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Ryan Senne (he/him)

@ryguy.io

Computational Neuroscience Ph.D. Student @ Boston University. Labs of Dr. Brian DePasquale, Ben Scott, & Steve Ramirez. #JuliaLang stan.

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21.09.2023
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Latest posts by Ryan Senne (he/him) @ryguy.io

Checkout the notebook of this epic neuroscience dataset now on @dandiarchive.org and analyzed with pynapple!

27.02.2026 17:05 πŸ‘ 18 πŸ” 6 πŸ’¬ 0 πŸ“Œ 2
PNAS Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

So happy to announce my first published paper: Neuropixels reveal laminar microcircuit organization in monkey V1 in vivo
www.pnas.org/doi/epdf/10....

18.02.2026 22:20 πŸ‘ 19 πŸ” 5 πŸ’¬ 1 πŸ“Œ 1

I am a pro-AI guy who often gets pigeonholed as an anti-AI guy. I am pro developing and using AI for things AI is good at. I am anti developing and using AI for things that will bring on another AI winter, a mild economic collapse, and make us all look like schmucks in ~5 years.

17.02.2026 03:35 πŸ‘ 54 πŸ” 4 πŸ’¬ 2 πŸ“Œ 0

As a proud Minnesotan, I second this

12.02.2026 15:50 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

nearly a thousand entries

31.01.2026 05:47 πŸ‘ 20 πŸ” 6 πŸ’¬ 5 πŸ“Œ 5

Gary Larson: In my cartoon I invented Cow Tools as a cautionary tale

Cows: At long last, we have created the Cow Tools from classic newspaper comic Cow Tools

19.01.2026 17:04 πŸ‘ 14125 πŸ” 4060 πŸ’¬ 78 πŸ“Œ 34
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Walz: "What's happening in MN defies belief. News reports simply don't do justice to the level of chaos & disruption & trauma the federal govt is raining down... This long ago stopped being a matter of immigration enforcement. Instead, it's a campaign of organized brutality against the people of MN"

15.01.2026 02:17 πŸ‘ 44150 πŸ” 16176 πŸ’¬ 1629 πŸ“Œ 868

I really want ppl w/o Minneapolis connections to understand

You might've heard that Mpls public schools went hybrid bc so many families are in hiding. Well, a coworker just told me that today, during his kid's hybrid class, a kid's apt building was raided onscreen

*Everyone has stories like this*

13.01.2026 18:06 πŸ‘ 19761 πŸ” 8233 πŸ’¬ 355 πŸ“Œ 357
β€œRenee was one of the kindest people I’ve ever known,” she said. β€œShe was extremely compassionate. She’s taken care of people all her life. She was loving, forgiving and affectionate. She was an amazing human being.”

β€œRenee was one of the kindest people I’ve ever known,” she said. β€œShe was extremely compassionate. She’s taken care of people all her life. She was loving, forgiving and affectionate. She was an amazing human being.”

The woman killed by ICE was Renee Nicole Good, a 37-year old who was the mother of a 4-year old child whose father already died a few years ago.

The Star Tribune talked to her mother. www.startribune.com/she-was-an-a...

07.01.2026 22:38 πŸ‘ 7007 πŸ” 2610 πŸ’¬ 162 πŸ“Œ 159

BBC is reporting that the same ICE officer who murdered Renee Good was involved in another violent incident in June.

07.01.2026 23:46 πŸ‘ 7232 πŸ” 2543 πŸ’¬ 270 πŸ“Œ 175
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NOW: Crowd continues to grow in Minneapolis at a vigil where a federal agent shot and killed Renee Good this morning.

β€œSAY HER NAME!”
β€œRENEE GOOD!”

07.01.2026 23:22 πŸ‘ 15124 πŸ” 4777 πŸ’¬ 287 πŸ“Œ 185

If you knew Renee Nicole Good - the 37 year old killed by ICE in Minneapolis today - please text me at 202-510-1268. You can remain anonymous

07.01.2026 23:50 πŸ‘ 562 πŸ” 123 πŸ’¬ 6 πŸ“Œ 2

A meta-analysis of studies using Tolman’s sunburst maze suggests poor replicability and little evidence for shortcutting. Ouch! Definitely relevant reading for anyone interested in cognitive maps! πŸ‘‡

06.01.2026 11:26 πŸ‘ 24 πŸ” 4 πŸ’¬ 1 πŸ“Œ 0

Given the popularity and centrality of neuronal calcium imaging to systems and cellular neuroscience, it is shockingly under-modelled. Makes me nervous about the conclusions from those studies.

At least the fMRI BOLD interpretation gets routinely debated...

05.01.2026 20:07 πŸ‘ 4 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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The serotonin 1B receptor is required for some of the behavioral effects of psilocybin in mice - Molecular Psychiatry Molecular Psychiatry - The serotonin 1B receptor is required for some of the behavioral effects of psilocybin in mice

New paper drop! πŸ§ πŸ’Š Our new paper out in Molecular Psychiatry shows that the serotonin 1B receptor is important for the neural and antidepressant/anxiolytic behavioral responses to psilocybin in mice.

www.nature.com/articles/s41...

