Max Planck Institute of Molecular Cell Biology and Genetics's Avatar

Max Planck Institute of Molecular Cell Biology and Genetics

@mpi-cbg.de

How do cells form tissues? Our research program spans the scales from molecules to organisms. News from the Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG) in Dresden, Germany. Impressum: https://www.mpi-cbg.de/impressum

8,382
Followers
455
Following
206
Posts
23.10.2023
Joined
Posts Following

Latest posts by Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de

Post image

Apply now for the Max Planck Foundation start-up school and learn how to transform research into real-world application. June 3-5 @mpi-cbg.de! startupinitiative.maxplanckfoundation.org/en/start-up-...

06.03.2026 13:36 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
Human liver cholangiocyte organoids capture the heterogeneity of in vivo liver ductal epithelium Human liver ductal epithelium is morphologically, functionally, and transcriptionally heterogeneous. Understanding the impact of this heterogeneity ha…

Original Publication: www.sciencedirect.com/science/arti...

05.03.2026 09:28 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
A stride towards a better liver model By altering the growth environment, the Huch lab at MPI-CBG has developed a liver model that extensively mimics the heterogeneity of the real organ.

By altering the growth environment, the group of @merihuchlab.bsky.social @mpi-cbg.de with first authors Javier Bregante & Flaminia Kaluthantrige has developed a liver model that extensively mimics the heterogeneity of the real organ. @cp-cellreports.bsky.social. www.mpi-cbg.de/news-outreac...

05.03.2026 09:27 πŸ‘ 7 πŸ” 3 πŸ’¬ 1 πŸ“Œ 1
Preview
Die Genschere in Dresden, 26.3.2026 bis 29.3.2026 - CRISPR-Whisper Die β€žCRISPR-Roadshowβ€œ ist ein Projekt des Forschungskonsortiums SPP2141, mit dem Wissenschaft fΓΌr jedermann verstΓ€ndlich und erlebbar wird. Der SPP2141 ist eine Gruppe von 20 Forschungslaboren, die vo...

The public event "CRISPR Gene scissors in Dresden" is taking place March 26 to 29. The "CRISPR-Roadshow" is teaming up with partners @mpi-cbg.de, @tudresden.bsky.social, and @crtd-tud.bsky.social for a wide range of activities on the CRISPR/Cas method. www.crispr-whisper.de/2025/10/01/d...

03.03.2026 15:01 πŸ‘ 5 πŸ” 3 πŸ’¬ 0 πŸ“Œ 1

🦜 The genomes of fours species in this study were sequenced and assembled at @mpi-cbg.de. The Cell Technology Facility extracted the relevant RNAs for the functional analyses. 🦜

27.02.2026 14:49 πŸ‘ 9 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

Mini organs in space: Research project of the @tudresden.bsky.social together with @mpi-cbg.de investigates the effects of weightlessness on liver tissue. The liver organoids for the project come from Meritxell Huch's research group @merihuchlab.bsky.social. www.mpi-cbg.de/news-outreac...

26.02.2026 15:34 πŸ‘ 8 πŸ” 1 πŸ’¬ 0 πŸ“Œ 1
Post image

Nikola Sadovek in @haharrington.bsky.social group & Daniel McGinnis @princetonupress.bsky.social, solved a 38-year-old mathematical puzzle by finding a precise rule for when a point, line, or plane can simultaneously intersect a whole family of convex shapes. www.sciencedirect.com/science/arti...

25.02.2026 15:24 πŸ‘ 7 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
Spatially Informed Autoencoders for Interpretable Visual... We introduce spatially informed variational autoencoders (SI-VAE) as self-supervised deep-learning models that use stochastic point processes to predict spatial organization patterns from images....

Our work @tudresden.bsky.social @csbdresden.bsky.social @mpi-cbg.de @scadsai.bsky.social fuses representation learning with spatial statistics @iclr-conf.bsky.social enabling #AI for spatial localization patterns: openreview.net/forum?id=09Y...

25.02.2026 14:42 πŸ‘ 8 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
Post image

LiSyM Status Seminar-2026 is hold right now in Dresden! We are happy to share our latest results in liver #lipidomics and #proteomics with colleagues @mpi-cbg.de and other researches from Liver System Medicine Consortium @lisymcancer.bsky.social. Together we are a very strong team!πŸ’ͺ

25.02.2026 14:46 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Post image

Join us in Vienna for the biggest international 'FISH' meeting in 2026! No matter which fish is your favorite model - zebrafish, medaka, killifish, cavefish, Danionella, cichlids, stickleback, you name them...- this meeting is for you!

www.ezm2026.org

Abstract submission deadline is March 15th.

