This is an exciting #perspective by our colleagues Amor Damatac II, Markéta Kaucká, Kristian Ullrich, as well as Alexander Klimovich, in #Nature Communications!
Congrats!

@marketa-kau.bsky.social @amordamatac.bsky.social

#evodevo #hourglass #embryogenesis #singlecell #development #evolution

🎉 New #CIBSS publication!

Dr. Daria @onichtchouk.bsky.social reveals how chromosome structure is organised at the very start of life. Using zebrafish, the team shows how DNA architecture forms as embryos activate their genomes.

🔗https://kurzlinks.de/gwuu

#Chromosomes #Embryogenesis #SignalsOfLife

New research in #RESPhysEnt

Embryonic exposure to heat impacts #development time, adult #morphology and #fecundity in pea #aphids
doi.org/10.1111/phen.70031

#Acyrthosiphon #Embryogenesis
@wybouw.bsky.social @tbuescher.bsky.social @tobybruce.bsky.social @wileyecology.bsky.social

How does a ball of cells become an embryo? Genes matter—but physics (forces, geometry, topology) drives self-organization. Hervé Turlier's research vision on the physics of embryogenesis👇
shorturl.at/761x9

#Embryogenesis #Biophysics #Morphogenesis
@college-de-france.fr @cnrsbiologie.bsky.social

Metabolic Origins: Steering of early developmental fate #MetabolismMondays - the Node All the world's a metabolic dance, early career scientists are leading the way! Emerging perspectives in metabolism Dr Kristina StapornwongkulX:

@kstapornwongkul.bsky.social , #newPI at @viennabiocenter.bsky.social - discussing the metabolism of embryonic development using #gastruloids. #embryogenesis
#DevBio #stemcell #glucosemetabolism

Propagation of cacao (Theobroma cacao L.) clone ‘CCN51’ using somatic embryogenesis: from pilot scale to commercial production The transition of promising technologies for the massive production of cacao trees from research to commercial scale is often difficult and expensive. As a result, the timeframe estimated for plant...

Propagation of #cacao (#Theobroma cacao) clone ‘CCN51’ using somatic #embryogenesis: from pilot scale to commercial production.
To rediscover one of our most read articles in JHSB 98:6, visit: doi.org/10.1080/1462...

#SE #InVitro #Cocoa #CCN51

The role of m6A RNA methylation in the maintenance of X chromosome inactivation and X-to-autosome dosage compensation in early embryonic lineages In this article, Gayen and colleagues demonstrate that m6A RNA methylation is dispensable for the maintenance of X chromosome inactivation; however, it partly contributes to the maintenance of X to au...

Delighted to share our publication in @stemcellreports.bsky.social on the role of #m6A_RNA methylation in #Xchromosome dosage compensation during #embryogenesis, jointly driven by Hemant and @barorunumi.bsky.social. 🔗 www.cell.com/stem-cell-re...
@isscr.org
🧵

p-Enh deletion disrupts NMPs’ bi-potency and biases lineage commitment toward PSM fate across in vitro, in vivo, and in silico models

Cell Regen Research | Posterior enhancer (p-Enh) maintains neuromesodermal progenitor bi-potency during gastrulation! Deletion biases fate toward presomitic mesoderm, thereby disrupting spinal cord development. #StemCells #Embryogenesis
🔗 More at: doi.org/10.1186/s136...

XCI-ited to share that @Runumi from our lab recently attended the Gordon Research Conference on "Epigenetic Variation: Mechanisms and Impact across Systems" held in Barcelona, Spain. She presented her work on role of #m6A-RNA in #embryogenesis and dosage compensation #X-inactivation.

A continuous totipotent-like cell-based embryo model recapitulates mouse embryogenesis from zygotic genome activation to gastrulation - Nature Cell Biology The authors identify a chemical cocktail to generate totipotent-like cells, which they then use to build an embryo model. This model captures a developmental spectrum from early embryogenesis to post-...

☕The authors identify a chemical cocktail to generate #totipotent - like cells, which they then use to build an #embryo model. This model captures a developmental spectrum from early #embryogenesis to post-implantation events.
bit.ly/4oHxUZp

📃Yukiko Nakaya, Tatsuo Shibata & co. in Lab for Physical Biology revealed a meshwork-like mode of collective cell migration in chick #embryogenesis using quantitative analysis of #liveimaging data, topological data analysis, and theoretical modeling.

In @elife.bsky.social
👉 doi.org/10.7554/eLif...

Runumi, from our lab, had a fantastic week at the @embo.org Epitranscriptome workshop at EMBL Heidelberg! She presented her work on the role of m6A RNA modification in #embryogenesis #stemcell specification and #Xinactivation. #EMBOEpitrans
Thanks to IISc, ANRF-India, DBT-India, @insdb.bsky.social

TemporalVAE: atlas-assisted temporal mapping of time-series single-cell transcriptomes during embryogenesis. #SingleCell #scRNAseq #TimeSeries #Embryogenesis #DeepLearning #Genomics #Bioinformatics @natcellbio.nature.com
www.nature.com/articles/s41...

