Joshua Shapiro's Avatar

Joshua Shapiro

@josh.shapiro.foo

not ‘Eureka’ but ‘That’s funny…’ Current projects: Biological data and Childhood cancer at http://ccdatalab.org, part of https://alexslemonade.org Not governor.

2,821
Followers
537
Following
317
Posts
27.04.2023
Joined
Posts Following

Latest posts by Joshua Shapiro @josh.shapiro.foo

a headshot of David Botstein

a headshot of David Botstein

We are deeply saddened to share the news of the passing of David Botstein, a towering figure in modern #genetics and a foundational force behind SGD.
www.yeastgenome.org/blog/in-memo... #yeast #modelOrganism

02.03.2026 15:39 👍 52 🔁 29 💬 0 📌 2

I’d put it closer to 0/10.

02.03.2026 01:55 👍 1 🔁 0 💬 0 📌 0

I worked in the adjacent lab when I was postdoc at Princeton, and David Botstein’s influence could not be overstated. I never had a conversation with him where I didn’t learn something. He’ll be missed to be sure.

01.03.2026 23:47 👍 7 🔁 0 💬 0 📌 0
Preview
David Botstein | 1942 - 2026 | Online-Tribute.com David was a beloved husband, father, brother, scientist, teacher, mentor, musician, friend, who touched the lives of thousands. David’s wide-ranging scientific career spanned decades with a legacy o…

Crap

www.online-tribute.com/DavidBotstein

David Botstein passed away. I worked with him at Stanford for a few years in designing and teaching a course on "The Heart". My heart is heavy right now. He was a wonderful mentor.

28.02.2026 22:35 👍 106 🔁 17 💬 5 📌 6

I’m honestly kind of shocked that the word was used in the paper.

27.02.2026 11:36 👍 0 🔁 0 💬 0 📌 0

I know you’re joking, but that is absolutely the worst interpretation of the data. There is absolutely nothing about preference there. Bias in direction of interbreeding, sure, but preferences far from the only explanation for that, let alone the first we should go to.

27.02.2026 11:26 👍 1 🔁 0 💬 1 📌 0
Preview
AIs can’t stop recommending nuclear strikes in war game simulations Leading AIs from OpenAI, Anthropic and Google opted to use nuclear weapons in simulated war games in 95 per cent of cases

Still haven't gotten the AIs to learn that the only winning move is not to play. www.newscientist.com/article/2516...

25.02.2026 16:46 👍 1 🔁 0 💬 0 📌 0

It was a good day to shovel snow and make chili.

24.02.2026 00:41 👍 5 🔁 0 💬 0 📌 0

Is Good Luck, Have Fun, Don’t Die a great movie? Not really. Was it fun? Yes. Did it have maximum Rockwell? Absolutely, and that was all I was asking for.

16.02.2026 00:15 👍 0 🔁 0 💬 0 📌 0

My favorite part was showing it to my high school sophomore, who had just read TKaM and therefore thought it was ridiculous that nobody knew the answer.

14.02.2026 14:11 👍 2 🔁 0 💬 0 📌 0

I am seeking a postdoc to join my group at UCLA -- ideally the candidate would have some experience in either population genetics or microbes/microbiome (computational background needed). We have a range of projects and are happy to tailer to your interests. Please dm/email me if interested.

12.02.2026 19:18 👍 53 🔁 95 💬 0 📌 0
Preview
FDA declines to review Moderna's mRNA flu shot Under Health Secretary Robert F. Kennedy Jr., the Food and Drug Administration has taken an aggressive stance against mRNA technology.

I genuinely cannot believe the degree to which we are pissing away this generational breakthrough, even given the fuckmuppets who are involved www.nbcnews.com/health/healt...

10.02.2026 23:32 👍 8842 🔁 2742 💬 48 📌 243
Preview
Ferrari Luce - Ferrari.com A first look at the interior and interface of the Ferrari Luce. Every element meticulously designed and engineered to be functional, intuitive, and thrilling to drive.

Not gonna lie, I am kind of sad we won’t get an Apple car, because no way I’ll be able to justify a Ferrari. www.ferrari.com/en-EN/auto/f...

10.02.2026 12:39 👍 0 🔁 0 💬 0 📌 0

Bayes Rule in a Super Bowl ad: ✅

09.02.2026 00:05 👍 3 🔁 2 💬 0 📌 0

Did you get apizza?

05.02.2026 23:56 👍 0 🔁 0 💬 1 📌 0
Preview
Introducing Total Crap, the First Magazine Written Entirely by AI Amid doomsaying pronouncements that the publishing industry is dead, we are proud to bring the written word into the future with revolutionary tech...

"Investors must act fast; this is the most exciting get-rich-quick opportunity since Bitcoin started accepting Bitcoin in transactions for Bitcoin."

05.02.2026 02:00 👍 163 🔁 34 💬 3 📌 1

Oh, I meant the country.

05.02.2026 01:22 👍 1 🔁 0 💬 1 📌 0

How optimistic you are!

05.02.2026 01:06 👍 1 🔁 0 💬 1 📌 0

Check out the very important topic:
how does poverty influence childhood cancer biology and treatment response?

wonderful work from Birgit Knoechel and Kira Bona!
@huntsmancancer.bsky.social
@danafarber.bsky.social

www.biorxiv.org/content/10.6...

02.02.2026 14:34 👍 3 🔁 4 💬 0 📌 1

Can my new hobby be receiving shipments of food from you?

01.02.2026 17:19 👍 2 🔁 0 💬 1 📌 0

This study, and Stephen’s write up on it as a professor actively teaching these skills, is fascinating.

I don’t *officially* teach coding skills, but I often find the difference between someone who’s good at their job and someone who’s marginal is *exactly* those skills that most decreased here.

31.01.2026 23:26 👍 28 🔁 16 💬 1 📌 0
"Bread & Milk" -THE ORIGINAL VIDEO-  vicdibitetto.net
"Bread & Milk" -THE ORIGINAL VIDEO- vicdibitetto.net YouTube video by Vic Dibitetto

Still one of my favorites: youtube.com/shorts/i6zaV...

23.01.2026 02:30 👍 1 🔁 0 💬 0 📌 0

First ever‽

21.01.2026 00:34 👍 0 🔁 0 💬 1 📌 0

Honestly, that sounds like somebody just trying to remind you why you love the place.

18.01.2026 01:53 👍 1 🔁 0 💬 0 📌 0

If only they were so passive.

17.01.2026 11:31 👍 1 🔁 0 💬 0 📌 0

The other night I dreamed I had adopted two baby ostriches.

Just thought you might want to know.

14.01.2026 00:27 👍 0 🔁 0 💬 0 📌 0

I’m sure it was online in 2000 but maybe we mailed transcripts?

27.12.2025 14:04 👍 1 🔁 0 💬 0 📌 0

@recdiffs.bsky.social An excellent variation on blaming the dog. @siracusa.social @hotdogsladies.bsky.social

27.12.2025 03:27 👍 1 🔁 0 💬 0 📌 0

You mean The Donald J Trump and The Washington Monument

19.12.2025 20:44 👍 2 🔁 0 💬 0 📌 0

I think you mean The Donald J. Trump and The Giant and Very Normal Looking Penis

19.12.2025 20:43 👍 0 🔁 0 💬 0 📌 0