23.02.2026 20:06 πŸ‘ 27 πŸ” 16 πŸ’¬ 3 πŸ“Œ 3
Post image

Congratulations to our colleague Dr. Vannur Garikapati on new step in career development! Following successful postdoctoral research in lipidomics @mpi-cbg.de he'll be building new mass spectrometry Facility at the Medical School Uni Bielefeld. We are very proud of you, Vannur! Stay in touch❀️

22.02.2026 11:39 πŸ‘ 4 πŸ” 2 πŸ’¬ 0 πŸ“Œ 1
Post image Post image Post image Post image

As the President of the Beer Committee (yes...), I have moved the quest to #MakeBeerHourGreatAgain to the next level. By executive order, the #CzechPolka "Roll Out the Barrels" becomes the official beer #anthem. #Starobrnobitter Lots of foam, room for improvement. But it went fast... ❀️ @mpi-cbg.de

20.02.2026 19:49 πŸ‘ 48 πŸ” 7 πŸ’¬ 4 πŸ“Œ 0
COMBINING FLUORESCENCE MICROSCOPY WITH OPTICAL TWEEZERS TO SHINE LIGHT ON DNA AND CHROMOSOMES. Erwin Peterman. Vrije Universiteit Amsterdam. Saturday 21 February 2026 - 4:00 PM - Room 303/304, Biological Fluorescence Symposium.

A PROTEIN-DNA SURFACE HYDROGEL MECHANICALLY REINFORCES THE CELL NUCLEUS AND PROTECTS THE GENOME. Ramesh Adakkattil. MPI-CBG (Von Appen lab). Sunday 22 February 2026 - 4:00 PM - Room 201/202/203, Platform: Condensates from Biophysics to Disease I.

COMBINING FLUORESCENCE MICROSCOPY WITH OPTICAL TWEEZERS TO SHINE LIGHT ON DNA AND CHROMOSOMES. Erwin Peterman. Vrije Universiteit Amsterdam. Saturday 21 February 2026 - 4:00 PM - Room 303/304, Biological Fluorescence Symposium. A PROTEIN-DNA SURFACE HYDROGEL MECHANICALLY REINFORCES THE CELL NUCLEUS AND PROTECTS THE GENOME. Ramesh Adakkattil. MPI-CBG (Von Appen lab). Sunday 22 February 2026 - 4:00 PM - Room 201/202/203, Platform: Condensates from Biophysics to Disease I.

Find Erwin Peterman (@vuamsterdam.bsky.social) speaking on the virtues of combining fluorescence microscopy with optical tweezers on Saturday 4:00 PM, Room 303/304.

On Sunday, 4:00 PM, Room 201/202/203, Ramesh Adakkattil of the Von Appen lab (@mpi-cbg.de) speaks on the protein-DNA surface hydrogel.

16.02.2026 15:19 πŸ‘ 1 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
Post image

2026 marks the 25th Anniversary of @mpi-cbg.de in Dresden. We invite all Alumni to reconnect and celebrate 25 years of science together August 24-25. Sign up, if you would like to receive further updates, formal registration will follow: www.mpi-cbg.de/25th-anniver...

18.02.2026 16:20 πŸ‘ 17 πŸ” 6 πŸ’¬ 0 πŸ“Œ 2
Preview
Laser Capture Microdissection for Quantitative Shotgun Lipidomics In tissues or organs, lipids are not distributed uniformly. While staining with dyes or antibodies locates histological features at cryosections of tissues, it does not elucidate their molecular compo...

Our chapter "Laser Capture Microdissection for Quantitative Shotgun Lipidomics" is out in Methods in Molecular Biology @springernature.com ! We're delighted to share expertise and protocols in lipid analysis by mass spectrometry @mpi-cbg.de with the broad scientific community.

15.02.2026 20:30 πŸ‘ 6 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
Video thumbnail

Giulio from the group of TΓΌrkΓΌ Γ–zlΓΌm Γ‡elik talks on mathematical structures during our current coffee chalk talk series @csbdresden.bsky.social @math-mpicbg.bsky.social to promote knowledge exchange between disciplines.

06.02.2026 13:44 πŸ‘ 15 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0

Electrifying story from @ritamateus.bsky.social lab. @mpi-cbg.de @poldresden.bsky.social

05.02.2026 09:56 πŸ‘ 27 πŸ” 4 πŸ’¬ 1 πŸ“Œ 0
Preview
Injury-induced electrochemical coupling triggers organ growth Organ repair and growth rely on coupling tissue-wide membrane depolarization with intracellular proliferative signaling.

New paper alert!🀩Super proud that our story led by superstar postdocs @liujinghui.bsky.social and @nerlielisa.bsky.social is finally out! We found how electrical signals are key for promoting organ regenerative growth!!! A thread 🧡https://www.science.org/doi/10.1126/sciadv.aec0687

05.02.2026 09:33 πŸ‘ 119 πŸ” 32 πŸ’¬ 6 πŸ“Œ 4
Video thumbnail

βš‘πŸ‘©β€πŸ”¬Electrical signals are key for promoting organ regenerative growth, a new study!

