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Bill Katz

@billkatz.com

Programmer/scientist at HHMI Janelia Research Campus. Research interests include AI/ML, datastores, viz for imaging and sparse volumes. Consumer and very infrequent producer of fiction.

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07.02.2024
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Latest posts by Bill Katz @billkatz.com

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Excited to share our new #biorxivpreprint:
“Sexual dimorphism in the complete connectome of the Drosophila male central nervous system” www.biorxiv.org/content/10.1...

We describe the #connectomics reconstruction and analysis of an entire adult #maleCNS #drosophila central nervous system. 1/10

15.10.2025 16:17 👍 123 🔁 67 💬 1 📌 5

The male CNS is out with a number of papers to follow!

06.10.2025 14:30 👍 2 🔁 0 💬 0 📌 0
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Connectome-driven neural inventory of a complete visual system - Nature A connectome of the right optic lobe from a male fruitfly is presented together with an extensive collection of genetic drivers matched to a comprehensive neuron-type catalogue.

I know there's a 𝒍𝒐𝒕 going on right now, but I couldn’t be prouder to share this long-incubated labor of love: the complete connectome of the male 𝐷𝑟𝑜𝑠𝑜𝑝ℎ𝑖𝑙𝑎 optic lobe 🧠🪰
🔗 www.nature.com/articles/s41...

27.03.2025 22:58 👍 217 🔁 78 💬 12 📌 4
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TensorStore (github.com/google/tensorstore) has had a huge 2024 and continues to power checkpointing for much of the largest ML work at Google, including Gemini, and support major Google Cloud customers training models on GCP. Read on for some specific 2024 updates!

18.12.2024 16:54 👍 10 🔁 2 💬 1 📌 0
The Amazing Working Style of Germans

The Amazing Working Style of Germans

25.11.2024 05:08 👍 1 🔁 0 💬 0 📌 0
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We are looking for a Scientific Computing Associate to develop AI/ML methods to identify the ancestors of genes of unknown origin, an exciting project with the Stern lab @ HHMI Janelia.

We are looking someone with AI/ML experience.

hhmi.wd1.myworkdayjobs.com/en-US/Extern...

@hhmi.bsky.social

24.11.2024 23:37 👍 5 🔁 6 💬 0 📌 0

I love audiobooks and because of them, I've found the time to enjoy more wonderful short stories and novels. We should also distinguish audiobooks of dramatic adaptations vs narration of unabridged works. For me, the latter is just a format change.

23.11.2024 18:15 👍 0 🔁 0 💬 0 📌 0
Sci Viz 2022-05-12: Advanced Rendering Methods for Scientific Insight (John Stone)
Sci Viz 2022-05-12: Advanced Rendering Methods for Scientific Insight (John Stone) YouTube video by Scientific Computing Software (HHMI Janelia)

John E. Stone made a similar point about shape perception in his talk for the Janelia Scientific Visualization Interest Group (organized by @wthang.bsky.social), although he uses ambient occlusion instead of path tracing for performance reasons.
www.youtube.com/watch?v=Vzx0...

16.11.2024 10:26 👍 2 🔁 1 💬 0 📌 0
Neurons from the Drosophila SMP region, first with shadows from global illumination, then without.

Neurons from the Drosophila SMP region, first with shadows from global illumination, then without.

I like to use #GlobalIllumination ( #PathTracing ) for #SciVis ( #SciViz ) because it creates the cues our visual systems use to perceive 3D shapes. For example, without shadows it is almost impossible to see the bulge in the middle of these SMP neurons from #Drosophila #Neuroscience data.

15.11.2024 13:09 👍 22 🔁 4 💬 1 📌 0
AI@HHMI teaser saying "AI@HHMI | Accelerating Innovation in Biology". The backdrop is an artistic rendering of the compute graph of a network architecture for semantic image segmentation that I think looks really cute.

AI@HHMI teaser saying "AI@HHMI | Accelerating Innovation in Biology". The backdrop is an artistic rendering of the compute graph of a network architecture for semantic image segmentation that I think looks really cute.

We are looking for exceptional #AIScientist|s to join our #AI@HHMI initiative at #HHMIJanelia. We want to uncover fundamental principles underlying complex biological systems that are inaccessible without new innovations that combine #AI with experimental design.

ai.hhmi.org#join-our-team

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15.11.2024 14:13 👍 53 🔁 33 💬 1 📌 1
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FlyWire #Neuroscience data (green) is now in neuronbridge.janelia.org for matching against #Drosophila light #microscopy data (magenta). Thanks to Cristian Goina, Hideo Otsuna, Rob Svirskas, Konrad Rokicki. See a match in the browser, using mixed surface / volume rendering implemented with #threejs.

23.11.2024 10:27 👍 33 🔁 12 💬 1 📌 1
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Did you know a fruit fly’s brain has its own internal compass? Studying these neurons helps scientists explore how brains process spatial information, offering insights into navigation across species.

This image is from HHMI’s Beautiful Biology initiative.

⬇️ ℹ️: www.hhmi.org/beautifulbio...

19.11.2024 20:21 👍 22 🔁 3 💬 0 📌 2

We couldn't do the Connectomics research we do without the advances in deep learning over the last decade. Blockchains aren't just databases, they're distributed ones with observable provenance.

23.02.2024 18:07 👍 0 🔁 0 💬 0 📌 0

I've seen the most absurd arguments and stupidity from anti-vaxxers. A favorite is that Long COVID only appears in those who get the jab. When I point out that medical papers describing Long COVID were published well before mRNA vaccines were available, they either say I'm lying or ignore that fact.

23.02.2024 17:50 👍 0 🔁 0 💬 0 📌 0

Later research shows measles can cause an immune system reset, leaving victims more susceptible to later infections. Anti-vaxxers championing "natural immunity" and "hygiene hypothesis" issues due to isolation predictably ignore the erasing of a lot of those supposed gains.
asm.org/articles/201...

23.02.2024 17:40 👍 7 🔁 3 💬 1 📌 0

Early in his polemic he writes: "This is all on top of an $83.3 million fine Trump must pay for allegedly defaming the writer E. Jean Carroll."

Allegedly defaming? After a jury's verdict isn't there a better adverb? He could have added "after allegedly sexually assaulting..."

20.02.2024 03:38 👍 4 🔁 0 💬 0 📌 0