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Center for Craniofacial Molecular Biology of USC

@ccmb.usc.edu

Center for Craniofacial Molecular Biology - Herman Ostrow School of Dentistry of USC https://linktr.ee/ccmb_usc

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20.03.2025
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Latest posts by Center for Craniofacial Molecular Biology of USC @ccmb.usc.edu

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It's almost time for the 18th annual Ostrow Research Day on April 8th in the USC Hotel Ballroom. Please don't forget to register! #CCMBUSC #USCResearch #ResearchDay
dentistry.usc.edu/research-day...

12.03.2026 20:37 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Spatial transcriptomics of the mouse temporomandibular joint (TMJ) using seqFISH, from the dataset "Spatial Transcriptomics of Mouse CFA-induced TMJ arthritis" https://doi.org/10.25550/8Q-3KAR

Spatial transcriptomics of the mouse temporomandibular joint (TMJ) using seqFISH, from the dataset "Spatial Transcriptomics of Mouse CFA-induced TMJ arthritis" https://doi.org/10.25550/8Q-3KAR

New data: Spatial transcriptomics (using seqFISH) reveals a fibroblast-immune microenvironment remodeling pathway in CFA-induced TMJ arthritis in mice. PI: Jian-Fu Chen (University of Southern California)

doi.org/10.25550/8Q-...

05.03.2026 17:56 ๐Ÿ‘ 2 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Ahead of the upcoming #Lymphatics GRC meeting, for #JEM_Spotlight this month I would like to highlight this 2025 study from Jian-Fu Chen @ccmb.usc.edu where his lab identifies lymphatic vessels in the skull periosteum ๐Ÿง  Take a look here: doi.org/10.1084/jem....

20.02.2026 18:45 ๐Ÿ‘ 1 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Dr. Amy Merrillโ€™s lab establishes a new mouse model to better understand the cellular and molecular mechanisms underlying anterior displacement of the articular disc in temporomandibular disorders (TMDs) in their latest publication in JBMR Plus. ๐Ÿงช #CCMBUSC #USCResearch #TMDs

09.02.2026 21:01 ๐Ÿ‘ 3 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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New in JBMRยฎ Plus: A reproducible mouse model of TMJ anterior disc displacement โ€” offering a powerful platform to study TMD mechanisms + potential therapeutic targets.

Read the openโ€‘access article: doi.org/10.1093/jbmr...

29.01.2026 20:04 ๐Ÿ‘ 1 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Flyer for the FaceBase 2026 Community Forum
Arlington, VA on May 4 & 5, 2026
Advances in data reuse, integration, and AI-ready biomedical research in dental, oral, craniofacial, inner ear and related research.

Flyer for the FaceBase 2026 Community Forum Arlington, VA on May 4 & 5, 2026 Advances in data reuse, integration, and AI-ready biomedical research in dental, oral, craniofacial, inner ear and related research.

Registration and Call for Abstracts are open for the FaceBase 2026 Community Forum!

Advances in data reuse, integration, and AI-ready biomedical research in dental, oral, craniofacial, inner ear and related research.

๐Ÿ“… May 4-5, 2026
๐Ÿ“ Arlington, VA (also via Zoom)

Register: bit.ly/FBForum2026

06.02.2026 18:28 ๐Ÿ‘ 3 ๐Ÿ” 2 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 1
Spatial Transcriptomics of TMJ Reveals a Remodeling Fibroblastโ€Immune Microenvironment Driving Arthritis Pain You have to enable JavaScript in your browser's settings in order to use the eReader.

Jianfu Chen's lab uses spatial transcriptomics to map the diverse cell types in the temporomandibular joint (TMJ) and uncover a microenvironment involved in arthritic pain in their latest publication in Advanced Science. ๐Ÿงช #CCMBUSC #USCResearch #FightOn #Science #TMJ

05.02.2026 18:13 ๐Ÿ‘ 3 ๐Ÿ” 2 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Picture of Dr. Jianfu "Jeff" Chen with his arms crossed. Congratulations on his promotion to the rank of Professor at the Herman Ostrow School of Dentistry of the University of Southern California.

Picture of Dr. Jianfu "Jeff" Chen with his arms crossed. Congratulations on his promotion to the rank of Professor at the Herman Ostrow School of Dentistry of the University of Southern California.

