No disciplinarity without interdisciplinarity!
04.03.2026 18:51
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No disciplinarity without interdisciplinarity!
In early-2025 I was reeling from a ‘scored fundable’ grant application that was not funded. I really believed in this grant and knew the ideas were good but the review panel just weren’t into the project and there nothing more I could do. That’s science, but it hurts. (1/8)
Congratulations to Prof Bart Vanhaesebroeck, Prof @christophertape.bsky.social & Team REWIRE-CAN on securing $25m in @cancergrand.bsky.social funding to take on the challenge of rewiring cancer cells.
#CancerGrandChallenges @uclmedsci.bsky.social
www.ucl.ac.uk/news/2026/ma...
Interested in joining a dynamic, interdisciplinary research department? A call is open for Group Leaders at the UCL Laboratory for Molecular Cell Biology.
Please submit your expression of interest by April 13, 2026.
Further details here: www.ucl.ac.uk/work-at-ucl/...
New from @dev-journal.bsky.social: we're launching a new initiative and hiring Preprint Editors to help navigate the growing world of preprints in developmental & stem cell biology
Join our community & shape the future of research
journals.biologists.com/dev/article/...
One of the main stories of my postdoc is finally out! It builds on an intuition from my early days in omics data analysis: our signaling pathways are simply too small, underrepresenting cellular complexity after stimulation. Something obvious, yet surprisingly hard to quantify.
“Helsinki hasn’t registered a single traffic-related fatality in the past year…Citing data that shows the risk of pedestrian fatality is cut in half by reducing a car’s speed from 40 to 30km/hr, city officials imposed the lower limit in most of Helsinki’s residential areas and city center in 2021.”
This spoof is fantastic, not least for the aging choices they’ve made for the tech broligarchs. youtu.be/zdkBUuWCZg4?...
This is such a great and timely survey on author's perception of peer review vs AI scientific review. A collaboration between @reviewcommons.org and @qedscience.bsky.social. The geek in me would have liked to see the distributions in the response scores ;). link.springer.com/article/10.1...
AMICI v1.0.0 is here.
Big milestone release:
🧹 MATLAB interface officially retired
⚡ Brand-new JAX/diffrax interface
🧬 First support for PEtab v2
major step toward a cleaner, more future-proof ecosystem.
github.com/AMICI-dev/AM...
Our internal organs are evolutionary marvels. New technologies are transforming our understanding of the evolution of vertebrate organs. You can find more by reading here:
rdcu.be/e5EgU
#EvoBio #EvoDevo 🐟🦎🐢🦇🐊🦜
Some thoughts on AI and math, inspired by “First Proof”: www.daniellitt.com/blog/2026/2/...
Rewiring of oncogenic signaling in #DrugResistance is a moving target. In our new study, we used biophysical phosphoproteomics to investigate #BRAF mutant cancer, linking phosphorylation changes to protein function and #MolecularMechanisms through #Multi-Omics integration.
tinyurl.com/funsignaling
Hey journals, if you want reviewers, reconsider the “no AI under any circumstances” policy. I’m happy not to paste unpublished work into the algorithmic equivalent of a public restroom wall, but broad technoskeptic edicts about how I manage my time are unlikely to inspire more volunteering.
Not all those who wander are lost.
AlphaGenome is out in @nature.com today along with model weights! 🧬
📄 Paper: www.nature.com/articles/s41...
💻 Weights: github.com/google-deepm...
Getting here wasn’t a straight path. We discussed the story behind the model, paper & API in the following roundtable: youtu.be/V8lhUqKqzUc
I remember seeing some pretty impressive demos from Adobe for generative AI for vector graphics.
“Everything we know about skin has been learned from so-called scientific studies funded by large corporations who have a financial stake in keeping our musculature covered in an unnecessary layer of man-made flesh,” said Health and Human Services Secretary Robert F. Kennedy Jr.
New paper alert!🤩Super proud that our story led by superstar postdocs @liujinghui.bsky.social and @nerlielisa.bsky.social is finally out! We found how electrical signals are key for promoting organ regenerative growth!!! A thread 🧵https://www.science.org/doi/10.1126/sciadv.aec0687
Our new paper: Entropy Sorting Feature Selection (ESFS)
A computational framework for gene selection from single cell data that extracts biological signals in noisy data while avoiding artefacts from conventional dimensionality reduction
A thread
www.biorxiv.org/content/10.6...
Person standing outside next to a building wearing a red jacket
Meet Leonie Johanna Lorenz 🇩🇪, a Predoctoral Fellow at EMBL-EBI who is bringing mathematical modelling to microbes.
Find out more about how Leonie’s passion for modelling patterns extends from bacterial evolution to sewing 🧵
www.ebi.ac.uk/about/news/p...
We Are hiring!! 👨💻👩💻 CALM's new Data and Systems Steward Role is live 🎉https://crick.wd3.myworkdayjobs.com/External/job/London/Data-and-Systems-Steward_R2551 closing date 8th Feb!
One of the less advertised advantages of using LLMs for writing is that, when OneDrive decides your past few days of work were a mistake, the text still exists somewhere.
Sorry to be characteristically German, but Stoßlüften depends on good insulation and substantial thermal mass, so cold air is reheated quickly. In much of the UK and US, where buildings are effectively made of cardboard, the idea is more wishful thinking than what physics practically allows.
We are recruiting a Postdoc in computational biology, together with @mariasecrier.bsky.social
4yr, fully funded by @cancerresearchuk.org, ideal for Postdocs wanting to develop their independence
Applications open now: www.imperial.ac.uk/jobs/search-...
View from the hotel room
Poster session 2024, with Valentina Boeva, Constantin Ahlmann-Eltze and others
Wednesday afternoon hike incl. swim in the mountain river
Another view from the hotel room
Apply for the Ascona workshop "Statistical and AI methods for multi-modal multi-scale modeling of biological systems", 28 Jun-3 Jul 2026 on Monte Verità, Lago Maggiore at the foot of the Swiss Alps.
ascona2026.sciencesconf.org
Didn’t they say they want the gilded age back? So this seems very much on message en.wikipedia.org/wiki/Radium_...
🚀 New preprint! Meet ORIGAMI: Mapping cancer cell state heterogeneity and plasticity, predicting and steering therapy-induced trajectories to rationalize genotype-agnostic combination strategies with only two physical metrics (cell surface area and volume)
www.researchsquare.com/article/rs-8...
Looking to start your lab in generative biology / AI?
Come join us at the @sangerinstitute.bsky.social
Sanger is core-funded so you can generate data at scale to train the next generation of models and understanding. Design/Engineering/Chemistry/Proteins/Pathways!
pls RT
tinyurl.com/GenGenFaculty
