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ReVision Implant wins FDA breakthrough nod for vision-restoring BCI ReVision Implant announced today that it received FDA breakthrough device designation for its Occular visual cortical prosthesis.

ReVision Implant receives FDA breakthrough device designation for its Occular visual cortical prosthesis

www.massdevice.com/revision-imp...

#BionicVision #BCI #NeuroTech

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Patient Registry | Science Corporation Join the Science Patient Registry to be considered for participation in our vision loss research studies.

Science's PRIMA clinical trials are expanding to Australia, and will include inherited retinal diseases, such as Stargardt disease and retinitis pigmentosa.

Join the patient registry here: patients.science.xyz

#BionicVision #Neurotech #blindness #AMD #stargardt

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Artifact‐Minimizing Ultrathin Transparent Electrodes Fabricated via iCVD for In Vivo Optogenetic Stimulation and Neural Signal Monitoring of Primary Visual Cortex We present ultrathin flexible transparent electrodes through iCVD-enabled molecular control of 10 nm gold films on poly(dimethylaminomethylstyrene). In vivo validation demonstrated photoelectric…

New research from the Maesoon Im lab introduces transparent electrodes that reduce photoelectric artifacts by 74%, enabling simultaneous optical stimulation and electrical recording using neural interfaces

#BionicVision #NeuroTech #Engineering

advanced.onlinelibrary.wiley.com/doi/full/10....

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What happens when a neural network controls electrical stimulation delivered directly to the brain?

In our new JNE paper we answer an important question: how do we know these models are safe?

bionicvisionlab.org/publications...

Full details in the thread below 👇

#BionicVision #NeuroTech #BCI

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Virtual retina could help with vision loss - Surrey University A Surrey-based study details how the retina can build its structure from one type of stem cell.

A Surrey-based study details how the #retina can build its structure from one type of stem cell: "Our simulations show how genetically identical cells can, through intrinsic bias and chance, self-organise into the retina's highly ordered layers." 🧠 🧪

www.bbc.com/news/article...

#BionicVision

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Computer Chips in Our Bodies Could Be the Future of Medicine The brain-computer interface is real. It's changing lives—and could soon change the world.

“AMD patients in our clinical trial were able to read and write again, not just letter by letter but word by word,” said Daniel Palanker, professor of ophthalmology and electrical engineering at Stanford University.

#BionicVision #PRIMA #BCI #NeuroTech

time.com/7330887/brai...

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bionic-vision.org | Research Spotlights | Yossi Mandel In a new Advanced Functional Materials paper, Prof. Yossi Mandel and colleagues unveiled a hybrid retinal prosthesis that fuses living neurons with a high-density electrode array. By nestling human st...

What if retinal prostheses could speak the brain’s language? 👁️🧠🧪

Prof. Yossi Mandel and team built a hybrid implant that merges neurons and electrodes to restore high-acuity sight.

New Data Drop interview ↓
www.bionic-vision.org/research-spo...

#BionicVision #Neurotech #Blindness

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Subretinal Photovoltaic Implant to Restore Vision in Geographic Atrophy Due to AMD | NEJM Geographic atrophy due to age-related macular degeneration (AMD) is the leading cause of irreversible blindness and affects more than 5 million persons worldwide. No therapies to restore vision in ...

🚨 Breakthrough alert: A new study in the NEJM reports that the PRIMA subretinal implant helped restore meaningful central vision in ~80% of participants with advanced geographic atrophy (an untreatable form of #AMD).

www.nejm.org/doi/10.1056/...

#BionicVision #NeuroTech

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Long-Term Outcomes and Patient Experiences With the Argus II Retinal Prosthesis System - Jonathan D. Shirian, Alex Yuan, Aleksandra Rachitskaya, 2025 Purpose: To evaluate the long-term outcomes and experiences of patients with the Argus II retinal prosthesis in individuals with advanced-stage retinitis pigmen...

What happens years after the implant?

A new study from Cleveland Clinic follows 13 Argus II users long-term. None still use the device - but nearly half say they’d do it again. A powerful reminder of both the promise and the burden of early #BionicVision.

doi.org/10.1177/2474...

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bionic-vision.org | Research Spotlights | Philip Hessburg Drawing from his vast experience in ophthalmology and as a cornerstone of the Detroit Institute of Ophthalmology, Dr. Philip Hessburg discusses his pioneering work, the ever-evolving landscape of…

🕯️ One year ago, we lost Dr. Philip Hessburg—founder of The Eye and the Chip and a lifelong champion of bionic vision. His legacy continues to inspire.