CCMB would like to congratulate Dr. Jianfu โ€œJeffโ€ Chen on his promotion to Professor at the Herman Ostrow School of Dentistry of USC!

26.01.2026 18:14 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Save the Dates for the 2026 FaceBase Community Forum in Arlington, VA on: May 4 & 5 2026! For updates, go to:https://bit.ly/FBForum2026

Save the Dates for the 2026 FaceBase Community Forum in Arlington, VA on: May 4 & 5 2026! For updates, go to:https://bit.ly/FBForum2026

Save the dates for the next FaceBase Community Forum: May 4 & 5 2026 in Arlington, VA. More details coming soon!

www.facebase.org/community/an...

20.01.2026 17:52 ๐Ÿ‘ 2 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Screenshot of the FaceBase Virtual Bootcamp - Fall 2025: Rob Schuler is presenting a slide about how FaceBase data is ready for Reuse, Reproducibility and (Re)analysis.

Screenshot of the FaceBase Virtual Bootcamp - Fall 2025: Rob Schuler is presenting a slide about how FaceBase data is ready for Reuse, Reproducibility and (Re)analysis.

Missed the FaceBase Bootcamp? No worries!
Catch up with recordings and slides covering data discovery, submissions, and DMS plans:
๐ŸŽฅ www.facebase.org/community/tr...

#FaceBase #DataSharing #CraniofacialResearch #NIH #DentalResearch #DataReuse #FAIRdata #DataScience

12.11.2025 19:41 ๐Ÿ‘ 4 ๐Ÿ” 2 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Rucha Bapat, Janet Moradian-Oldak, and Gayathri Visakan of the Center for Craniofacial Molecular Biology of USC at Enamel 11, an international conference held in France earlier this month. Not only did Rucha and Gayathri both present their research on ameloblastin and enamel formation, they also both received Young Investigator Travel Awards.

Rucha Bapat, Janet Moradian-Oldak, and Gayathri Visakan of the Center for Craniofacial Molecular Biology of USC at Enamel 11, an international conference held in France earlier this month. Not only did Rucha and Gayathri both present their research on ameloblastin and enamel formation, they also both received Young Investigator Travel Awards.

Congratulations to Rucha Bapat and Gayathri Visakan! In addition to being invited to present their research on ameloblastin and enamel formation, they were also awarded Young Investigator Travel Awards at #Enamel11, a conference held in France earlier this month. #CCMBUSC #CraniofacialResearch

29.10.2025 23:47 ๐Ÿ‘ 2 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
OR DENTAL, ORAL AND CRANIOFACIAL RESEARCHERS, CLINICIANS AND STUDENTS

FACEBASE BOOTCAMP

(FOR USERS AND CONTRIBUTORS)

LEARN HOW TO MAKE THE MOST OF THE FACEBASE RESOURCE AND BEST PRACTICES FOR MANAGING AND SHARING DATA

Wed, November 5 1:00 pm - 4:00 pm Eastern/ 10:00 am - 1:00 pm Pacific

Online Event

Learn more and register at:

facebase.org/community/training/

OR DENTAL, ORAL AND CRANIOFACIAL RESEARCHERS, CLINICIANS AND STUDENTS FACEBASE BOOTCAMP (FOR USERS AND CONTRIBUTORS) LEARN HOW TO MAKE THE MOST OF THE FACEBASE RESOURCE AND BEST PRACTICES FOR MANAGING AND SHARING DATA Wed, November 5 1:00 pm - 4:00 pm Eastern/ 10:00 am - 1:00 pm Pacific Online Event Learn more and register at: facebase.org/community/training/

๐Ÿ“ฃ Our next virtual bootcamp, tailored for both users and data contributors, is coming up next week: Wednesday, November 5th! Whether you're a seasoned user of FaceBase or looking to contribute data for the first time, this event is for you!

www.facebase.org/community/tr...

28.10.2025 00:48 ๐Ÿ‘ 1 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Yang Chai installed as dean of the Herman Ostrow School of Dentistry of USC The clinician-scientist is also the schoolโ€™s associate dean of research and served as interim dean.

