A dynamic model for Waddington’s landscape accounting for cell-to-cell communication Waddington’s landscape provides a conceptual model for developmental processes. It is the basis of various mathematical models describing cell maturat…

A dynamic model for #Waddington's #landscape accounting for #cell-to-cell #communication. #MathBiosci @unibonn.bsky.social #HasenauerLab #SchlitzerLab; #Dendritic #cell #activation; #Stem #cell #regeneration shorturl.at/IEMsy

Developmental programming by maternal obesity alters offspring lifespan and immune responses in a diet- and sex-specific manner Maternal obesity is a growing health concern that predisposes offspring to metabolic dysfunction, immune system alterations, and neurodegenerative dis…

Developmental #programming by #maternal #obesity alters offspring #lifespan and immune responses in a diet- and sex-specific manner. #Cells&Development @masslab.bsky.social #HasenauerLab #ThieleLab #BauerLab @unibonn.bsky.social #Hemocytes; #Macrophages; #Metabolism; #Plasmatocytes. rb.gy/pe6d15

Congrats to our PIs @masslab.bsky.social & #HasenauerLab on their latest work uncovering the crosstalk between #Kupffer #Cells and #Hepatocytes in the context of maternal obesity.

A great example of macrophage-driven communication shaping tissue physiology
👇 #Macrophages #Liver #Crosstalk

Integrative modeling of the spread of serious infectious diseases and corresponding wastewater dynamics The COVID-19 pandemic has emphasized the critical need for accurate disease modeling to inform public health interventions. Traditional reliance on co…

Integrative #modeling of the spread of serious #infectious #diseases and corresponding #wastewater dynamics; #Epidemics #HasenauerLab @unibonn.bsky.social; #Agent-based model; #Hydrodynamic model shorturl.at/M9iqS

Assessment of uncertainty quantification in universal differential equations | Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences Scientific machine learning is a new class of approaches that integrate physical knowledge and mechanistic models with data-driven techniques to uncover the governing equations of complex processes. A...

Assessment of #uncertainty #quantification in #universal #differential #equations #PhilosTransAMathPhysEngSci #HasenauerLab @unibonn.bsky.social #scientific #machine #learning shorturl.at/UCDpU

Loss formulations for assumption-free neural inference of SDE coefficient functions - npj Systems Biology and Applications npj Systems Biology and Applications - Loss formulations for assumption-free neural inference of SDE coefficient functions

Loss formulations for assumption-free neural inference of #SDE #coefficient #functions #npj-SystemsBiologyandApplications #HasenauerLab @unibonn.bsky.social shorturl.at/hkDsB