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Lewis MacKenzie

@lemackz

Upconversion nanoparticles, optical biosensors, chiral spectroscopy, scicomm, blood oxygen | bass player | uranium glass collector Group website: www.mackenzie-lab.org he/him | Glasgow | Expect typos

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Latest posts by Lewis MacKenzie @lemackz

I get the sense that mirror life really polarises opinions.πŸ˜…

12.03.2026 16:30 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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About β€” Mirror Biology Dialogues Fund

I just found out about the Mirror Biology Dialogues Fund - promoting research into the risks and mitigation of mirror life #mirrorlife #chirality #chemsky #biology

www.mbdialogues.org/about

12.03.2026 16:13 πŸ‘ 0 πŸ” 0 πŸ’¬ 2 πŸ“Œ 1
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What's 2026 like? Do you still use clipart?

No, powerpoint now has hundreds of tiny people expressing all sorts of various emotions in high resolution

12.03.2026 11:48 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

I'm mainly here for the science feed, which is a less sassy version of my science-focused old-school twitter

11.03.2026 21:59 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

"Detecting and controlling #mirrorlife is especially difficult because almost all diagnostic tests and tools are designed to find regular life forms"

The good news is that we have figured out an assay for mirror life - see our #ChemRxiv #preprint
chemrxiv.org/doi/full/10....

#ChemSky #Biology

11.03.2026 16:23 πŸ‘ 4 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Mirror Life | Secretary-General’s Scientific Advisory Board

Even the United Nations are writing security briefings are #mirrorlife threats! #ChemSky #chiral #chirality #biology

www.un.org/scientific-a...

11.03.2026 16:20 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 1
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πŸ§ͺ Schottky defects occur in ionic crystals. They are pairs of point defects, where a vacancy at a cation site is matched by a vacancy at an anion site, preserving the charge balance.
Here's my two dimensional paper representation of a Schottky defect in sodium chloride. #SciArt #SciComm

11.03.2026 00:16 πŸ‘ 33 πŸ” 10 πŸ’¬ 0 πŸ“Œ 1

All phones have a feature that transcribes speech to text. It works on audiobooks and podcasts. I've accidentally switched it on a few times on my android. Should be somewhere in accessibility features.

08.03.2026 23:51 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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Iran war threatens global helium supply Attacks on Qatar and the Strait of Hormuz remove one-third of the world’s helium from the market

The war in Iran has taken one-third of the world’s helium supply off the market. And if the conflict continues for more than 2 weeks, disruption for helium users could take months to resolve.

#chemsky πŸ§ͺ

07.03.2026 15:43 πŸ‘ 104 πŸ” 62 πŸ’¬ 5 πŸ“Œ 40

I appreciate the scrutiny - if you want things clarified/scrutinised further it's best to speak to corresponding author of each paper.

04.03.2026 20:14 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

For the citations... it is a very highly cited paper because it is the first in a new field of microscopy.

Obviously we don't control who cites the papers, but I am a bit confused as to why those ones are citing it. Sometimes I wonder if people are making mistakes with their reference manager? 🀷

04.03.2026 20:10 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

For the CPL spectra - well noticed by the way - I believe the pub peer puts that down to human error. Again, I didn't make that figure either and it's best to get in touch with the corresponding author.

04.03.2026 20:01 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

For the FTIR spectra, I do wonder if that could be PDF image conversion issues.

For the FTIR spectral resolution and line shapes, I'd recommend contacting the corresponding author on that one.

04.03.2026 20:00 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Howdy, happy to discuss.

I don't quite follow what you mean on the first image. Could you expand upon that?

I think the second issue has been addressed on pub peer by my co-authors?

04.03.2026 18:01 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Yeah could be in supplementary info or a data repository

04.03.2026 15:37 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Just put the "less than perfect" images in the supplementary info as validation against AI fakery. No big deal.

04.03.2026 15:37 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 1

It's a good question! We can only do what we can...

04.03.2026 13:58 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

One of the ways to deal with this is to publish the not just the best nanoparticle images, but also the zoomed-out ones showing all the imperfections! (so far) imperfections are not in the training data (i.e. "publication quality" images).

04.03.2026 12:17 πŸ‘ 5 πŸ” 1 πŸ’¬ 3 πŸ“Œ 0

don't forget that the AI assistant built into any computer can fake images of perfect nanoparticles! #Chemsky #materials #nanotech

www.nature.com/articles/s41...

04.03.2026 12:16 πŸ‘ 4 πŸ” 3 πŸ’¬ 1 πŸ“Œ 1

Likewise, on windows, holding ALT and then pressing 2 then 4 then 1 summons the 'Β±' symbol

02.03.2026 11:19 πŸ‘ 3 πŸ” 1 πŸ’¬ 3 πŸ“Œ 0

Your periodic reminder that holding ALT and then pressing 2 then 3 then 0 summons the 'Β΅' symbol

02.03.2026 11:19 πŸ‘ 19 πŸ” 2 πŸ’¬ 6 πŸ“Œ 3
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'Inversions' by Iain M. Banks. I cannot say any more without spoilers, but it is best read as part of the loose tapestry of The Culture series.

01.03.2026 22:25 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Another lovely brutalist sunset at Strathclyde Uni

27.02.2026 17:35 πŸ‘ 9 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Huge contratulations to Rebecca McGonigle for passing her PhD viva last Friday! A massive achievement for Rebecca and a landmark moment for my group too!

Thanks to the examiners Dr William Peveler (UoG), Dr Juliane Simmchen (Strathclyde), and Dr Alastair Wark for convening.

16.02.2026 11:43 πŸ‘ 12 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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A small polymerase ribozyme that can synthesize itself and its complementary strand The emergence of a chemical system capable of self-replication and evolution is a critical event in the origin of life. RNA polymerase ribozymes can replicate RNA, but their large size and structural ...

Link to the original research article in Science
www.science.org/doi/10.1126/...

16.02.2026 11:00 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Link without paywall: archive.is/D1dyl

16.02.2026 11:00 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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RNA strand that can almost self-replicate may be key to life's origins Life may have begun when RNA molecules began to replicate themselves, and now we’ve finally found an RNA molecule that is very close to being able to do this

Very cool #science story - examining a trillion RNA sequences to find a few that can almost self-replicate! #chemsky #bioscience #biology #originoflife

www.newscientist.com/article/2515...

16.02.2026 10:59 πŸ‘ 3 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Link without paywall: archive.is/D1dyl

16.02.2026 10:58 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Yeah the book is definitely enjoyable YA Sci-fi.

15.02.2026 11:46 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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If Moonbase Alpha and Snowpiercer counts, then I think the refugee fleet in Battlestar Galactica must also count. There are around 50,000 survivors which is a big town or small city.

15.02.2026 11:43 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0