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Will you be at USCAP in San Antonio? Visit us at Booth 656, March 23–25, 2026! Dr. Nat Pernick will be at our booth on Monday and Tuesday (23rd–24th).

See what’s in store at our booth: www.pathologyoutlines.com/pathoutconfe...

#USCAP2026 #USCAP #Pathology #PathologyOutlines #PathSky

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Image of the Week!

Contributed by: Ammar Aljefri, M.B.B.S.
Textbook topic: Stains & CD markers
Diagnosis: Metastasis of endometrioid endometrial adenocarcinoma in omentum (L1-CAM)
Textbook topic link: www.pathologyoutlines.com/topic/stains...

#Pathology #PathologyOutlines #PathSky

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Image of the Week!

Contributed by: Dre Barnachea, M.D.
Textbook topic: Skin melanocytic tumor
Diagnosis: Sentinel node biopsy-melanoma
Textbook topic link: www.pathologyoutlines.com/topic/skintu...

#Pathology #PathologyOutlines #PathSky

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(Image Quiz, continued)

A. C4d0 (extensive positivity in the renal interstitium)
B. C4d0 (marked background staining of collagen)
C. C4d0 (no staining of peritubular capillaries)
D. C4d3 (diffuse positivity in > 50% of peritubular capillaries)

See link in comments.

#Pathology #PathologyOutlines

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Dr. Nat Pernick, founder and owner of PathologyOutlines.com, believes businesses should embrace charitable activities as a core part of their mission. One way PathologyOutlines.com puts this commitment into action is through scholarships.

Info: buff.ly/xX7RfUD

#PathologyOutlines #Scholarships

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📣 Tell us what you think! Please share feedback about our website via the brief survey linked in the comments.

#Pathology #PathologyOutlines #PathSky

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Image of the Week!

Contributed by: Serena Ammendola, M.D.
Textbook topic: CNS & pituitary tumors
Diagnosis: Melanoma
Textbook topic link: www.pathologyoutlines.com/topic/cnstum...

#Pathology #PathologyOutlines #PathSky

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Will you be at USCAP in San Antonio next month? Visit us at Booth 656, March 23–25, 2026! Dr. Nat Pernick will be at our booth on Monday and Tuesday (23rd–24th).

See what’s in store at our booth: buff.ly/owyLqDY

#USCAP2026 #USCAP #Pathology #PathologyConference #PathologyOutlines #PathSky

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Case of the Month: A 50 year old man with decompensated hepatic cirrhosis due to alcohol use disorder and hepatorenal syndrome is being evaluated for a possible liver transplant. Pertinent laboratory values are shown on the Case page. (Continued in thread)

#Pathology #PathologyOutlines #Diagnosis

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Image of the Week!

Contributed by: Debra L. Zynger, M.D.
Textbook topic: Adrenal gland & paraganglia
Diagnosis: Composite pheochromocytoma and paraganglioma
Textbook topic link: www.pathologyoutlines.com/topic/adrena...

#Pathology #PathologyOutlines #PathSky

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Image Quiz! A 14 year old boy presents with a unilateral hyperpigmented plaque with irregular borders on the upper chest. The lesion is associated with increased coarse hair growth over the area. What is the most likely diagnosis?

(Continued in thread)

#Pathology #PathologyOutlines

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From margin notes back then to a globally trusted resource today, it’s been an incredible 25-year journey for PathologyOutlines.com.

Explore our interactive timeline to see the milestones that shaped PathologyOutlines.com: buff.ly/sn8E9mh

#Pathology #PathologyOutlines #25thAnniversary #PathSky

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Essay: “My Male Breast Cancer, Part 6”, by Dr. Nat Pernick

Part 6 of this series discusses Dr. Pernick’s subsequent drug therapy for male breast cancer.

Access here: buff.ly/gJjbgvc
Follow Curing Cancer Network: buff.ly/npW2JwB

#Cancer #CuringCancerNetwork #Pathology #PathologyOutlines #PathSky

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Dr. Pernick started a new textbook on the Curing Cancer Network home page, titled "How Cancer Arises". There may be overlap with PathologyOutlines.com, but this textbook is being developed independently.

Info: buff.ly/9F3uFuM

#CancerResearch #CuringCancerNetwork #Pathology #PathologyOutlines

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Image of the Week!

Contributed by: Maria Tretiakova, M.D., Ph.D.
Textbook topic: Prostate gland & seminal vesicles
Diagnosis: Seminal vesicles–adenocarcinoma
Textbook topic link: www.pathologyoutlines.com/topic/prosta...

