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PRESS RELEASE
Fennec Pharmaceuticals 
Announces Clinical Research 
Collaboration with Tampa General Hospital Cancer Institute

PRESS RELEASE Fennec Pharmaceuticals Announces Clinical Research Collaboration with Tampa General Hospital Cancer Institute

We’re pleased to announce that the Tampa General Hospital Cancer Institute is initiating a study to evaluate real-world utility of PEDMARK® (sodium thiosulfate injection).
Learn more: bit.ly/3PfBj4N

#Ototoxicity #ChemoSideEffects #PatientOutcomes #ClinicalResearch #HearingHealth #CancerCare

1 week ago 0 0 0 0

Hearing connects us — to learning, to independence, to each other.
Acting early matters.
Monitoring matters.
Prevention matters.

This #WorldHearingDay, let’s ensure no young person is left behind.

1 week ago 0 0 0 0

Cisplatin-induced hearing loss can:
• Be permanent
• Progress over time
• Impact speech & language development
• Affect academic & social outcomes

And for young adults, it can shape education, career paths and quality of life.

1 week ago 0 0 1 0
FENNEC PHARMA
March 3 marks #WorldHearingDay

FENNEC PHARMA March 3 marks #WorldHearingDay

March 3 is #WorldHearingDay.
This year, @who.int calls us to act now so no child is left behind due to hearing loss.
For children and young adults treated with cisplatin, hearing loss is not a rare side effect — it’s a lifelong consequence.
🧵👇

1 week ago 0 0 1 0
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Behind every person diagnosed with cancer is a network of caregivers: family members, friends & professionals, who provide essential support each day. On #NationalCaregiversDay, and every day, we recognize the critical role caregivers play in the lives of those navigating cancer.

3 weeks ago 0 0 0 0
PRESS RELEASE

Fennec Pharmaceuticals Presents Real World Data Supporting the Integration and Clinical Use of PEDMARK in Treating Adults with Head and Neck Cancers

PRESS RELEASE Fennec Pharmaceuticals Presents Real World Data Supporting the Integration and Clinical Use of PEDMARK in Treating Adults with Head and Neck Cancers

We were pleased to present new real-world data in adults with head and neck cancers at the 2026 Multidisciplinary Head and Neck Cancers Symposium.

Read more: investors.fennecpharma.com/news-release...

#CisplatinInducedOtotoxicity #ChemoSideEffects #ClinicalResearch #MHNC26

3 weeks ago 1 0 0 0

At the same time, some survivors face lasting effects, such as irreversible hearing loss, which can impact learning, communication & daily life. Today is a moment to honor resilience, acknowledge long-term challenges and continue working toward better outcomes for every child.

3 weeks ago 0 0 0 0
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On #InternationalChildhoodCancerDay, we recognize children & families whose lives are changed by a cancer diagnosis, and the long journey after treatment ends. Advances in therapy, including cisplatin-based chemotherapy, have improved survival for many childhood & #AYA cancers.

3 weeks ago 0 0 1 0
Why is hearing health often overlooked?

Tinnitus Awareness Week
February 2-8
Image of a gold and silver ribbon

Why is hearing health often overlooked? Tinnitus Awareness Week February 2-8 Image of a gold and silver ribbon

Tinnitus - the perception of noise or ringing in the ears - may be the 1st sign of #CisplatinInducedOtotoxicity (CIO) in some cancer patients undergoing #chemotherapy. Risks of CIO are higher for children & #AYA and the effects can be irreversible.