This week we officially welcomed Dr. Yang Chai as dean of the Herman Ostrow School of Dentistryโ€”renowned scientist, visionary leader, and Trojan through and through.

10.10.2025 23:00 ๐Ÿ‘ 2 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 1
Peng Chen of the Center for Craniofacial Molecular Biology (CCMB) of the University of Southern California's Herman Ostrow School of Dentistry with his plaque for winning first place in the post-doctoral category of the American Association for Dental, Oral, and Craniofacial Research (AADOCR) Hatton Competition for his oral presentation on craniosynostosis and coronal suture regeneration

Peng Chen of the Center for Craniofacial Molecular Biology (CCMB) of the University of Southern California's Herman Ostrow School of Dentistry with his plaque for winning first place in the post-doctoral category of the American Association for Dental, Oral, and Craniofacial Research (AADOCR) Hatton Competition for his oral presentation on craniosynostosis and coronal suture regeneration

๐Ÿง  Congratulations to Peng Chen on receiving his plaque for winning 1st place (Post-Doc) in the AADOCR Hatton Competition! His talk, โ€œSuture-Dura Interaction Supports Coronal Suture Regeneration in Craniosynostosis,โ€ earned top honors earlier this year. #CCMBUSC #Craniosynostosis #AADOCR #Research

10.10.2025 18:37 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Unmasking cancerโ€™s hidden nerve route with patient-derived organoids Chan et al. show that enteric neurons influence lipid metabolism in gastric cancer organoids, affecting dependencies on key enzymes. Using CRISPR screening and metabolic analysis, their work highlights how microenvironmental signals impact tumor metabolism and potential treatment targets in gastric cancer.

Unmasking cancerโ€™s hidden nerve route with patient-derived organoids

06.10.2025 23:36 ๐Ÿ‘ 2 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Heliya Ziaei stands in front of the Center for Craniofacial Molecular Biology of USC door with her certificate for winning first place in the Student Competition at the AADOCR Southern California Section Research Symposium

Heliya Ziaei stands in front of the Center for Craniofacial Molecular Biology of USC door with her certificate for winning first place in the Student Competition at the AADOCR Southern California Section Research Symposium

๐ŸŽ‰ Congratulations to Heliya Ziaei for winning first place in the Student Competition at the 2025 @aadocr.bsky.social Southern California Section Research Symposium, where she presented on the important role of Kdm6b in tooth root development earlier this year.

03.10.2025 18:37 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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If you are attending the poster session at the Society for Craniofacial Genetics and Developmental Biology meeting this year, make sure to stop by and say hi to Rob and Alejandro at the FaceBase poster and demo! @scgdb.bsky.social

30.09.2025 18:38 ๐Ÿ‘ 2 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Featured resource: Facebase - the Node Our โ€˜Featured resourceโ€™ series aims to shine a light on the resources that support our research โ€“ the unsung heroes of the science world. In this post, we learn about the data and functionalities avai...

Featured resource: Facebase

In this post, we learn about the data and functionalities available at Facebase @facebase.bsky.social, and hear about new initiatives they are developing.

thenode.biologists.com/featured-res...

25.09.2025 10:35 ๐Ÿ‘ 6 ๐Ÿ” 3 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 1

Check out our latest publication on lymphatic vessel identification by Jeff Chen's lab! ๐Ÿงช #CCMBUSC #Science #Lymphatics #USCResearch

29.09.2025 18:33 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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President Kim, Provost, deans, former Governor Schwarzenegger + democracy โ€” hear why your voice matters. #DemocracyDay

15.09.2025 17:06 ๐Ÿ‘ 7 ๐Ÿ” 7 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Fangzhou "Jo" Bian with her 2025 American Society for Bone and Mineral Research (ASBMR) Young Investigator Award

Fangzhou "Jo" Bian with her 2025 American Society for Bone and Mineral Research (ASBMR) Young Investigator Award

Fangzhou "Jo" Bian with her 2025 American Society for Bone and Mineral Research (ASBMR) Young Investigator Award standing next to her PI and mentor, Dr. Zhaoyang Liu

Fangzhou "Jo" Bian with her 2025 American Society for Bone and Mineral Research (ASBMR) Young Investigator Award standing next to her PI and mentor, Dr. Zhaoyang Liu

Congratulations to Liu lab's Jo Bian on receiving the 2025 ASBMR Young Investigator Award for her abstract, โ€œA Cartilage-Enriched G Protein-Coupled Receptor Maintains Articular Cartilage Homeostasis via Promoting Gs Signaling in Mice,โ€ which she presented at the @asbmr.bsky.social Annual Meeting!

