New protocol 🚨
Co-culture RealDRG™ sensory neurons with RealDHN™ dorsal horn neurons on the eNUVIO OMEGA4 to model functional pain circuits and sensory–spinal connectivity.
Flexible workflow: use RealDRG™ alone or swap in your cell type of choice.
#CompleteTheCircuit #NotYourAverageNeuron
New Human Trigeminal Neurons for Migraine Research!
Phase-contrast images from our newest human iPSC-derived trigeminal neuron lots show high neuronal purity achieved without the need for mitomycin C.
#NotYourAverageNeuron #pain
🎥 A glimpse into our 7-day directed differentiation of human iPSC-derived dorsal horn neurons. Fast. Reproducible. Ready for pain pathway discovery.
#NotYourAverageNeuron #CompleteTheCircuit #neuroscience #drugdiscovery #iPSC #dorsalhorn #painresearch
Motor neurons alone can't explain ALS or CMT. Schwann Cell Precursors reveal how disrupted glial-neuronal crosstalk drives disease. Co-cultures model early pathogenesis, glial dysfunction, and myelination defects more accurately.
#CompleteTheCircuit #NotYourAverageNeuron
Add These Publications to Your Reading List 📚
Explore all publications featuring Anatomic’s products in one place — a fast way to find relevant assays and new applications.
See how our models are advancing discovery: www.anatomic.com/publications
#CompleteTheCircuit #NotYourAverageNeuron
Exciting synaptic insights! 🟢
Using Anatomic’s nociceptors & dorsal horn neurons, VGLUT2 (green) shows glutamate at synapses, while TUJ1 (red) highlights neurons.
#CompleteTheCircuit #SensoryNeurons #PainResearch #DorsalHornNeurons #NotYourAverageNeuron
Keepin’ it local🤙🏼We attended the 3rd Minnesota Organoid Symposium put on by the University of Minnesota and Mayo Clinic earlier this week. Big shoutout to our Scitech intern Devanshi, who gave her first poster presentation!
#NotYourAverageNeuron #CIPN #StemCells
🌉 Hello, San Francisco! Catch Vincent Truong at the Axion BioSystems World Tour on April 17! He’ll share how advanced hiPSC-based models are transforming #pain, #ALS & #CMT research.
🔗 Register now → axionbiosystems.com/axion-world-...
#AxionWorldTour #hiPSC #Neuroscience #NotYourAverageNeuron
💡 Integrating Schwann cell precursors (SCPs) into motor neuron (MN) cultures enhances relevance by replicating human physiology. As SCPs mature, they migrate and align along axons, visualized via S100b/SOX10 (SCPs) and TUJ1 (MNs) staining.
#CompleteTheCircuit #NotYourAverageNeuron #ALSResearch
💎Check-out the purity💎 Images of co-cultures of RealSCP, hiPSC-derived Schwann cell precursors, and RealDRG, hiPSC-derived sensory neurons, generated without the need for genetic engineering or Mitomycin C.
#CompleteTheCircuit #NotYourAverageNeuron
It’s always tough to pick favorites when there’s so much exciting data to explore! 🤩 We have compiled our favorite data from over the years onto a new page for your easy access.
Check out our data highlights page at www.anatomic.com/datahighlights
#CompleteTheCircuit #NotYourAverageNeuron
🧒🏻👧🏽👦🏼👩🏽🦱Multiple donors. Same process. Sensory neurons derived from hiPSC lines (both healthy and diseased) express key ion channel targets for pain - NaV1.7, NaV1.8, and TRPV1.
#NotYourAverageNeuron #CompleteTheCircuit #DiseaseModeling #PainResearch
Sensory neurons and Schwann cells are better together❣️
Whether you are single or have date night plans, this is a scientific love story that you can study this Valentine’s day.
#CompleteTheCircuit #NotYourAverageNeuron #PainResearch #CoCultures #CMT
Motor neurons 🤝 Schwann cell precursors
Adding SCPs enhances ALS models by increasing physiological relevance. As co-cultures mature, SCPs align with axons—the first step of myelination!
Learn more: support@anatomic.com
#CompleteTheCircuit #NotYourAverageNeuron
🔗 Decoding Motor-Schwann Interactions! 🔬
ICC reveals neuron morphology & Schwann cell distribution, while qPCR tracks myelination markers over time.
Schedule a call to learn more!
#CompleteTheCircuit #PainResearch #NotYourAverageNeuron
Did you know Schwann cells are the most abundant glial cells in the peripheral nervous system? 💡
In these images, hiPSC-derived Schwann cell precursors (S100b, SOX10) align increasingly with hiPSC-derived motor neurons (TUJ1) over time in culture.
#ALS #CompleteTheCircuit #NotYourAverageNeuron
Anatomical relevance = physiological relevance
In a local collab with Dr. Sunny Chan at UMN, we generated a same-donor tri-culture NMJ: hiPSC-derived Schwann cell precursors, motor neurons, & skeletal muscle.
#CompletingTheCircuit #NotYourAverageNeuron #stemcells #neuroscience #ALS