#TinnitusAwarenessWeek

1 month ago 0 0 0 0
Image shows words: DESPAIR - LOSS - GRATITUDE - SADNESS - TRUST - CONFUSION - GRIEF - CANCER - LONELINESS - PEACE - COMPASSION - SADNESS - HOPE - STRENGTH - RESILIENCE - PAIN - DOUBT - LOVE - RELIEF - CONNECTION - ANGER - SHOCK - ENDURANCE

United in our Triumphs
Unique in our Challenges

Share Your Story
WorldCancerDay.org
World Cancer Day 
4 February
United By Unique

Image shows words: DESPAIR - LOSS - GRATITUDE - SADNESS - TRUST - CONFUSION - GRIEF - CANCER - LONELINESS - PEACE - COMPASSION - SADNESS - HOPE - STRENGTH - RESILIENCE - PAIN - DOUBT - LOVE - RELIEF - CONNECTION - ANGER - SHOCK - ENDURANCE United in our Triumphs Unique in our Challenges Share Your Story WorldCancerDay.org World Cancer Day 4 February United By Unique

Behind every cancer diagnosis is a unique human story of grief, pain, hope, healing, & resilience. People-centered care means seeing the whole person and meeting their needs through comprehensive care teams to manage treatment-related side effects.

#WorldCancerDay #UnitedByUnique

1 month ago 2 0 1 0
The 5-year survival rate for all cancers combined is now approximately 69% due to major treatment advances such as platinum-based chemotherapy like cisplatin. 

However, an unfortunate side effect of cisplatin treatment is irreversible ototoxicity, or hearing loss.

The 5-year survival rate for all cancers combined is now approximately 69% due to major treatment advances such as platinum-based chemotherapy like cisplatin. However, an unfortunate side effect of cisplatin treatment is irreversible ototoxicity, or hearing loss.

With overall survival rates of all #cancers better than in previous decades, managing side effects of treatment - such as hearing loss from platinum-based #chemotherapy - is more important than ever.

Learn more about this common side effect:
fennecpharma.com/science/cispla

#Ototoxicity

1 month ago 0 0 0 0
Image of teal and white ribbons for cervical cancer and 4 icons illustrating communication 
Cervical Cancer Summit 
Powered by Cervivor
January 23, 2026

Image of teal and white ribbons for cervical cancer and 4 icons illustrating communication Cervical Cancer Summit Powered by Cervivor January 23, 2026

We’re looking forward to joining experts, patients, survivors, and advocates at the #CervicalCancer Summit powered by #Cervivor in Washington DC this week.

#CervicalCancerAwarenessMonth @cervivor.bsky.social

1 month ago 0 0 0 0
Photo of Martin Luther King Jr.
"If you can't fly then run, 
if you can't run than walk, 
if you can't walk then crawl, 
but whatever you you do 
you have to keep moving forward."

Photo of Martin Luther King Jr. "If you can't fly then run, if you can't run than walk, if you can't walk then crawl, but whatever you you do you have to keep moving forward."

Today we honor the life of Dr. Martin Luther King, Jr., and his legacy of strength, compassion, and courage. #MLKDay #MLK

1 month ago 1 0 0 0
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Our mission is to help protect hearing for children, adolescents and young adults undergoing treatment for cancer with cisplatin-based chemotherapy, so they can look forward to a future filled with possibility.

#HearingHealth #Ototoxicity #ChemoSideEffects

1 month ago 1 0 0 0
January 12
National Pharmacists Day

January 12 National Pharmacists Day

Pharmacists are more than medication experts—they’re trusted advocates & integral members of patient care teams. From administering treatments to managing chronic conditions, pharmacists directly impact patient care.

On #NationalPharmacistsDay, we thank them for all they do!

2 months ago 2 0 0 0
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2025 was a year of building, believing, and delivering.

From advancing science & expanding access, to showing up for patients and families who inspire everything we do, 2025 proved what’s possible when purpose and performance go hand in hand. And we’re just getting started.

2 months ago 2 0 0 0
Cervical Cancer Awareness Month
January

Cervical Cancer Awareness Month January

During #CervicalCancerAwarenessMonth, we stand with patients, survivors, and families. Cervical cancer is preventable and treatable when caught early.

With higher survival, quality of life matters—advocate for hearing loss monitoring and prevention.