📖 Read our 2023 interview:
🔗 www.bionic-vision.org/research-spo...
#BionicVision #VisionScience #InMemoriam

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Deep Learning-Based Control of Electrically Evoked Activity in Human Visual Cortex Visual cortical prostheses offer a promising path to sight restoration, but current systems elicit crude, variable percepts and rely on manual electrode-by-electrode calibration that does not scale.…

🚨 New preprint: Researchers from ETH Zurich, UMH Elche, and UCSB report the first data-driven control of a visual cortical prosthesis in a blind human.

Deep learning enabled more efficient, stable stimulation - and argues for closed-loop designs.

doi.org/10.1101/2025...

#BionicVision #NeuroTech

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Diagram of the experimental setup for measuring electrically evoked neural activity. A stimulation pattern is chosen across electrodes on a Utah array (left). Selected electrodes deliver 167 ms trains of 50 pulses at 300 Hz (middle left), sent via stimulator and amplifier into the visual cortex of a participant (middle). Neural signals are recorded before and after stimulation across all channels, producing multi-unit activity traces (MUAe). The difference between pre- and post-stimulation activity (ΔMUAe) is computed (middle right) and visualized as a heatmap across electrodes, showing localized increases in neural responses (right).

Diagram of the experimental setup for measuring electrically evoked neural activity. A stimulation pattern is chosen across electrodes on a Utah array (left). Selected electrodes deliver 167 ms trains of 50 pulses at 300 Hz (middle left), sent via stimulator and amplifier into the visual cortex of a participant (middle). Neural signals are recorded before and after stimulation across all channels, producing multi-unit activity traces (MUAe). The difference between pre- and post-stimulation activity (ΔMUAe) is computed (middle right) and visualized as a heatmap across electrodes, showing localized increases in neural responses (right).

Many in #BionicVision have tried to map stimulation → perception, but cortical responses are nonlinear and drift day to day.

So we turned to 🧠 data: >6,000 stim-response pairs over 4 months in a blind volunteer, letting a model learn the rules from the data.

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bionic-vision.org | Research Spotlights | Lauren Ayton Prof. Lauren Ayton has built a remarkably multifaceted career in vision science: from her early days as an optometrist to leading the clinical team at Bionic Vision Australia, guiding trials at Bionic...

New Pathways interview on bionic-vision.org: Prof. Lauren Ayton’s journey from clinic to leadership in #BionicVision, from early “switch-on” moments to shaping the future of #SightRestoration.

Read here 👉 www.bionic-vision.org/research-spo...

#Blindness #NeuroTech #BCI #GeneTherapy

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bionic-vision.org | Events | The Eye & The Chip '25 The Eye & The Chip '25: 14th World Research Congress on Artificial Vision

Eye & the Chip '25 is almost here: Sept 28-30, Southfield, MI. Top minds in #BionicVision (neurobiology, nanoelectronics & more) will be presenting advances that bring artificial vision closer to reality.

See the full list of confirmed speakers:
www.bionic-vision.org/events/eye-c...

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Bionic Vision - Advancing Sight Restoration Discover cutting-edge research, events, and insights in bionic vision and sight restoration.

👁️⚡ Data Drop: We spoke with Dr. Jiayi Zhang about her recent Science paper on tellurium nanowire retinal implants: restoring vision and extending it to IR. No power source. No cables.

“Are we treating blindness—or enhancing human capability?”

🔗 www.bionic-vision.org/research-spo...
#BionicVision

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Bionic Vision - Advancing Sight Restoration Discover cutting-edge research, events, and insights in bionic vision and sight restoration.

👁️⚡ I spoke with Dr. Jiayi Zhang about her Science paper on tellurium nanowire retinal implants—restoring vision and extending it into the infrared, no external power required.

New materials, new spectrum, new possibilities.
🔗 www.bionic-vision.org/research-spo...

#BionicVision #NeuroTech

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Program – EMBC 2025 Loading...

At #EMBC2025? Come check out two talks from my lab in tomorrow’s Sensory Neuroprostheses session!

🗓️ Thurs July 17 · 8-10AM · Room B3 M3-4
🧠 Efficient threshold estimation
🧑🔬 Deep human-in-the-loop optimization

🔗 embc.embs.org/2025/program/
#BionicVision #NeuroTech #IEEE #EMBS

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Evaluating deep human-in-the-loop optimization for retinal implants using sighted participants | Bionic Vision Lab We evaluate HILO using sighted participants viewing simulated prosthetic vision to assess its ability to optimize stimulation strategies under realistic conditions.

🎓 Proud of our undergrad(!) Eirini Schoinas for leading this:
bionicvisionlab.org/publications...

🧠 Human-in-the-loop optimization (HILO) works in silico—but does it hold up with real people?
✅ HILO outperformed naïve and deep encoders
🔁 A step toward personalized #BionicVision

#EMBC2025

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Program – EMBC 2025 Loading...