21.12.2025 19:50 πŸ‘ 53 πŸ” 17 πŸ’¬ 6 πŸ“Œ 2

The reviewer 2 special I see

22.12.2025 01:57 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Well that’s just absurd…

22.12.2025 01:55 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

🚨 We are recruiting a full-time Research Programmer to push forward several exciting machine learning projects in the lab!

Work on computational behavior and joint neural/behavior models. Start date flexible, can be a pre-grad-school position or longer term.

recruiting2.ultipro.com/SCR1003TSRI/...

10.12.2025 16:40 πŸ‘ 18 πŸ” 12 πŸ’¬ 0 πŸ“Œ 0
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Are manifolds real?
Are latent circuits real?
Tatiana @engeltatiana.bsky.social uses one, infers the other, and says yes to both.

Also, how timescales are different and the same across the entire brain...

braininspired.co/podcast/226/

04.12.2025 18:52 πŸ‘ 38 πŸ” 11 πŸ’¬ 2 πŸ“Œ 1
A close up of the trophy for the "prix science ouverte du logiciel libre de recherche, Γ©dition 2025" (open science prize for free research software, 2025 edition)

A close up of the trophy for the "prix science ouverte du logiciel libre de recherche, Γ©dition 2025" (open science prize for free research software, 2025 edition)

My baby #JuliaLang package got an award!
DifferentiationInterface.jl just received a national prize for open-source research software and I couldn't be prouder. We started this from a vague dream with @adrianhill.de, and reached 1000 dependents and 100k downloads last month.
Research != just papers.

02.12.2025 09:55 πŸ‘ 89 πŸ” 13 πŸ’¬ 10 πŸ“Œ 1

Awesome to see the French government recognize our work on open-source software! @ouvrirlascience.bsky.social

02.12.2025 19:03 πŸ‘ 15 πŸ” 3 πŸ’¬ 1 πŸ“Œ 0

Simulation-based inference has really become a commonly used tool for parameter inference across many fields and applications. We (finally...) got together to write a tutorial introduction and guide to (hopefully) help users get started and navigate the different methods and diagnostics!

21.11.2025 15:34 πŸ‘ 38 πŸ” 11 πŸ’¬ 1 πŸ“Œ 0

Check out cool new work from the DePaq lab!

20.11.2025 16:13 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

W3/W7/W11 too!

15.11.2025 20:44 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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check out the @okaysteve.bsky.social lab’s posters (for both neuron and glia enthusiasts) at #SfN2025 on Saturday PM! especially say hello to @siriacoello.bsky.social who is applying to grad school this cycle✨

14.11.2025 19:10 πŸ‘ 9 πŸ” 5 πŸ’¬ 1 πŸ“Œ 0
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GitHub - depasquale-lab/StateSpaceDynamics.jl: Julia library for fitting and analyzing state space models. Provides efficient implementations of various SSMs including the canonical Gaussian LDS (Kalm... Julia library for fitting and analyzing state space models. Provides efficient implementations of various SSMs including the canonical Gaussian LDS (Kalman Filter/Smoother), Poisson LDS, HMMs, etc....

And also thanks to @zachloschin.bsky.social and fellow bluesky-less authors for making this happen with me! Of course also a huge shout out to the @julialang.org, the friendliest OSS community ever created. Our GitHub: github.com/depasquale-l...

14.11.2025 16:29 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

but Julia has not...until now! This project was incredibly fun and really was a labor of love. Please check us out on GitHub! We are still in active development so the model offerings are only bigger! Special thanks to @briandepasquale.bsky.social for being a phenomenal mentor for this project!

14.11.2025 16:29 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

🚨🚨🚨NEW PAPER ALERT🚨🚨🚨

We present StateSpaceDynamics.jl, an open-source Julia package for fitting probabilistic state-space models (SSMs)β€”including non-conjugate models like Poisson LDS and switching variants (SLDS). Python has had existing packages that have given this functionality...

14.11.2025 16:29 πŸ‘ 9 πŸ” 4 πŸ’¬ 1 πŸ“Œ 1
Event flyer for β€˜The Language of Light: Bioluminescence in the Deep Sea.’ Details: Friday, Nov 14, 4:00 to 5:30 pm, Benson Earth Sciences Auditorium, Room 180. Speaker: SΓΆnke Johnsen, Owens Distinguished Professor, Duke University. Reception 5:30 to 6:30 pm at the Earth Sciences & Map Library. Free, open to the public

Event flyer for β€˜The Language of Light: Bioluminescence in the Deep Sea.’ Details: Friday, Nov 14, 4:00 to 5:30 pm, Benson Earth Sciences Auditorium, Room 180. Speaker: SΓΆnke Johnsen, Owens Distinguished Professor, Duke University. Reception 5:30 to 6:30 pm at the Earth Sciences & Map Library. Free, open to the public

Boulder friends: if you’re into animal behavior or vision, come to The Language of Light: Bioluminescence in the Deep Sea with SΓΆnke Johnsen (Duke)!

Fri Nov 14, 4-5:30 pm, Benson Earth Sciences Auditorium, Room 180. Reception 5:30-6:30 at the Earth Sciences & Map Library

Free and open to all!

09.11.2025 20:54 πŸ‘ 11 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

Great gerbil content Estelle!

31.10.2025 17:23 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0