2 months ago 2 0 0 0
"Every moment is a new beginning."
-Elie Wiesel

"Every moment is a new beginning." -Elie Wiesel

The Fennec team wishes everyone a Happy, Healthy & Bright New Year!

2 months ago 1 0 0 0
Graphic with 'Happy Holidays! surrounding with holiday imagery including ornaments, gift boxes, bows, candles, snowflakes, leaves, flowers, stars and cakes

Graphic with 'Happy Holidays! surrounding with holiday imagery including ornaments, gift boxes, bows, candles, snowflakes, leaves, flowers, stars and cakes

Happy Holidays from all of us at Fennec!

We wish our colleagues, partners and the people we serve a joy-filled and safe holiday season.

2 months ago 1 0 0 0
"It just happened, and I had no idea. 
I would've, at the very least, like to know, like hey, you might lose your hearing. 

Having it told to me would definitely have been helpful. Like even just mentally preparing myself for something that might happen."

-Jake
Cancer survivor with cisplatin-induced hearing loss

"It just happened, and I had no idea. I would've, at the very least, like to know, like hey, you might lose your hearing. Having it told to me would definitely have been helpful. Like even just mentally preparing myself for something that might happen." -Jake Cancer survivor with cisplatin-induced hearing loss

Cisplatin-based chemotherapy is an effective treatment for #cancer, but some patients and survivors are left with permanent hearing loss, or #ototoxicity, that impacts their quality of life long after treatment ends.

#SoundsOfTheSeason #HearingHealth #ChemoSideEffects

2 months ago 1 0 0 0

With the holidays approaching, people will soon gather with friends, family, co-workers & even strangers in festivities large & small. There will be music & singing, laughter & conversation, glasses clinking & bells ringing. But not everyone will be able to hear these sounds. 🗣️ 🎄 🎶 🥂

2 months ago 0 0 1 0
Image of a woman fitting headphones on a child.

Text:
Audiologists are essential in oncology care
Before treatment 
-Establish a baseline record of hearing and balance
During treatment 
-Administer periodic hearing tests to monitor for any changes, ringing in ears (tinnitus), or balance problems
-Communicate with oncology team and suggest treatment options
After treatment
-Continue to monitor and evaluate

Image of a woman fitting headphones on a child. Text: Audiologists are essential in oncology care Before treatment -Establish a baseline record of hearing and balance During treatment -Administer periodic hearing tests to monitor for any changes, ringing in ears (tinnitus), or balance problems -Communicate with oncology team and suggest treatment options After treatment -Continue to monitor and evaluate

Not being able to fully hear or feeling dizzy can make daily activities challenging. 60 - 90% of #cancer patients develop #ototoxicity from cisplatin-based chemotherapy. Audiological monitoring is an essential component of #oncology care.

#HearingHealth #ComprehensiveCare

3 months ago 2 0 0 0
PRESS RELEASE
Fennec Pharmaceuticals
Announces Investigator-Sponsored Trial to be Conducted by City of Hope in Metastatic Testicular Germ Cell Tumors

PRESS RELEASE Fennec Pharmaceuticals Announces Investigator-Sponsored Trial to be Conducted by City of Hope in Metastatic Testicular Germ Cell Tumors

Today we announced the planned initiation of an IST at @cityofhope.bsky.social to evaluate PEDMARK® (sodium thiosulfate injection) for preventing cisplatin-induced #ototoxicity (CIO) in adult men with stage II-III metastatic testicular germ cell tumors. bit.ly/3KvDPCd #CancerCare #ClinicalResearch

3 months ago 2 0 0 0
Preview
PEDMARK® Study in Japan Shows Significant Reduction in Cisplatin-Related Hearing Loss in Pediatric Patients | Hearing Health & Technology Matters RESEARCH TRIANGLE PARK, N.C. — Fennec Pharmaceuticals Inc. (NASDAQ: FENC; TSX: FRX), a specialty pharmaceutical company, today announced positive topline results from the investigator-initiated Phase ...

