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Nicholas Bauer PhD

@bioturbonick.net

Computational biology and superresolution microscopy. Tech and politics nerd. Progressive. Somerville, MA Signal: BioTurboNick.24

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Latest posts by Nicholas Bauer PhD @bioturbonick.net

As an aside, this mindset is often described as "lean" because you skip the "waste" of low fidelity work.

Buddy, no. Low fidelity is not the waste. Work in low fidelity is what prevents the high detail work from being waste. Lean is when cheap-as-free sketches are all you need to avoid that waste.

06.03.2026 16:34 πŸ‘ 58 πŸ” 10 πŸ’¬ 1 πŸ“Œ 0

Vibe coding broke people's brains because they had a bad understanding of the software design process.

The pop culture model goes something like this: start out with a sketch and then render that same idea in progressively finer detail.

So when tools could "skip" to high detail, people went WOW.

06.03.2026 16:19 πŸ‘ 173 πŸ” 40 πŸ’¬ 6 πŸ“Œ 10

When Democrats take back the House, this tool needs to be investigated.

06.03.2026 16:32 πŸ‘ 9 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

LOL. Anthropic may be better than the rest, but they're kooks.

06.03.2026 16:19 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

CBP puts the blame on legacy IT systems. To be blunt, while these problems may be completely valid, this is entirely the fault of the government.

06.03.2026 15:59 πŸ‘ 538 πŸ” 144 πŸ’¬ 47 πŸ“Œ 28

Only 53. Fucking hell.

06.03.2026 16:11 πŸ‘ 7 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
Preview
a cartoon of a man holding a guitar standing next to a computer ALT: a cartoon of a man holding a guitar standing next to a computer

It’s an agent in the same way this thing is an agent

05.03.2026 14:38 πŸ‘ 24 πŸ” 1 πŸ’¬ 4 πŸ“Œ 0

You know how American intelligence was pretty excited to do to the USSR in Afghanistan what Soviet intelligence did to the US in Vietnam?

06.03.2026 14:44 πŸ‘ 369 πŸ” 96 πŸ’¬ 30 πŸ“Œ 5

A military culture where the Secretary say he will ignore β€œstupid rules of engagement” leads to the US sinking what they likely knew was an unarmed ship, killing more than 80 sailors with 62 others still missing.

06.03.2026 13:42 πŸ‘ 413 πŸ” 160 πŸ’¬ 19 πŸ“Œ 10
Post image

This is not good.

06.03.2026 13:40 πŸ‘ 5994 πŸ” 2492 πŸ’¬ 542 πŸ“Œ 362

Update: it was fine. Kind of mild, but fine.

06.03.2026 07:23 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
Exclusive: US investigation points to likely US responsibility in Iran school strike, sources say Military investigators believe it is likely that U.S. forces were responsible for an apparent strike on an Iranian girls' school that killed scores of children on Saturday, two U.S. officials told Reu...

Reuters Exclusive

"U.S. military investigators believe it is likely that U.S. forces were responsible for an apparent strike on an Iranian girls' school."

"The strike would rank among the worst cases of civilian casualties in decades of U.S. conflicts in the ​Middle East."

06.03.2026 02:50 πŸ‘ 9233 πŸ” 4927 πŸ’¬ 572 πŸ“Œ 598

the thing about β€œwe’re not going through the strait of hormuz because we might get hit by missiles” is that even if you do actually take out Iran’s capacity to do that you’ve gotta convince the people actually piloting the ships that it’s safe

and this is not exactly the most trustworthy group

06.03.2026 03:09 πŸ‘ 837 πŸ” 82 πŸ’¬ 17 πŸ“Œ 9
Mia Asano poster with tour dates

Mia Asano poster with tour dates

Just saw Mia Asano's show in Worcester!

Most of her songs are originals, but she also does a few covers, a mix of nerdy and rock.

If she comes around your area, I highly recommend going to see her play! I guarantee you'll have a good time.

06.03.2026 03:02 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Anyway, can someone remind me who the heads of the DHS and FBI are at the moment?

Surely they will stop any such an attack.

06.03.2026 01:07 πŸ‘ 1231 πŸ” 230 πŸ’¬ 64 πŸ“Œ 9

Uhhhhh.... No, sorry, we need to reverse the idea that taxes are bad. It's just a race to the bottom.

