This #ASNJASN explores how DDR1 contributes to AKI by affecting mitochondria. Researchers found that DDR1 moves to mitochondria in damaged kidneys, increasing harmful reactive oxygen species (mtROS) and cell death. hhttps://kidney.pub/JASN1045 Ignes
This #ASNJASN article finds that adoption of the 2021 KDIGO BP guideline remained limited in real-world practice. As of 2024, nearly 4 in 5 patients with CKD had systolic BP above the new guideline target. Read the full article here: kidney.pub/JASN1046 Pradeep Natarajan
The March issue of CJASN is now available online! Topics covered this month include: - Transplant Outcomes in Pediatric ANCA Associated Vasculitis - Perspective on Accounting for APOL1 Genotype in RCTs - and more Check out the issue here: kidney.pub/CJASN-0326 #ASNJASN Cover by Matarneh et al.
Coming soon: the next ASN Kidney Health Guidance on Conservative Management in People with Kidney Failure! Check out past #ASNJASN Kidney Health Guidance and related content here: https://bit.ly/JASNKHG
The March issue of JASN is now available online! Topics covered this month include: - Podocyte STAT3 Drives KLF4-Related Podocytopathy - Loop Diuretic Intensification vs Thiazide Addition - and more Check out the issue here: kidney.pub/JASN-0326 #ASNJASN Cover by Zhu et al.
In this #ASNJASN study, ultrasound localization microscopy provided a safe and reliable in vivo assessment of the human intrarenal microvasculature. Read more: kidney.pub/JASN0968
This #ASNJASN study demonstrates that disruptions in Polycystin ciliary trafficking and channel function are common causes of ADPKD. Read more #BasicResearch: kidney.pub/JASN1008
This prospective study in #ASNJASN of 976 adults measured the association between subclinical primary aldosteronism and kidney outcomes. Read more: kidney.pub/JASN1039 Rémi Goupil
This #ASNJASN study explored the impact of calorie restriction on Autosomal Dominant Tubulointerstitial Kidney Disease (ADTKD) caused by UMOD mutations. Read more, and explore #BasicResearch: kidney.pub/JASN1032 Luca Rampoldi
This #ASNJASN study explored the effects of losing the NUP93 gene in mice, which led to progressive kidney disease. Read more: kidney.pub/JASN0964 #BasicResearch
The February issue of JASN is now available online! Topics covered this month include: - Validation of Klinrisk for CKD Progression - Expression of Female Gsta2 Gene in Male Mice in AKI - and more Check out the issue here: kidney.pub/JASN-0226 #ASNJASN Cover by Cheng et al.
This #ASNJASN study reviewed and analyzed data from 93 studies involving over 62,000 participants to explore the link between kidney function and Alzheimer's disease biomarkers. Read the new systematic review and meta-analysis: kidney.pub/JASN1007
This #ASNJASN study used volume electron microscopy to create detailed 3D models of podocytes, which are key cells in the kidney's filtration system. This research highlights the adaptability of podocytes, offering insights into how kidneys cope with aging. kidney.pub/JASN0979 #BasicReserch
This #ASNJASN study explored how enalapril, a common RAAS inhibitor used for kidney protection, affects different cell types in the kidney, particularly focusing on the distal nephron. Read more: kidney.pub/JASN0995 #BasicResearch Katalin Susztak Michael S. Balzer
In this #ASNJASN study, authors determine if skeletal muscle produces FGF23 in response to phosphate elevations. #BasicResearch kidney.pub/JASN0963
This study in #ASNJASN examined changes in peritoneal dialysis (PD) use across different US communities from 2011 to 2020. Researchers analyzed data from 755 Health Service Areas and over 1 million patients to see if PD use expanded in areas with historically low usage. kidney.pub/JASN0989
This study in #ASNJASN examined the link between preeclampsia during pregnancy and early signs of kidney damage in women. Check out the full article: kidney.pub/JASN1001
In an #ASNJASN study of patients with kidney failure on hemodialysis, sphingolipids with long-chain fatty acids were strongly associated with greater risk of death, especially cardiovascular death. Read the article: kidney.pub/JASN0982 UW Nephrology
This #ASNJASN Designing Clinical Trials article highlights key themes from the Patient Focused
Drug Development (PFDD) guidance, clinical outcome assessments, and other key resources with recommendations for clinical trial design in kidney disease. Read more: kidney.pub/JASN0981
In this #ASNJASN "Mechanisms of Kidney Diseases" article, authors discuss the technical capabilities and challenges in mapping the spatial distribution of normal and abnormal developmental processes in the kidney. Read the article: kidney.pub/JASN0951
Join us in celebrating a year of highlights across all four ASN publications: #ASNJASN #ASNCJASN #ASNKidney360 and #ASNKidneyNews through our year-end report. Check it out! kidney.pub/2025Annua...
What are the latest insights on treating hepatorenal syndrome? Read this #ASNJASN Clinical Nephrology Insight article: kidney.pub/JASN0920
Autosomal dominant polycystic kidney disease (ADPKD) is linked to mutations in PKD1 and PKD2 genes, affecting cation channel complexes in kidney cell cilia. This #ASNJASN study explored ways to increase these complexes in cilia to prevent kidney cyst formation: kidney.pub/JASN0942
Autosomal dominant polycystic kidney disease (ADPKD) is a common cause of kidney failure. This #ASNJASN study developed a multivariable predictive model for progression to kidney failure: kidney.pub/JASN0950 @alanyuneph.bsky.social
This #ASNJASN study examined the relationship between bone mineral density, kidney function, and fracture risk in postmenopausal women. Read more: kidney.pub/JASN0960
Join us in celebrating a year of highlights across all four ASN publications: #ASNJASN #ASNCJASN #ASNKidney360 and #ASNKidneyNews through our year-end report. Check it out! kidney.pub/2025Annua...
In this new #ASNJASN perspective live today, authors discuss a new model for NIH indirect costs that they developed: the FAIR model. Read more: kidney.pub/JASN1003
How Does Dietary Potassium Influence Blood Pressure? Check out this #ASNJASN Mechanisms of Kidney Disease article: kidney.pub/JASN0988
This #ASNJASN review synthesizes recent insights into the structural–metabolic coupling in podocytes, dissects the mechanisms of metabolic derangement in disease contexts, and discusses promising therapeutic strategies aimed at restoring metabolic homeostasis. Check it out! kidney.pub/JASN0917