“These encouraging results from the first large-scale pediatric and adolescent and young adults (AYA) trial in Japan demonstrate that PEDMARK® can protect hearing without compromising cisplatin’s efficacy or introducing any concerning side effects.” hearinghealthmatters.org/hearing-news... #cancer

3 months ago 1 1 0 0
International Day of Persons with Disabilities
December 3

International Day of Persons with Disabilities December 3

On #InternationalDayofPersonsWithDisabilities, we honor the strength and resilience of individuals with disabilities.

Promoting their rights and well-being is essential for creating a kinder, more supportive and inclusive society.

#DisabilityRights

3 months ago 2 0 0 0
PRESS RELEASE
Fennec Pharmaceuticals 
Announces Positive Topline Results from Investigator-Initiated Clinical Study of PEDMARK in Japan to Reduce Cisplatin-Induced Hearing Loss

PRESS RELEASE Fennec Pharmaceuticals Announces Positive Topline Results from Investigator-Initiated Clinical Study of PEDMARK in Japan to Reduce Cisplatin-Induced Hearing Loss

We announced positive topline results from the investigator-initiated Phase 2/3 STS-J01 clinical trial of PEDMARK® (sodium thiosulfate injection) for the reduction of cisplatin-induced #ototoxicity in pediatric & #AYA patients w/ solid tumors in Japan. Read investors.fennecpharma.com/news-release...

3 months ago 1 0 0 0
Image with leaves and acorns

Appreciation can make a day, even change a life. 
Your willingness to put it into words is all that is necessary. 
-Margaret Cousins

Image with leaves and acorns Appreciation can make a day, even change a life. Your willingness to put it into words is all that is necessary. -Margaret Cousins

Thank you to our wonderful team for all your hard work, dedication, and passion. It is the people that make Fennec so special. We wish you a Happy Thanksgiving with family, friends, and loved ones.

#Thanksgiving #Gratitude

3 months ago 3 0 0 0
Graphic titled: Oncology teams work together to provide care before, during, and after treatment.

Graphic has four circles: 
Center image of child with otoscope being held close to his ear
Top right image is a woman viewing an x-ray
Bottom right image shows two HCPs
Left image shows an occupational therapist with a child

Graphic titled: Oncology teams work together to provide care before, during, and after treatment. Graphic has four circles: Center image of child with otoscope being held close to his ear Top right image is a woman viewing an x-ray Bottom right image shows two HCPs Left image shows an occupational therapist with a child

Cisplatin is a cornerstone #chemotherapy but comes w/ a high risk of #ototoxicity. Children are more susceptible to the permanent hearing loss, but it impacts QoL for all patients -including #AYA.

Audiologists monitor for early signs & educate patients & HCPs on #hearing health.

#CancerCare

3 months ago 3 0 0 0
Image of people with arms around each other's shoulders

THANK YOU Caregivers

Image of people with arms around each other's shoulders THANK YOU Caregivers

Living with childhood and #AYA #cancer takes bravery and resilience. Not only from patients but also from the many caregivers who support them every day. We are grateful for their strength, unwavering dedication, and compassion.

#FamilyCaregiversMonth

3 months ago 1 0 0 0
Oto-tox-icity
Noun
OTOTOXICITY refers to inner ear damage from exposure to certain drugs of chemicals, leading to hearing loss, tinnitus, and balance issues.

Oto-tox-icity Noun OTOTOXICITY refers to inner ear damage from exposure to certain drugs of chemicals, leading to hearing loss, tinnitus, and balance issues.

Platinum-based drugs, including cisplatin, are effective treatments for #cancer, but they may cause permanent hearing damage known as #ototoxicity.

To minimize the risk of long-term effects, auditory monitoring & assessments can help improve patient outcomes.

#ChemoSideEffects #ComprehensiveCare

3 months ago 4 1 0 0
Fennec Pharmaceuticals
Fennec Pharmaceuticals
@fennecpharma.com
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