06.03.2026 00:23 πŸ‘ 10 πŸ” 0 πŸ’¬ 3 πŸ“Œ 0

Joe Biden earned far more media fury for ending a war than Trump will for starting one.

06.03.2026 00:15 πŸ‘ 304 πŸ” 48 πŸ’¬ 2 πŸ“Œ 2
Amid reports of CIA links to Iranian Kurds, one militia makes a curious purchase
Vasco Cotovio
Clarissa Ward
By Vasco Cotovio, Clarissa Ward and Nechirvan Mando
As tension becomes increasingly palpable in northern Iraq – caught between pressure from the United States and threats from Iran – the owner of a car dealership in the city of Erbil told CNN one Iranian Kurdish militia bought 50 Toyota Land Cruiser LC71 in one go.

CNN agreed not to disclose the name of the group to safeguard the dealer’s identity.

Amid reports of CIA links to Iranian Kurds, one militia makes a curious purchase Vasco Cotovio Clarissa Ward By Vasco Cotovio, Clarissa Ward and Nechirvan Mando As tension becomes increasingly palpable in northern Iraq – caught between pressure from the United States and threats from Iran – the owner of a car dealership in the city of Erbil told CNN one Iranian Kurdish militia bought 50 Toyota Land Cruiser LC71 in one go. CNN agreed not to disclose the name of the group to safeguard the dealer’s identity.

CIA (car intelligence agency)

06.03.2026 00:05 πŸ‘ 74 πŸ” 7 πŸ’¬ 11 πŸ“Œ 5

I would buy one or two to serve as distractions.

06.03.2026 00:09 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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whew

05.03.2026 23:52 πŸ‘ 310 πŸ” 40 πŸ’¬ 27 πŸ“Œ 7
Visual Voicemail showing one message a day all the same length

Visual Voicemail showing one message a day all the same length

All of these are AI voice loan scams.

05.03.2026 23:53 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

if you were to write a prophecy of the future back in 2000 that "in 2026, President Donald John Trump has launched a war on Iran with Israel after previously attempting a coup to stay in power in 2020", people would think you've gone insane

05.03.2026 23:16 πŸ‘ 963 πŸ” 137 πŸ’¬ 27 πŸ“Œ 18
A Reductress post features a photo of Kristi Noem with the headline, β€œKristi Noem Put Down for Being Too Hard to Train”

A Reductress post features a photo of Kristi Noem with the headline, β€œKristi Noem Put Down for Being Too Hard to Train”

Screaming

05.03.2026 22:00 πŸ‘ 15403 πŸ” 3159 πŸ’¬ 233 πŸ“Œ 158

Something about this LLM tech just made everybody forget all the lessons learned over decades about keeping parts of your architecture separate, or being clear about system behavior with human users etc.

05.03.2026 22:08 πŸ‘ 9 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0

There are like 8 different font sizes and weights in there.

05.03.2026 21:46 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Do waves bend?

05.03.2026 21:37 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Using ChatGPT for this is bad even if credited.

05.03.2026 21:36 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
Video thumbnail

WAR CRIME BY THE US.

An unarmed Iranian ship was takIng part in an Indian naval exercise, alongside the US.

The US withdrew and torpedoed the Iranian ship.

THEN the US refused to rescue the sailors, letting them drown.

This is treachery, cowardice, cruelty and a war crime of the highest order.

05.03.2026 19:38 πŸ‘ 1753 πŸ” 981 πŸ’¬ 131 πŸ“Œ 93
Preview
Screw Covid, I'm going to Sturgis. Troy Tassier is a professor of economics at Fordham University and the author of The Rich Flee and the Poor Take the Bus: How Our Unequal Society Fails Us during Outbreaks.

"Screw Covid, I'm going to Sturgis!" The Sturgis Motorcycle Rally, held in August 2020, was the epitome of the individual choice mindset. Of course it spread cases outward and caused infections, illness, and death. A new research paper allows us to watch the Sturgis Covid wave spread across the US.

05.03.2026 15:58 πŸ‘ 275 πŸ” 113 πŸ’¬ 6 πŸ“Œ 12

Maybe drones would let them...

05.03.2026 20:51 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0