#Pathology #PathologyOutlines #PathSky

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We recently appointed several new editors to our Editorial Board! We welcome Dr. Anna Biernacka, Dr. Ashwini Kumar Esnakula, and Dr. Alexei Mikhailov to the Board.

Read about them here: buff.ly/quZQZ8n
Our Boards: buff.ly/JQSLJQp

#Pathology #Textbook #PathologyOutlines #PathSky

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Be like Dr. Navarro; send us your favorite PathologyOutlines.com pic! We’d love to see your favorite PathOut moments, like selfies at our conference booth or featuring our merch! Selections to be shared on our social media. Send yours: comments@pathologyoutlines.com

#Pathology #PathologyOutlines

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Image of the Week!

Contributed by: R. Peter Powell, M.D.
Textbook topic: Pancreas
Diagnosis: Duodenal neuroendocrine tumor
Textbook topic link: www.pathologyoutlines.com/topic/pancre...

#Pathology #PathologyOutlines #PathSky

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(Image Quiz, continued)

A. Borderline mucinous tumor of the ovary
B. Borderline mucinous tumor of the ovary with microinvasion
C. Mucinous adenocarcinoma of the ovary
D. Mucinous cystadenoma

Answer linked in the comments.

#Pathology #PathologyOutlines #Diagnosis

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Read our latest “What’s New in Pathology” newsletter.

January 2026 Issue: “What’s New in Molecular Genetic Pathology 2026: Emerging Biomarkers for Personalized Cancer Therapies” by Umberto Maccio, M.D., MSc., M.B.A.

Webpage: buff.ly/XAoEkz3
PDF: buff.ly/V4UfVNo

#Pathology #PathologyOutlines

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Throwback Thursday ✨️ What year did you first connect with Dr. Pernick or PathologyOutlines.com at a conference? The first of these photos is from USCAP in 2005, and the others are from various conferences in 2010–2015.

#Pathology #PathologyOutlines #ThrowbackThursday

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Image of the Week!

Contributed by: Aaron Auerbach, M.D., M.P.H.
Textbook topic: Bone marrow neoplastic
Diagnosis: Mast cell sarcoma
Textbook topic link: www.pathologyoutlines.com/topic/bonema...

#Pathology #PathologyOutlines

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Essay: “How Lung Cancer Arises, Based on Complexity Theory” – Dr. Nat Pernick

Access here: buff.ly/gGAL0UC
Follow Curing Cancer Network: buff.ly/j5MuFKU

#Cancer #CancerResearch #CuringCancerNetwork #Pathology #PathologyOutlines

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Case of the Month: A 5 year old child had a syncopal event and became unresponsive on the way to the hospital. Autopsy sections are from the left ventricle and AV node. What is your diagnosis?

Follow the link in the comments for the case.

#Pathology #PathologyOutlines #Diagnosis #PathSky

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We recently appointed a new deputy editor and several new editors to our Editorial Board! We welcome Dr. Skala as our new Deputy Editor in Chief for Gynecologic Pathology and Dr. Asadbeigi, Dr. Brčić , and Dr. Parilla as Editors.

Read about them here: buff.ly/1v3PzeN

#Pathology #PathologyOutlines

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Image of the Week!

Contributed by: Seyed Salehi, M.D.
Textbook topic: Cervix
Diagnosis: Small cell neuroendocrine carcinoma
Textbook topic link: www.pathologyoutlines.com/topic/cervix...

#Pathology #PathologyOutlines #PathSky

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Image Quiz! A 4 year old boy presented with pigmented macules around the lips and oral mucosa, gynecomastia and the findings shown on the testis biopsy here. What diagnosis is most associated with this case?

(Continued in thread)

#Pathology #PathologyOutlines #Diagnosis #PathSky

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📣 Tell us what you think! Please share feedback about our website via the brief survey linked in the comments.

#Pathology #PathologyOutlines #PathSky

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Here's a look back at 2025! ✨ This reel highlights last year's key updates and milestones. The video is also available on YouTube, which is linked in the comments.

#Pathology #PathologyOutlines #YearInReview #PathSky

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Image of the Week!

Contributed by: Ayana Suzuki, Ph.D.
Textbook topic: Thyroid & parathyroid
Diagnosis: Medullary carcinoma
Textbook topic link: www.pathologyoutlines.com/topic/thyroi...

#Pathology #PathologyOutlines #PathSky

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