👁️⚡ Headed to #EMBC2025? Catch two of our lab’s talks on optimizing retinal implants!

📍 Sensory Neuroprostheses
🗓️ Thurs July 17 · 8-10AM · Room B3 M3-4
🧠 Efficient threshold estimation
🧑🔬 Deep human-in-the-loop optimization

🔗 embc.embs.org/2025/program/
#BionicVision #NeuroTech #IEEE #EMBS #Retina

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A group of surgeons in blue scrubs and surgical masks are performing a procedure in a clinical wetlab setting. Dr. Muqit (seated) operates under a ZEISS ARTEVO® 850 surgical microscope, with Dr. others observing and assisting nearby. A large monitor and medical equipment are visible in the background, along with surgical instruments on a sterile table. The environment is dimly lit, with overhead lights providing focused illumination on the surgical field.

A group of surgeons in blue scrubs and surgical masks are performing a procedure in a clinical wetlab setting. Dr. Muqit (seated) operates under a ZEISS ARTEVO® 850 surgical microscope, with Dr. others observing and assisting nearby. A large monitor and medical equipment are visible in the background, along with surgical instruments on a sterile table. The environment is dimly lit, with overhead lights providing focused illumination on the surgical field.

A surgeon in blue scrubs, surgical gloves, and a hair cover is seated and operating under a ZEISS ARTEVO® 850 surgical microscope. He is performing a delicate procedure on a blue surgical model using forceps, while another masked assistant supports from behind. The operating table is covered with a sterile green drape, and medical tubing and instruments are visible around the setup. The environment is dimly lit, highlighting the precision of the surgical training.

A surgeon in blue scrubs, surgical gloves, and a hair cover is seated and operating under a ZEISS ARTEVO® 850 surgical microscope. He is performing a delicate procedure on a blue surgical model using forceps, while another masked assistant supports from behind. The operating table is covered with a sterile green drape, and medical tubing and instruments are visible around the setup. The environment is dimly lit, highlighting the precision of the surgical training.

A wide view of a surgical training room shows multiple surgeons in blue scrubs and masks working around a ZEISS ARTEVO® 850 digital microscope. One seated surgeon is actively operating on a subretinal surgery model, while others observe and assist. A large overhead visualization arm and a table with imaging and surgical equipment are prominently visible. The lighting is dim except for the illuminated surgical field, emphasizing the precision and focus of the wetlab environment.

A wide view of a surgical training room shows multiple surgeons in blue scrubs and masks working around a ZEISS ARTEVO® 850 digital microscope. One seated surgeon is actively operating on a subretinal surgery model, while others observe and assist. A large overhead visualization arm and a table with imaging and surgical equipment are prominently visible. The lighting is dim except for the illuminated surgical field, emphasizing the precision and focus of the wetlab environment.

Two surgeons in blue scrubs and surgical caps are seated at a ZEISS ARTEVO® 850 digital microscope in a dimly lit operating room. A large monitor displays a high-resolution OCT scan, showing detailed cross-sections of ocular tissue. A green surgical drape, tubing, and imaging equipment are visible around the operating station. The scene highlights the integration of real-time imaging in subretinal surgical training.

Two surgeons in blue scrubs and surgical caps are seated at a ZEISS ARTEVO® 850 digital microscope in a dimly lit operating room. A large monitor displays a high-resolution OCT scan, showing detailed cross-sections of ocular tissue. A green surgical drape, tubing, and imaging equipment are visible around the operating station. The scene highlights the integration of real-time imaging in subretinal surgical training.

🔬👁️ The next-gen #PRIMA chip in action: subretinal surgery training in 🇩🇪 with the Science Corps team, Prof. Yannick Le Mer, and Prof. Dr. Lars-Olof Hattenbach.

3D digital visualization + iOCT = a powerful combo for precision subretinal implant work.
#BionicVision #NeuroTech

📸 via Dr. Mahi Muqit

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Prof. da Cruz argues the real legacy of first-gen devices is:
– safety + biotolerance
– validated test methods (FLORA, navigation tasks)
– a foundation to build on

We know how to test now.
We just need better tools.

#BionicVision #ClinicalTrials

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👁️📉 “Have we lost our way?”

In a sobering but essential read, Prof. da Cruz reflects on the rise, retreat, and future of retinal prostheses:
“Performance didn’t transfer to daily life—and the field stalled.”

