Kate Beckham

Figure 1. Cryo-EM of abundant protein complexes in native membranes.

Figure 2. Cryo-EM of membrane proteins in vesicles.

Figure 3. 3D reconstruction of V-ATPase in native synaptic vesicle membranes.

Figure 4. Generation of membrane vesicles for structure determination of proteins in their native lipid bilayer.

I've written a review on what I think is an extremely exciting direction in cryo-EM:

Cryo-EM of endogenous membrane proteins in their native lipid bilayer

Open access in Quarterly Reviews of Biophysics:
doi.org/10.1017/S003...

Great talk from @hobbslabmicro.bsky.social - thank you for visiting @mhd-newcastle.bsky.social and telling us why antibiotic tolerance is so important

📢 Last call for the EMBL International PhD Programme summer recruitment!

This is a fully funded PhD programme fostering creative approaches to questions in the molecular life sciences.

Join us promoting scientific excellence throughout Europe. Apply now! www.embl.org/about/info/e...

Biological Laboratory | LEGO® Ideas This is a two-floor realistic Biological Laboratory building. In this design, I try to tell stories about biologists, introduce biology concepts to general publ…

I just made an account and voted for this biology laboratory made of LEGO to "promote biological research and inspire more people into the world of biology". They need 10K votes. Reposting and/or voting below would be helpful. 🤗
beta.ideas.lego.com/product-idea...

Come work with us in Oxford!

www.jobs.ac.uk/job/DQL601/p...

Still 2 weeks left to apply for this position.

Hi. You can send me an email :) my address should be on the uni website.

Sign up now for the EMBO Workshop "The complexity of mycobacterial infections: From research to real-world impact" in #Paris, FR, 14–18 Sep 2026.

Registration by 25 Aug
Abstract submission by 15 May

https://meetings.embo.org/event/26-mycobacterial-infections
#EMBOComplexInfections #EMBOevents 🧪

The building blocks of one of the most complex flagellar nanomachines Nature Microbiology, Published online: 03 February 2026; doi:10.1038/s41564-026-02275-wA near-complete model for the complex structure of the Campylobacter jejuni flagellar motor revealed different mechanisms of assembly, activation and stability from the simple ‘classical’ flagellar model. Some of the additional motor structures in C. jejuni are conserved and only found in species of Campylobacterota, whose ancestor likely co-opted type IV pilus components from bacteria in the deep ocean.

Out Now! The building blocks of one of the most complex flagellar nanomachines #MicroSky

The effect of stress on pollinator behaviour at Newcastle University on FindAPhD.com PhD Project - The effect of stress on pollinator behaviour at Newcastle University, listed on FindAPhD.com

New PhD alert! We'll be applying animal welfare ideas to look at how stress affects bees, looking at the effect on bee brains with @lenariab.bsky.social, and working with @sensibee.bsky.social developing new monitoring methods.

Please spread the word! #bees #PhD 🧪

www.findaphd.com/phds/project...

Cartoon representing the mycobacterial oxidative phosphorylation system, including cytochromes, NDH-2, and ATP synthase. Taken from Figure 1 of the article.

#Microbiology

The anti-tuberculosis drug bedaquiline targets the mycobacterial ATP synthase, but how that leads to bacterial death is unclear

Here the authors clarify how bedaquiline works

@jnblab.bsky.social @morwan.me
#TBSky #antibiotics #AMR

http://dlvr.it/TQjZ0W

Bacteriocin biophysics: From protein-protein interaction models to navigators of the bacterial cell envelope Bacteriocins are toxins deployed by bacteria to kill their competitors. Here, I reflect on my laboratory’s work on protein bacteriocins and their immunity proteins from Gram-negative bacteria. We unco...

A gift of an article from the inimitable Colin Kleanthous as he says a moving farewell to his laboratory. A brave, unrepentant and scientifically brilliant journey is described - please have a read, friends.

www.jbc.org/article/S002...

This is very bad news

Still time to apply for the open postdoc position in our lab!

Very happy that our work on the T6SS ADP-ribosylcyclase toxin made the Cover at JBC @asbmb.bsky.social y.social ! Congratulations Julius @jmartinkus.bsky.social for designing this Cover !
@dukasju.bsky.social @laurentterradot.bsky.social

Forged by Iron: Synthetic protein binders to decode bacterial iron transport mechanisms at Newcastle University on FindAPhD.com PhD Project - Forged by Iron: Synthetic protein binders to decode bacterial iron transport mechanisms at Newcastle University, listed on FindAPhD.com

Fully funded four-year PhD position available in my lab!
Combining structural and synthetic biology to understand iron transport.
Deadline 27th of Feb, get in touch for more details!

www.findaphd.com/phds/project...

