Ayele Argaw-Denboba's Avatar

Ayele Argaw-Denboba

@denbobalab

Gut microbiota, Developmental metabolism, Epigenetic inheritance|Group Leader@MPI-IE

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Latest posts by Ayele Argaw-Denboba @denbobalab

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Paternal microbiome perturbations impact offspring fitness Nature - Disturbances in the gut microbiota of male mice manifest as fitness defects in their offspring by affecting plancenta function, revealing a paternal gut–germline axis.

As an "EIPOD" interdisciplinary postdoc in @jamiehackett.bsky.social and our lab, @denbobalab.bsky.social found that "Paternal microbiome perturbations impact offspring fitness" (2024): antibiotic treatment of male mice led to low birth weight & higher mortality in offspring

www.nature.com/artic...

19.12.2024 14:00 👍 15 🔁 6 💬 1 📌 1
Rob Martienssen (CSHL) and Yoichi Shinkai (Riken)

Rob Martienssen (CSHL) and Yoichi Shinkai (Riken)

Hiten Madhani (UCSF): »Epigenetic memory over geological timescales«

Hiten Madhani (UCSF): »Epigenetic memory over geological timescales«

Valérie Hilgers and her lab investigate the molecular mechanisms underlying neuron-specific RNA signatures. The lab aims to understand how RNA processing affects neuronal development and function

Valérie Hilgers and her lab investigate the molecular mechanisms underlying neuron-specific RNA signatures. The lab aims to understand how RNA processing affects neuronal development and function

Ayele Denboba: »Modelling epigenetic inheritance through gut microbiota-germline interactions« /// The lab aims to decipher the regulatory role of gut microbiota in gametogenesis, embryogenesis, epigenetic inheritance mechanisms, and identify microbiome-sourced metabolites that regulate chromatin functions.

Ayele Denboba: »Modelling epigenetic inheritance through gut microbiota-germline interactions« /// The lab aims to decipher the regulatory role of gut microbiota in gametogenesis, embryogenesis, epigenetic inheritance mechanisms, and identify microbiome-sourced metabolites that regulate chromatin functions.

The Epigenetics Meeting in Freiburg is known for being pretty packed. Thus, right after the keynote by Patrick Cramer, we continued with Rob Martienssen, Hiten Madhani @hitenmadhani.bsky.social, Valérie Hilgers, Ayele Denboba @denbobalab.bsky.social as well as Yoichi Shinkai from RIKEN.

07.12.2024 17:04 👍 3 🔁 1 💬 1 📌 0

Highly recommend - exciting project and best mentor to grow as a scientist!👇

02.12.2024 12:24 👍 5 🔁 0 💬 0 📌 0
Advert detailing a postdoctoral scientist position at EMBL Rome. Contact: jamie.hackett@embl.it

Advert detailing a postdoctoral scientist position at EMBL Rome. Contact: jamie.hackett@embl.it

Postdoc positions in epigenetics!

We have several opportunities to investigate big picture questions on (epi)genome function & mechanisms

Based @embl.org near Rome (Italy), we offer full scientific support/facilities, training & funding. Also...☀️🏛️🍕🏖️

See👇or contact me for other options. Pls RS

02.12.2024 11:32 👍 81 🔁 56 💬 0 📌 10

Starter packs are fab, but skew towards established folks

Cue intros into all the amazing people in our lab… give them a follow 🚶

First up Marzia Munafo. Leading a spectacular oocyte epigenomics project (watch this space 👀) and science illustrator extraordinaire. Check out the beautiful works 👇👇

28.11.2024 21:56 👍 34 🔁 7 💬 2 📌 6