Epigenetics Update - Remodelling bivalent chromatin is essential for mouse peri-implantation embryogenesis go.nature.com/4o38m8G

#Epigenetics #Bivalency #Chromatin #Embryogenesis
---

Perfect for cancer, immunology, and aging research; epigenometech.com

Are you a biologist with a research interest in #embryogenesis or synthetic biology? Join our upcoming residential scientific meeting in Brighton on the topic of generative biology: royalsociety.org/science-even... ‪@jcornwallscoones.bsky.social ‪@dbenzinger.bsky.social @cellysally.bsky.social

Epigenetics Update - Preventing CpG hypermethylation in oocytes safeguards mouse development bit.ly/41u5adm

Antoine H.F.M. Peters (FMI/ University of Basel) reporting in Dev Cell

#Epigenetics #DNAme #DNAm #DNAdemethylation #Embryogenesis
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Discover the breakthrough at epigenometech.com

A photo of the Cloisters at St John’s College, Cambridge University

Just arrived in #Cambridge at St John’s College for the 53rd Cambridge Ophthalmological Symposium focused on one of my specialties #Embryogenesis and the #Eye.

Heading to Biomatter: From Cytoskeleton to Embryo in Arolla?
Don’t miss our PhD student @prajwal08.bsky.social at poster #44! Come hear about his cool work on #osmoregulation during #embryogenesis.

#Arolla2025

Metabolic regulation of key developmental events during mammalian embryogenesis - Nature Cell Biology This Review discusses the intricate relationship between metabolism and embryogenesis, highlighting the orchestration of key developmental processes by metabolites and signalling molecules that provid...

Anyone here interested in #metabolism in #devbio ?
We recently published a Review article by Jin Zhang & co discussing the relationship between metabolism and #embryogenesis. Enjoy the read! :D
👉https://rdcu.be/eADIT
www.nature.com/articles/s41...

🏖️Our August issue's out!
Cover: Flexibility of #autophagy initiation

👉🏼Review on #metabolism in #embryogenesis #devbio
👉🏼Review on #DNArepair
🔬 #ribosomes #neurodevelopment #mitophagy #ferroptosis #stemcells #epigenetics #leukemia #antitumor immunity & more!
www.nature.com/ncb/volumes/...

Only 3 days remain to register for THE #developmentalbiology #conference in Europe, the V4SDB Meeting 2025, taking place on the 5th-7th September 2025 in 📷⛰️!
Join us: v4sdb2025.img.cas.cz/registration...
#morphogenesis #stemcells #evodevo #organoids #modeling #embryogenesis

📢Only 21 days remain to register for THE #developmentalbiology #conference in Europe, the V4SDB Meeting 2025, that will take place on the 5th-7th September 2025 in 🇸🇰⛰️!
Join us: v4sdb2025.img.cas.cz/registration...
#morphogenesis #stemcells #evodevo #organoids #modeling #embryogenesis

Development presents... Wednesday 9 July 15:00 BST, chaired by Alex Eve. Talk 1: Lakshmi Balasubramaniam (Gurdon Institute) ‘Tissue spreading couples matrix remodelling during avian gastrulation’ Talk 2: André Dias (Universitat Pompeu Fabra) ‘Opposing Nodal and Wnt signalling activities govern the emergence of the mammalian body plan’ Talk 3: Nikhil Mishra (Institute of Science and Technology Austria) ‘Geometry-driven asymmetric cell divisions pattern cell cycles and zygotic genome activation in the zebrafish embryo’

Sign up to attend our next Development presents... webinar on early #embryogenesis, featuring talks from @lakshmib02.bsky.social, @dias-andre.bsky.social ‬and @nikhil-mishra.bsky.social

📅Wed 9 July 15:00BST (UTC+1)

Register here: us02web.zoom.us/webinar/regi...

#DevBio @dev-journal.bsky.social

Are you a biologist with a research interest in #embryogenesis or synthetic biology? Join our upcoming residential scientific meeting in Brighton on the topic of generative biology: royalsociety.org/science-even... ‪@jcornwallscoones.bsky.social ‪@dbenzinger.bsky.social @cellysally.bsky.social

New Jersey Makes Progress in Reducing Unnecessary Cesarean Deliveries and Supporting Maternal Health | Newswise Researchers with the Rutgers School of Public Health found that New Jersey reduced low-risk Cesarean deliveries, bringing it closer to meeting the federal Department of Health and Human Services’ targ...

New Jersey Makes Progress in Reducing Unnecessary Cesarean Deliveries and Supporting Maternal Health
www.newswise.com/articles/new...
#regenerativemedicine #biobots #Anthrobots #developmentalbiology #embryogenesis

A Reset on the Cellular Aging Clock | Newswise Using adult human cells to produce novel multicellular organisms, researchers find that the cells express both ancient genes, which are shared with our predecessors as far back as single celled organi...

