussion):
#Bronchoscopy:
Besides setting the peak pressure alarm to its maximum (~100cmH2O), do you use any specific ventilator settings during fiberoptic bronchoscopy (FB) in intubated patients?
The VentSetFib study showed that using specific "bronchoscopy-optimized" ventilator settings
ICU Secrets:
“If you aren’t escalating care, you should start de-escalating”...
The United States has the highest incarceration rate in the world: nearly 2 million people locked up in 1,566 state prisons, 98 federal prisons, 3,116 local jails, 1,277 juvenile correctional facilities, 133 immigration detention facilities, 80 Indian country jails etc
Each year in prison takes 2 years off an individual's life expectancy. With > 2 million people locked up, mass incarceration has shortened the overall U.S. life expectancy by 1.5-2.0 years
Happy Sunday!
The United States has the highest incarceration rate in the world: nearly 2 million people locked up in 1,566 state prisons, 98 federal prisons, 3,116 local jails, 1,277 juvenile correctional facilities, 133 immigration detention facilities, 80 Indian country jails etc
ICU Secrets:
“If you aren’t escalating care, you should start de-escalating”...
I try to talk to them, bring family at bedside, try different masks, some times a bit of anxiolytic or antipsychotic etc
Bronchoscopy-optimized settings: inspiratory flow ≤ 25 l/min, tidal volume = 5ml/kg, 1s ≤ inspiratory time ≤ 1.3s, respiratory frequency = 16 breaths/min, positive end-expiratory pressure = 5cmH2O
Kudos to the authors!
#foamed #foamcc #meded #Medsky #pulmsky #emimcc
during FB significantly ⬇️ serious adverse events (4% vs 96% in conventional). Events were driven by ventilatory failure due to pressure-alarm limitation, with lower delivered Vt (160 vs 400 mL; p<0.001) & minute ventilation (3.2 vs 7.2 L/min; p<0.001) under conventional settings