08.09.2025 18:31 ๐Ÿ‘ 3 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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The research that saves lives, sparks innovation and drives change is happening right now. Thanks to Big Ten universities, solutions are being delivered to help communities grow, thrive and overcome challenges.

27.08.2025 17:35 ๐Ÿ‘ 5 ๐Ÿ” 6 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Associate Professor Jianfu Chen welcomes the newest group of Craniofacial Biology (CBY) PhD students at CBY Orientation Day

Associate Professor Jianfu Chen welcomes the newest group of Craniofacial Biology (CBY) PhD students at CBY Orientation Day

On Tuesday, we welcomed our newest Craniofacial Biology (CBY) students with a fun and information Orientation Day! To learn more about our CBY program, check out the CBY website.
dentistry.usc.edu/educational-...

22.08.2025 00:01 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Research Research is fundamental to USCโ€™s mission. It expands human knowledge, cures diseases and saves lives, and serves our community, economy and nation.

"Research is fundamental to USC's mission. Thank you for supporting the faculty who have dedicated their lives to this vital work.โ€ - Interim President Beong Kim #FightOnForResearch weare.sc/rsl-by

17.07.2025 17:00 ๐Ÿ‘ 5 ๐Ÿ” 2 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 1
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Piezo2+ mechanosensory neurons orchestrate postnatal development through mechano-chemo-transduction of PDGFA signaling | PNAS Mechanical forces are ubiquitous and essential during vertebrate development, yet how these forces are translated into biochemical signals and regu...

In the latest paper from Chai lab we reveal the importance of Piezo2+ mechanosensory neurons in postnatal development. Check it out in Proceedings of the National Academy of Sciences (PNAS) @pnas.org. doi.org/10.1073/pnas...

๐Ÿงช #CCMBUSC #Science #USCResearch #CraniofacialBiology

14.07.2025 18:03 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Hello! We are the Center for Craniofacial Molecular Biology of the University of Southern California. May we please be added to the feed? ccmb.usc.edu

08.07.2025 23:31 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
Newly appointed Dean Yang Chai of the Herman Ostrow School of Dentistry of USC

Newly appointed Dean Yang Chai of the Herman Ostrow School of Dentistry of USC

๐ŸŽ‰ Congratulations to Dr. Yang Chai on his appointment as Dean of the Herman Ostrow School of Dentistry of USC, moving from Interim Dean to Dean! Fight on! #CCMBUSC #DentalSchool #USCDentistry #USCResearch #FightOn

04.07.2025 00:37 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Figure 1 from publication depicting scRNA-Seq data on embryonic mouse palate from stages E12.5 through E18.5 and Spatial Genomics data on embryonic mouse head from histological sections from stages E12.5 through E15.5

Figure 1 from publication depicting scRNA-Seq data on embryonic mouse palate from stages E12.5 through E18.5 and Spatial Genomics data on embryonic mouse head from histological sections from stages E12.5 through E15.5

FaceBase has released new datasets from a Nature Communications paper on TGF-ฮฒ Signaling and Craniofacial Morphogenesis with high resolution spatial genomics and scRNA-Seq data!

Learn more here:
www.facebase.org/2025/05/20/r...

20.05.2025 19:42 ๐Ÿ‘ 3 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
We're hiring research lab technicians and postdoctoral scholars

We're hiring research lab technicians and postdoctoral scholars

We're hiring! For more information, visit ccmb.usc.edu/employment-o.... #CCMBUSC #ScienceJobs #CareersinScience #LabLife #MolecularBiology

16.05.2025 00:00 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

OKU is a national honorary society focused on the field of dentistry, founded in 1914 at Northwestern University. Each year, only one faculty member is nominated for this distinction. Weโ€™re proud to celebrate Dr. Moradian-Oldakโ€™s well-deserved honor!

14.05.2025 17:14 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0