We’re excited to announce a strategic collaboration pairing Biocare Medical’s ONCORE Pro X™ automated staining instrument with our MoxiePlex™ multispectral imaging system. Learn more about our partnership: https://ow.ly/RI8h50XlcqN

#SpatialBiology #MultiplexImaging #CancerResearch

High Throughput Hyperspectral and Multiplexed Super-Resolution Fluorescence Imaging by SP-STORM | Stefan Prechtl 𝗦𝗣-𝗦𝗧𝗢𝗥𝗠 (𝗦𝗽𝗲𝗰𝘁𝗿𝗮𝗹-𝗣𝗵𝗮𝘀𝗼𝗿 𝗦𝗧𝗢𝗥𝗠) 𝘗𝘳𝘦𝘗𝘳𝘪𝘯𝘵 𝘸𝘰𝘳𝘵𝘩 𝘢 𝘭𝘰𝘰𝘬 “𝗛𝗶𝗴𝗵 𝗧𝗵𝗿𝗼𝘂𝗴𝗵𝗽𝘂𝘁 𝗛𝘆𝗽𝗲𝗿𝘀𝗽𝗲𝗰𝘁𝗿𝗮𝗹 𝗮𝗻𝗱 𝗠𝘂𝗹𝘁𝗶𝗽𝗹𝗲𝘅𝗲𝗱 𝗦𝘂𝗽𝗲𝗿-𝗥𝗲𝘀𝗼𝗹𝘂𝘁𝗶𝗼𝗻 𝗙𝗹𝘂𝗼𝗿𝗲𝘀𝗰𝗲𝗻𝗰𝗲 𝗜𝗺𝗮𝗴𝗶𝗻𝗴 𝗯𝘆 𝗦𝗣-𝗦𝗧𝗢𝗥𝗠” (𝘗𝘰𝘵𝘵 𝘦𝘵 𝘢𝘭., 𝘣𝘪𝘰𝘙𝘹𝘪𝘷, 𝘚𝘦𝘱𝘵 2025 — https://lnkd.in/d5smSTUN ) A clever implementation of spectral-phasor analysis directly in hardware — achieving simultaneous five-color super-resolution imaging within about a minute. By merging sine/cosine filter optics with dSTORM principles, the method reduces spectral crosstalk (<5 %) and removes the need for sequential channel switching. The hardware-level multiplexing is a decisive step toward practical multi-target SMLM, though the current proof remains 2D and relies on custom filter sets. 𝘈 𝘵𝘢𝘯𝘨𝘪𝘣𝘭𝘦 𝘢𝘥𝘷𝘢𝘯𝘤𝘦 𝘪𝘯 𝘮𝘶𝘭𝘵𝘪𝘱𝘭𝘦𝘹𝘦𝘥 𝘱𝘩𝘦𝘯𝘰𝘵𝘺𝘱𝘪𝘯𝘨 — 𝘰𝘯𝘦 𝘵𝘩𝘢𝘵 𝘤𝘰𝘶𝘭𝘥 𝘳𝘦𝘴𝘩𝘢𝘱𝘦 𝘩𝘰𝘸 𝘴𝘱𝘦𝘤𝘵𝘳𝘢𝘭 𝘪𝘯𝘧𝘰𝘳𝘮𝘢𝘵𝘪𝘰𝘯 𝘪𝘴 𝘪𝘯𝘵𝘦𝘨𝘳𝘢𝘵𝘦𝘥 𝘪𝘯𝘵𝘰 𝘏𝘊𝘐 𝘸𝘰𝘳𝘬𝘧𝘭𝘰𝘸𝘴 𝘰𝘯𝘤𝘦 𝘴𝘤𝘢𝘭𝘦𝘥 𝘵𝘰 𝟥𝘋 𝘢𝘯𝘥 𝘭𝘪𝘷𝘦 𝘪𝘮𝘢𝘨𝘪𝘯𝘨. #SPSTORM #SpectralImaging #SMLM #Multiplex #HighContent #FluorescenceMicroscopy #bioRxiv

Five-color SR in one shot — strong step toward scalable multiplexed phenotyping.
Next challenge: 3D + live-cell stability.

#SPSTORM #MultiplexImaging #HCI

✨ That’s a wrap on The Power of Multiplexed Imaging!
A full week of hands-on sessions, inspiring lectures, a great seminar, and data analysis!
Huge thanks to all participants for your energy. Can’t wait for the next edition — stay tuned! 🔬🌈
#MultiplexImaging #SpatialBiology

✨ Reminiscing about last year’s multiplexed imaging course—such a fantastic experience! 🤩 We were thrilled to have @colinchulab.bsky.social, along with all the students & guests! Truly inspiring days of learning. Big things coming—stay tuned! 👀🚀🔬 #SpatialBiology #MultiplexImaging

Spatial characterization of immune cells within a NSCLC tumor. 🔬 Image courtesy of Courtney Todorov, @neogenomics.bsky.social. Image taken on the CyteFinder II Instrument.

➡️ View all images from RareCyte's 2025 Calendar Contest, rarecyte.com/imagecontest/

#MultiplexImaging #Immunofluorescence

Beautiful Orion images from Simon Goldstein, La Jolla Institute for Immunology (@lji.org)! Thrilled to feature both images in our 2025 calendar. 🎉

🟣 Mouse ileum spiral
🔵 Human lung tumor with dense immune aggregates

#SpatialBiology #MultiplexImaging #Florescence

✨ Image Spotlight: 17-channel imaging of Pancreas Ductal Adenocarcinoma using the Orion Platform. Image courtesy of Estefania Quesada Masachs, U Miami.

View the whole slide image and biomarker panel for this sample: images.rarecyte.com/Q131-pancreas

#SpatialBiology #MultiplexImaging #RareCyte

Bridging the Gap: Insights from Mouse and Human Models in Pancreatic Cancer Research Guest Speaker: Marco Erreni, Ph D, Humanitas Research Hospital

Webinar: Bridging the Gap: Insights from Mouse and Human Models in Pancreatic Cancer Research. Guest Speaker: Marco Erreni, Ph D, Humanitas Milano

my.demio.com/ref/qABk0lBp...

#PDAC #SpatialBio #IMC #Multipleximaging #SpatialProteomics @standardbiology.bsky.social

opening new avenues for understanding the tumor microenvironment. Congratulations to first author Kaoutar Ait-Ahmad and the stellar multiplex imaging team at OHSU! #cancerneuroscience #prostatecancer #spatialprofiling #multipleximaging #neuronalinnervation

Wow! What a big day for #multipleximaging and #spatialbio! I am proud to have played a role in the genesis of this field in I-O. And more to come! @standardbiology.bsky.social

Dr. Christopher Kunney At Iotech Consulting Moderated our #AI in Screening and Detection with Drs. Ameen Salahudeen @uicancercenter.bsky.social and Lecia Sequist at MGH. They talked about #bias, #ML, drift, #multipleximaging, and #SYBIL in #lungcancer. #LCSM #LDCT #LCHES24 #SCHEQ