🔒https://onlinelibrary.wiley.com/doi/10.1111/ceo.14564

#BionicVision #BCI #NeuroTech

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Thrilled to see this one hit the presses! 🎉

One of the final gems from Dr. Justin Kasowski’s dissertatio, showing how checkerboard rastering boosts perceptual clarity in simulated prosthetic vision. 👁️⚡️

#BionicVision #NeuroTech

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This matters. Checkerboard rastering:

✔️ works across tasks
✔️ requires no fancy calibration
✔️ is hardware-agnostic

A low-cost, high-impact tweak that could make future visual prostheses more usable and more intuitive.

#BionicVision #BCI #NeuroTech

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Raster patterns in simulated prosthetic vision. On the left, a natural scene of a yellow car is shown, followed by its transformation into a prosthetic vision simulation using a 10×10 grid of electrodes (red dots). Below this, a zoomed-in example shows the resulting phosphene pattern. To comply with safety constraints, electrodes are divided into five spatial groups activated sequentially across ~220 milliseconds. Each row represents a different raster pattern: vertical (columns activated left to right), horizontal (rows top to bottom), checkerboard (spatially maximized separation), and random (reshuffled every five frames). For each pattern, five panels show how the scene is progressively built across the five raster groups. Vertical and horizontal patterns show strong directional streaking. Checkerboard shows more uniform activation and perceptual clarity. Random appears spatially noisy and inconsistent.

Raster patterns in simulated prosthetic vision. On the left, a natural scene of a yellow car is shown, followed by its transformation into a prosthetic vision simulation using a 10×10 grid of electrodes (red dots). Below this, a zoomed-in example shows the resulting phosphene pattern. To comply with safety constraints, electrodes are divided into five spatial groups activated sequentially across ~220 milliseconds. Each row represents a different raster pattern: vertical (columns activated left to right), horizontal (rows top to bottom), checkerboard (spatially maximized separation), and random (reshuffled every five frames). For each pattern, five panels show how the scene is progressively built across the five raster groups. Vertical and horizontal patterns show strong directional streaking. Checkerboard shows more uniform activation and perceptual clarity. Random appears spatially noisy and inconsistent.

👁️🧠 New paper alert!

We show that checkerboard-style electrode activation improves perceptual clarity in simulated prosthetic vision—outperforming other patterns in both letter and motion tasks.

Less bias, more function, same safety.

🔗 doi.org/10.1088/1741...

#BionicVision #NeuroTech

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Neuralink Update, Summer 2025
Neuralink Update, Summer 2025 We’re translating neural signals into life-changing impact.Join us to build the machine that builds the machine to merge with machines.neuralink.com/careersL...

Recent update from Neuralink 👁️🧠🕹️:

- 7 participants implanted (ALS & SCI)
- First vision implant (Blindsight) planned for 2026 with deeper threads (5cm)
- 10,000 channels planned for 2027

#BionicVision #BCI #NeuroTech

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Post image Post image Post image Post image

Direct from the future. 👁️‍🗨️ This bionic eye is a stunning blend of circuits & glowing optics. Sharp focus, high-tech vibes.

www.patreon.com/posts/cybern...

#BionicEye #Cybernetic #SciFiArt #HighTech #DigitalArt #Futuristic #AIArt #ScienceFiction #TechArt #PromptArt #BionicVision

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Science Submits CE Mark Application for PRIMA Retinal Implant – A Critical Step Towards Making It Available To Patients | Science Corporation Science Corporation is a clinical-stage medical technology company.

👁️🧠 Big step forward for #BionicVision: Science has submitted a CE mark application for the PRIMA retinal implant. If approved, it would be the first #NeuroTech to treat geographic atrophy, a late-stage form of age-related macular degeneration #AMD.

🔗 science.xyz/news/prima-c...

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bionic-vision.org | Research Spotlights | Frederik Ceyssens, ReVision Implant Frederik Ceyssens is Co-Founder and CEO of ReVision Implant, the company behind Occular: a next-generation cortical prosthesis designed to restore both central and peripheral vision through ultra-flex...

👁️🧠🧪 Next on the Horizon: Frederik Ceyssens from ReVision Implant on scaling bionic vision to the cortex with Occular, a high-res, deep-brain prosthesis.

Why performance might beat invasiveness - and what comes next:
www.bionic-vision.org/research-spo...

#BionicVision #NeuroTech #BCI

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Enhanced Optogenetic Stimulation of Retinal Ganglion Cells With Assistive Electric Stimulation for Low Optical Power Artificial Vision High optical power of optogenetic stimulation may cause phototoxicity during chronic application. To lower the optical power, a hybrid approach which combines optogenetic and electric modalities has b...

Hybrid opto-electric stimulation boosts retinal spikes at lower light levels: promising for safer, longer-lasting vision restoration.
#Optogenetics #Neurotech #BionicVision 👁️🧠🧪

doi.org/10.1109/TNSR...

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