Gut microbes affect cognition during ageing
As mice age, changes in the microorganisms in their guts contribute to cognitive decline by altering signalling between the gut and brain.
www.nature.com/articles/d41...
Intergenerational Transmission of Metabolic Changes in Oocytes From Aged Mice
onlinelibrary.wiley.com/doi/10.1111/...
Impact of exercise-induced DNA damage repair on age-related muscle weakness and sarcopenia
👉 “exercise-induced enhancement of DNA repair [contributes to] maintaining mitochondrial health, preserving muscle stem cell function, and combating cellular senescence”
www.frontiersin.org/journals/gen...
Is #geroscience and #longevity for everyone, or just for a few? Podcast on the ethics of it all, with @agingdoc.bsky.social and Carolyn Ringel: www.youtube.com/watch?v=Tedu...
Boston’s Longevity Obsession: What Works and What’s Expensive BS
We're becoming more & more obsessed with living forever—but not all the treatments are created equal. What works, what doesn’t and whether optimizing every aspect of your life is really worth it.
www.bostonmagazine.com/news/2026/01...
How to Make Friends as an Adult
A practical guide for expanding your circle, with advice from sociable people.
www.nytimes.com/article/how-... @nytstyle.bsky.social
Glucagon-like peptide-1 medicines and cancer
www.nature.com/articles/s43...
Senate advances bills rejecting Trump’s efforts to slash research funding 🧪
The White House requested cuts of 40% or more at some agencies. But lawmakers from both parties are pushing to hold science spending relatively steady.
www.highereddive.com/news/senate-...
Irradiated cannabis might still harbour toxic fungi and residues, McGill study finds
Researchers raise concerns about possible health risks for vulnerable users, point to a need for better methods and safeguards
www.mcgill.ca/newsroom/cha...
Targeted delivery of genome editors in vivo
🧬"Targeted delivery promises to considerably expand the therapeutic applicability of genome editing, moving closer to the ideal of a precise ‘magic bullet’ that safely and effectively treats diverse genetic disorders." 🩺
www.nature.com/articles/s41...
👍⚕️
My friend Andrew Steele is building this:
The majority of poor health and deaths globally are caused by diseases that become common with age...
"But public policy has yet to catch up.. & longevity science is underappreciated, and underfunded
We exist to change that" 🧑⚕️⚕️
thelongevityinitiative.org
This company is developing gene therapies for muscle growth, erectile dysfunction, and “radical longevity”
💉 A small group of volunteers will receive multiple injections of the experimental treatments next month, says Unlimited Bio 👨🏻⚕️
t.co/hMdyfVk58W
Interrupting Prolonged Sitting Reduces Postprandial Glucose Concentration in Young Men With Central Obesity
👉 Interrupted prolonged sitting [3 min light walking or 1.5 minutes of moderate walking every 30 minutes] reduced postprandial glucose concentrations.
academic.oup.com/jcem/article...
People often ask me the same question:
“What’s the single most promising anti-aging measure coming in the next decade?”
If you care about where longevity medicine is truly heading, this one’s worth a look.
🔗https://www.instagram.com/reel/DRni2qQgNTS
Semaglutide versus caloric restriction-induced weight loss: insights into effects on skeletal muscle mass and function
"[suggests] loss of muscle function and mass during treatment is not unique to GLP-1RA pharmacology but rather reflects the biology of caloric restriction…"
x.com/agingdoc1/st...
My post from Founders Forum North America (NYC) 🗽
🔗 www.linkedin.com/posts/agingd... 🚀
AI Learns to Design the Human Body’s Most Elusive Proteins
🤩 Summary: A new machine learning method has achieved what even AlphaFold cannot… their ever-changing structures have defied traditional AI prediction models.
neurosciencenews.com/ai-protein-d...
Scientists make embryos from human skin DNA for first time
www.bbc.com/news/article...
This AI tool predicts your risk of 1,000 diseases — by looking at your medical records
Trained on 400,000 medical records, the system can predict risks 20 years in advance — plus, how AIs could make you more likely to cheat
nature.com/articles/d41...
@shamini.bsky.social 🧪
Sex-specific longitudinal reversal of aging in old frail mice
www.aging-us.com/article/2063...
The evolution of cancer and ageing: a history of constraint
www.nature.com/articles/s41...
@erictopol.bsky.social is right — we haven’t rigorously validated gerotherapeutics in humans, and even if we did, we’d need to show they also compress morbidity.
Some source for optimism: for some animal models, better healthspan can track increased longevity.
pmc.ncbi.nlm.nih.gov/articles/PMC...
Fraudulent Scientific Papers Are Rapidly Increasing, Study Finds
A statistical analysis found that the number of fake journal articles being churned out by “paper mills” is doubling every year and a half. 🤯
www.nytimes.com/2025/08/04/s...
See you there!
👍
You’re not on X anymore right (making sure I didn’t miss you there for cross-posting)?
Keep up the great work Laura!
Healthy Lifestyle Can Help People at Risk for Dementia, Study Finds
The study found that a combination of exercise, healthy diet and other behaviors led to cognitive benefits…
www.nytimes.com/2025/07/28/h...
DNA Methylation Ageing Atlas Across 17 Human Tissues
👉“Our open-access atlas provides a foundational resource for dissecting the molecular architecture of human aging and identifying testable targets for intervention..”
@nireynon.bsky.social and coauthors
www.biorxiv.org/content/10.1...
Editorial: Resilience in aging
@drlaurahaynes.bsky.social and coauthors
www.frontiersin.org/journals/agi...