A Reset on the Cellular Aging Clock
www.newswise.com/articles/a-r...
#regenerativemedicine #biobots #Anthrobots #developmentalbiology #embryogenesis

Development presents... Wednesday 9 July 15:00 BST, chaired by Alex Eve. Talk 1: Lakshmi Balasubramaniam (Gurdon Institute) ‘Tissue spreading couples matrix remodelling during avian gastrulation’ Talk 2: André Dias (Universitat Pompeu Fabra) ‘Opposing Nodal and Wnt signalling activities govern the emergence of the mammalian body plan’ Talk 3: Nikhil Mishra (Institute of Science and Technology Austria) ‘Geometry-driven asymmetric cell divisions pattern cell cycles and zygotic genome activation in the zebrafish embryo’

Sign up to attend our next Development presents... webinar on early #embryogenesis, featuring talks from @lakshmib02.bsky.social‬, @dias-andre.bsky.social ‬and @nikhil-mishra.bsky.social.

📅Wed 9 July 15:00BST (UTC+1)

Register here: us02web.zoom.us/webinar/regi...

#DevBio @dev-journal.bsky.social

Left, from top to bottom: Mouse: An internal fertilizer where sperm entry initiates sustained Ca2+ oscillations via sperm-derived PLCζ. Drosophila: An internal fertilizer, but egg activation triggered by mechanical stimuli following ovulation precedes fertilization. Amphibians: External fertilizing species where sperm interaction with an unidentified oolemma receptor triggers the Ca2+ wave. Zebrafish: An external fertilizing species where Ca2+ release and egg activation occur upon spawning and following contact with water and activation of a protease-activated receptor 2a (Par-2a). Top right: Speculative localization of Par-2a and associated G proteins in the zebrafish egg cortex before fertilization; the activating serine proteases and precise ligand changes remain unidentified. Bottom right: Post-activation Ca2+ dynamics in zebrafish embryos: each cleavage division is driven by a localized Ca2+ rise at the cleavage furrow. The extent to which Par-2a and IP3 signaling contribute to these post-activation Ca2+ transients will require additional confirmation. Shown: 1-cell zygote, 2-cell, and 4-cell stages.

The calcium surge that starts #embryogenesis varies across species. This Primer explores a @plosbiology.org study of #zebrafish, revealing that protease-activated receptors mediate a calcium signal that initiates #egg activation before #sperm entry 🧪 Paper: plos.io/467nrzY Primer: plos.io/3TuRvy1

Left, from top to bottom: Mouse: An internal fertilizer where sperm entry initiates sustained Ca2+ oscillations via sperm-derived PLCζ. Drosophila: An internal fertilizer, but egg activation triggered by mechanical stimuli following ovulation precedes fertilization. Amphibians: External fertilizing species where sperm interaction with an unidentified oolemma receptor triggers the Ca2+ wave. Zebrafish: An external fertilizing species where Ca2+ release and egg activation occur upon spawning and following contact with water and activation of a protease-activated receptor 2a (Par-2a). Top right: Speculative localization of Par-2a and associated G proteins in the zebrafish egg cortex before fertilization; the activating serine proteases and precise ligand changes remain unidentified. Bottom right: Post-activation Ca2+ dynamics in zebrafish embryos: each cleavage division is driven by a localized Ca2+ rise at the cleavage furrow. The extent to which Par-2a and IP3 signaling contribute to these post-activation Ca2+ transients will require additional confirmation. Shown: 1-cell zygote, 2-cell, and 4-cell stages.

The calcium surge that starts #embryogenesis varies across species. This Primer explores a @plosbiology.org study of #zebrafish, revealing that protease-activated receptors mediate a calcium signal that initiates #egg activation before #sperm entry 🧪 Paper: plos.io/467nrzY Primer: plos.io/3TuRvy1

Left, from top to bottom: Mouse: An internal fertilizer where sperm entry initiates sustained Ca2+ oscillations via sperm-derived PLCζ. Drosophila: An internal fertilizer, but egg activation triggered by mechanical stimuli following ovulation precedes fertilization. Amphibians: External fertilizing species where sperm interaction with an unidentified oolemma receptor triggers the Ca2+ wave. Zebrafish: An external fertilizing species where Ca2+ release and egg activation occur upon spawning and following contact with water and activation of a protease-activated receptor 2a (Par-2a). Top right: Speculative localization of Par-2a and associated G proteins in the zebrafish egg cortex before fertilization; the activating serine proteases and precise ligand changes remain unidentified. Bottom right: Post-activation Ca2+ dynamics in zebrafish embryos: each cleavage division is driven by a localized Ca2+ rise at the cleavage furrow. The extent to which Par-2a and IP3 signaling contribute to these post-activation Ca2+ transients will require additional confirmation. Shown: 1-cell zygote, 2-cell, and 4-cell stages.

The calcium surge that starts #embryogenesis varies across species. This Primer explores a @plosbiology.org study of #zebrafish, revealing that protease-activated receptors mediate a calcium signal that initiates #egg activation before #sperm entry 🧪 Paper: plos.io/467nrzY Primer: plos.io/3TuRvy1