Out now in Science Advances, from the Mateus group @ritamateus.bsky.social at PoL and @mpi-cbg.de along with the lab of Frank JΓΌlicher @mpipks.bsky.social

Read the news here: tud.link/7jzptz
Video:©️ Mateus group

05.02.2026 10:02 πŸ‘ 47 πŸ” 15 πŸ’¬ 0 πŸ“Œ 2
portrait of Nagaraja Chappidi

portrait of Nagaraja Chappidi

We welcome new research group leader Nagaraja Chappidi! He joins the @mpi-cbg.de to explore how cells regulate DNA replication and repair. www.mpi-cbg.de/news-outreac...

03.02.2026 15:26 πŸ‘ 22 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
Post image

Just in time for Friday, the next image from our annual PoL Photo Competition πŸ“Έ

πŸ‘¨β€πŸ”¬ πŸ”¬Β©οΈ This #microscopy image was taken by Shuzo Kato, a PhD student in the BruguΓ©s lab @brugueslab.bsky.social @mpi-cbg.de

πŸ” Caption: The mitotic spindle in a zebrafish embryo under oxygen depletion (DCX-GFP).

30.01.2026 14:13 πŸ‘ 15 πŸ” 3 πŸ’¬ 0 πŸ“Œ 1
Video thumbnail

Really excited to share our new paper in @nature.com! We uncovered how a physical instability of the cytoplasm coupled with the cell cycle drives cytoplasmic partitioning in early embryos #zebrafish #drosophila. Read more in this🧡 www.nature.com/articles/s41... 🀩
@poldresden.bsky.social @mpi-cbg.de

28.01.2026 16:10 πŸ‘ 204 πŸ” 67 πŸ’¬ 4 πŸ“Œ 10
Post image

πŸŽ‰Exciting new findings out in @nature.com today by the BruguΓ©s lab! @brugueslab.bsky.social @mpi-cbg.de

πŸ‘¨β€πŸ”¬ The authors describe how physical instability of the cytoskeleton works with the cell cycle to drive organization in the embryo during early development

Read our press release: tud.link/kctu4s

28.01.2026 16:17 πŸ‘ 21 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0

The spring call for the ELBE Postdoctoral Fellows Program is open now: www.csbdresden.de/join-us/as-a.... Join the @csbdresden.bsky.social for a fully funded fellowship. @mpi-cbg.de @mpipks.bsky.social

28.01.2026 10:48 πŸ‘ 17 πŸ” 12 πŸ’¬ 2 πŸ“Œ 2
Post image

πŸŽ“ Congratulations to Jonas PΓΆhls on successful PhD thesis defense . β€œThe Dark Proteome: The extent and impact of phenotypic mutations in prokaryotes” is a challenging interlaboratory work between @tothpetroczylab.bsky.social & Shevchenko lab @mpi-cbg.de @csbdresden.bsky.social Proud of you, Jonas!

27.01.2026 13:48 πŸ‘ 12 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
event poster with green background

event poster with green background

Join the GROW@Dresden 2026 event March 26-27 @tudresden.bsky.social and @mpi-cbg.de and register here: plan.events.mpg.de/event/588/ The event is for all students of underrepresented gender identities in mathematics, especially women, who want to explore graduate programs and research opportunities.

23.01.2026 15:36 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

Congratulations to Rashmi and Karolina and also to the technology development studio of the MPI-CBG without whom the screen would not have been possible.
If you are interested in high-content screening in organoid models, you may want to take a look.

22.01.2026 14:04 πŸ‘ 25 πŸ” 10 πŸ’¬ 0 πŸ“Œ 0

@kuodyte.bsky.social

21.01.2026 16:35 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
High-content screening of organoids reveals the mechanisms of human pancreas acinar specification Keshara et al. conducted a high-content screen on pancreas organoids that identified 54 compounds affecting differentiation or morphogenesis. After validating 11 compounds, they focus on Gsk3A/B inhib...

Publication in @cp-cellstemcell.bsky.social: www.cell.com/cell-stem-ce...

21.01.2026 16:33 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Preview
Making human pancreatic acinar cells Dresden researchers develop novel methods to create acinar cells, which are involved in the formation of pancreatic cancer.

The group of @anne-grapin.bsky.social developed methods to create functional acinar cells, which are involved in the formation of pancreatic cancer. Rashmiparvathi Keshara, Karolina Kuodyte, and the TDS facility used image-based screen & robust analysis pipeline. www.mpi-cbg.de/news-outreac...

21.01.2026 16:33 πŸ‘ 14 πŸ” 6 πŸ’¬ 2 πŸ“Œ 2