OpenSourceNeuro

- Signal preprocessing, see how to handle different types of noise and cleanup your data before extracting spikes.

Stay tuned for advancements ! #Neuropixel

See how your Spikeling neuron firing action potentials would look like in a extracellular ephys setup live. Features :

- Spatial integration, see how the electrode placement relative to the neuron impacts the extracellular field recordings, determining for spike sorting. #Ephys

Spikeling v3 feature reveal : a new module ! After current clamp, voltage clamp, calcium imaging, we are implementing an extracellular tetrode recording module ! #Neuroscience #CalciumImaging

This workshop is meant to act as a facillitator to fuel collaboration between behavioural and neuronal research, an essential aspect of neuroscience.

Thanks to everyone involved ! #CalciumImaging #Neuroscience

Spikeling allows people from outside the field of Neurophysiology to grasp essential concepts such as membrane voltage dynamics, synaptic integration, patching electrophysiology, calcium imaging, and have a better understanding to relate with the electrophysiology team.

Today with the Kind Lab affiliated with the Simons Initiative for the Developping Brain @sidb-edinburgh.bsky.social at the University of Edinburgh @cmvm-edinburghuni.bsky.social, we ran a Spikeling workshop with the ethology team within the lab.
#Electrophysiology

Interplay of behaviour and neurophysiology is at the core of neuroscience, and collaboration of ethologists and neurophysiologists is crutial. #Ethology #Neurophysiology

A simple floor map (hand → spinal cord → brain) and real-time spike activity the young students could see and even hear.

A practical way to show what neurons do and what neurophysiology researchers measure.

#NeuroscienceEducation #Neurophysiology #TReNDinAfrica

Last summer in Ghana, during a @TReNDinAfrica outreach event in the exchange program between the VIB-KU Center For Neuroscience @vibneuroleuven.bsky.social and the University of Ghana, we used Spikeling to show pain propagation mechanisms to kids -

OSN promotes neuroscience access with open, low-cost tools for education, training, and outreach, especially where conventional neurophysiology setups aren’t available.

#ScienceOutreach #OpenScience

This supports state-of-the-art teaching goals: quantitative, reproducible, experiment-driven training without requiring access to expensive wet-lab infrastructure. #Neurophysiology #Electrophysiology

Students can test how sampling, kinetics, saturation, noise, and bleaching shape what imaging “means,” then export traces for standard analyses and spike inference. #TwoPhotonImaging

Spikeling’s imaging simulation brings microscopy-grade data interpretation into the classroom by linking Vm/spikes to Ca²⁺ and fluorescence (F ; ΔF/F) in real time.

#Neuroscience #CalciumImaging

Contact us to implement Spikeling practicals at your university !
#Neurophysiology #TwoPhoton
#ComputationalNeuroscience #OpenScience #OpenHardware

Spikeling also links ephys “ground truth” (spikes/Vm) to modern imaging:

its two-photon simulation generates a fluorescence/calcium-style readout, helping students interpret 2-photon data and analysis choices when working with open resources (e.g. @Allen Institute datasets).

- but have never had the opportunity to observe or record neuronal responses in an experimental setting.

Spikeling changes that.

Around laptops and devices, students run electrophysiology-style protocols: shaping inputs, tuning frequency/intensity and see firing dynamics evolve in real time.

State-of-the-art neuroscience education shouldn’t depend on access to patch-clamp rigs or two-photon microscopes.

At the @trendcamina.bsky.social computational neuroscience & ML workshop feat. @akoumoundourou.bsky.social, students arrive with strong coding skills -

#NeuroscienceEducation #CAMINA

See how we can approach the mechanisms of seizure occurence in epilepsy with a 2-minutes Spikeling workshop ! #Epilepsy #Seizure #Neuroscience #Electrophysiology #Neurophysiology

POV : unboxing a Spikeling delivery from @opensourceneuro.com ! #Neuroscience #Education #STEM #Electrophysiology #Neurophysiology #Opensource #Spikes

Finish like a real practical: built-in tools for stimulus alignment, spike detection, and averaging—a complete experiment from stimulus to analysis, in the classroom. #Education #STEM

Flip the input polarity to teach ON vs OFF pathways (responses to light onset vs offset), then tune decay and recovery to demonstrate adaptation and sensitivity reset. #NeuroPhysiology #ElectroPhysiology #Teaching

Sensory neuroscience workshop with Spikeling — from light to spikes.

Run meaningful sensory experiments outside the wet lab: the on-board photoreceptor provides a synaptic-like input to an in-silico patched neuron.

#Neuroscience #SensoryNeuroscience

The possibilities to explore with Spikeling are endless ! #Neuroscience #Education #Teaching #InformationTheory #NeuronalCoding #CognitiveNeuroscience #CognitivePsychology #Electrophysiology #Neurophysiology

Different membrane potential properties can encode discrete aspects of information though action potential firing, from a basic binary ON/OFF encoding to temporality and history encoding. #Teaching #InformationTheory #NeuronalCoding #CognitiveNeuroscience

Spikeling allows to learn about neurophysiology from many angles, it is easy to see how different neuronal subtypes encode stimulus input information. #Neuroscience #Education #Teaching #InformationTheory

See how easy it is to plug and play with a buzzing Spikeling. This is just a teaser, follow us for more demos of the numerous cool functionalities and applications of Spikeling ! #Neuroscience #Electrophysiology #Teaching #Education

Last week @opensourceneuro.com was at Université Côte d'Azur for a Spikeling demo. Thanks to the Molecular and Cellular Pharmacology Institute affiliated with CNRS-INSERM for the invite ! #Spikeling #Neuroscience #Education

GitHub - OpenSourceNeuro/Spikeling: A hardware implementation of spiking neurons for neuroscience teaching and outreach A hardware implementation of spiking neurons for neuroscience teaching and outreach - OpenSourceNeuro/Spikeling

We make key neurophysiology concepts practical, repeatable, and affordable, so more students can learn by doing.

If you teach neuroscience or run practical sessions, we’d love feedback, issues, and contributions !

Web Page: www.opensourceneuro.com/index.php/sp...

#STEMEducation

We aim to push neuroscience training toward state-of-the-art standards for the next generation of researchers: experimental thinking, quantitative analysis, reproducible workflows, and modern neurotech literacy—grounded in open hardware and open science. #Neurophysiology #GlobalHealth

Spikeling is an open-source teaching device built to democratize neurophysiology education.
In academia—especially in low-resource and low-income settings—hands-on electrophysiology is often limited by cost and logistics. #OpenScience #OpenHardware #NeuroscienceEducation