Oh yes, very interesting :) thanks Zam

How about a mysterious metal importer in Mycobacterium? Main supervisors @kshbeckham.bsky.social and @mycobacterium-ncl.bsky.social at Newcastle.

www.findaphd.com/phds/project...

Nutrient uptake in commensal bacteria: exploring uncharacterised TonB-dependent transporters. at Newcastle University on FindAPhD.com PhD Project - Nutrient uptake in commensal bacteria: exploring uncharacterised TonB-dependent transporters. at Newcastle University, listed on FindAPhD.com

Lots of PhD opportunities for UK + international students involving my lab. Topics relate to metals & microbiology.

First up: TonB-dependent receptors in commensal Neisseria in my lab at Durham, with @kjosts.bsky.social and @mattbashton.bsky.social.

www.findaphd.com/phds/project...

Microbial metal-head: the integrated roles of metal homeostasis in host-pathogen interaction at Newcastle University on FindAPhD.com PhD Project - Microbial metal-head: the integrated roles of metal homeostasis in host-pathogen interaction at Newcastle University, listed on FindAPhD.com

PhD position available in our team to study how UPEC exploits metals to successfully colonise the host gut. Cool collaboration with @thecopperdoctor.bsky.social and @banzhaflab.bsky.social Please share and get in touch for more details

Characterising antibacterial toxins in the food-borne pathogen Listeria monocytogenes at Newcastle University on FindAPhD.com PhD Project - Characterising antibacterial toxins in the food-borne pathogen Listeria monocytogenes at Newcastle University, listed on FindAPhD.com

www.findaphd.com/phds/project... interested in bacterial antagonism? PhD opportunity in our team, see below. Please repost!

BBSSRC (NEEDL) funded PhD studentship in my lab co-supervised by
@thecopperdoctor.bsky.social and @mycobacterium-ncl.bsky.social
If you're interested in structural biology and membrane transport processes, check out www.findaphd.com/phds/project... deadline 27th of Feb!
Get in touch for more info

Our latest CRISPR ring nuclease paper focusses on Csx15 - which seems to act as of a sponge as well as a canonical phosphodiesterase. Great work led by @haotianchi.bsky.social

www.biorxiv.org/content/10.6...

THE NEXT INSTALLMENT OF BIOLOGY OF MYOCBACTERIA GRC WILL BE IN 2028, NOT 2027. Exact date and location TBD. Sorry about the long wait, but we think it is better long term. PLEASE repost/tell your friends!

How bacterial Tc toxins work: secretion, pore formation and host cell disruption. YouTube video by Max Planck Institute of Molecular Physiology

Our new movie is online, highlighting the assembly, secretion and mechanism of action of bacterial Tc toxins. We hope you enjoy it and use it for teaching purposes or just for fun. Nature is fascinating!

www.youtube.com/watch?v=UfEf...

Structural elucidation of the hexameric MmpS4-MmpL4 complex from Mycobacterium tuberculosis www.biorxiv.org/content/10.64898/2026.01.07.698164v1 #cryoEM

Are you working on challenging projects in structural biology?

#EMBOMacromolecular will highlight the strategic use of cutting-edge protein structure prediction methods, and recent advances in in situ structural biology. Apply by 18 Feb to join us at EMBL Grenoble! 🧬

s.embl.org/mmo26-01-bl

Summer students Our nine-week summer training programme provides undergraduates with hands-on experience of working in a research lab.

Applications to our 2026 Summer Student Training Programme are now open.

We’re looking for undergrad students to join us for nine weeks this summer.

See the projects on offer and check the participation eligibility requirements on our website. ⬇️
www.crick.ac.uk/careers-and-...

🛎️🛎️ Looking for a postdoctoral fellowship? Interested in tackling real-world challenges?

Then check out EMBL's EIPOD-LinC fellowships. Gain transferable skills and work on self-designed projects to make a lasting impact on global issues.

📆 Closing date: 2 February

www.embl.org/about/info/p...

🚨Last chance to apply for two PhD projects in my lab, applying structural biology and single molecule biophysics to investigate gene expression in RNA viruses: www.findaphd.com/phds/?Keywor...