Tesei, Pesce & Lindorff-Larsen (2026) Computational design of intrinsically disordered proteins. Curr Opin Struct Biol 96:103210 #IDP #biophys #CompBiol #StructBiol #biophys #CompChem #chemsky 🧪
doi.org/10.1016/j.sb...

Postdoctoral Training Fellow - X-ray crystallography in Sutton | The Institute of Cancer Research View details and apply for this Postdoctoral Training Fellow - X-ray crystallography vacancy in Sutton. Salary: Dependent on relevant Postdoctoral experience. Future progression is base...

#PostDoc opportunity in X-ray #crystallography at Institute of Cancer Research (Sutton UK) duration: 18 months | closing: 08-Feb-2026 #StructBiol #oncology #DrugDiscovery #ChemPostDoc #PostDocJobs #chemsky 🧪
jobs.icr.ac.uk/vacancies/14...

Opportunity in biomolecular #NMR at AstraZeneca (Gothenburg Sweden) closing: 14-Dec-2025 #StructBiol #biophys #biochem #chemsky 🧪
astrazeneca.eightfold.ai/careers/job/...

EASTBIO: Probing allostery and dynamics in ATP phosphoribosyltransferase with ensemble and single-molecule enzymology at University of St Andrews on FindAPhD.com PhD Project - EASTBIO: Probing allostery and dynamics in ATP phosphoribosyltransferase with ensemble and single-molecule enzymology at University of St Andrews, listed on FindAPhD.com

Funded #PhD: Probing allostery and dynamics in ATP phosphoribosyltransferase with ensemble and single-molecule #enzymology at University of St Andrews (UK) duration: 4 years | closing 15-Dec-2025 #biochem #StructBiol #chemsky 🧪
www.findaphd.com/phds/project...

Opportunity for beamline scientist (XChem) at Diamond Light Source (Harwell Oxfordshire UK) ref: 11716 | closing: 09-Nov-2025 #MX #StructBiol #FBD #FBLD #FBDD #chemsky 🧪
vacancies.diamond.ac.uk/vacancy/prin...

Opportunity for beamline scientist (macromolecular crystallography) at Diamond Light Source (Harwell Oxfordshire UK) ref: 11715 | closing: 02-Nov-2025 #MX #StructBiol #chemsky 🧪
vacancies.diamond.ac.uk/vacancy/prin...

Tenure-based Research Staff Scientist Position in Computational Structural Biology ISTA (www.ista.ac.at) is seeking a highly skilled Staff Scientist in Computational Structural Biology to support and advance the Institute’s structural biology research through the development and imp...

Opportunity in computational structural biology at ISTA (Vienna Austria) duration: 5 years with possibility of permanent contract #StructBiol #cryoEM #cryoET #chemsky 🧪
ista.ac.at/en/job/tenur...

#PostDoc opportunity in molecular #biophysics and structural biology at University of Cambridge (UK) ref: PH47220 | duration: funding to 31-Dec-2028 | closing: 09-Oct-2025 #StructBiol #MolBiol #PostDocJobs #chemsky 🧪
www.jobs.cam.ac.uk/job/52745/

Three (3) Sustaining Innovation #PostDoc opportunities in fragment-based design at Astex Pharmaceuticals (Cambridge UK) ref: SI/0825 | closing: 30-Sep-2025 #FBD #FBDD #SBDD #MedChem #ChemBiol #StructBiol #ChemPostDoc #PostDocJobs #chemsky 🧪
www.cloudonlinerecruitment.co.uk/Astex/Vacanc...

Opportunity for structural biologist at Newcastle University (UK) ref: 28529 | closing: 24-Sep-2025 | duration: 12 months #StructBiol #PostDocJobs #chemsky 🧪
jobs.ncl.ac.uk/job/Newcastl...

Practical Fragments post on Erlanson et al (2025 #OpenAccess) Where and how to house big data on small fragments. Nat Commun 16:4179 DOI: 10.1038/s41467-025-59233-z #FBD #FBDD #FBLD #StructBiol #MedChem #cheminformatics #DataScience #chemsky 🧪
practicalfragments.blogspot.com/2025/07/how-...

Postdoctoral Research Assistant - UOD1951 Closing date: Tuesday 12 August 2025, 23:59

#PostDoc opportunity to study protein complexes at University of Dundee (UK) ref: UOD1951 | duration: 12 months | closing: 12-Aug-2025 #StructBiol #biophysics #TPD #PRTOTAC #MDG #PostDocJobs 🧪
www.dundee.ac.uk/work-for-us/...

WEBINAR: Leveraging deep learning to design custom protein-binding proteins Be inspired by case studies that show you how deep learning methods are speeding up the process of designing custom proteins

Last reminder- Dr Rhys Grinter webinar @rhyswg.bsky.social is on in just a couple of hours- click through to obtain the link. #proteindesign #structbiol

You can sign up for future event information and reminders here:

australian-structural-biology-computing.github.io/website/

🧶🧬

Opportunity in computational biology at Quantum-SI (Branford CT USA) #ML #CompChem #StructBiol #chemsky 🧪
www.quantum-si.com/about/career...

Senior Research Scientist, Structural Biology & Biophysics Job Description General Summary: The Structural Biology and Biophysics group at Vertex Pharmaceuticals is responsible for generating reagents as well as biophysical and structural information that is ...

Opportunity in structural biology & #biophysics at Vertex (Boston MA USA) ref: REQ-25331 | #SPR #StructBiol #chemsky 🧪
vrtx.wd501.myworkdayjobs.com/en-US/Vertex...

Macromolecular crystallography from an industrial perspective – the impact of synchrotron radiation on structure-based drug discovery Structure-based drug design has been a critical component of drug discovery for over 30 years, contributing to numerous approved drugs. The paper discusses the approach taken by AstraZeneca (Sweden) t...

Käck & Sjögren (2025) Macromolecular #crystallography from an industrial perspective – the impact of #synchrotron radiation on structure-based #DrugDiscovery | Journal of Synchrotron Radiation 32 #StructBiol #SBDD #CompChem #cheminformatics #OpenAccess #review #chemsky 🧪
doi.org/10.1107/S160...

Postdoctoral Training Fellow – X-Ray Crystallography in Sutton | The Institute of Cancer Research View details and apply for this Postdoctoral Training Fellow – X-Ray Crystallography vacancy in Sutton. Salary: Dependent on relevant Postdoctoral experience. Future progression is base...

#PostDoc opportunity in X-ray #crystallography at Institute for Cancer Research (Sutton UK) duration: 2 years | closing: 16-Mar-2025 #StructBiol #oncology #PostDocJobs 🧪
jobs.icr.ac.uk/vacancies/11...

#PostDoc position in structural biology for #DrugDiscovery at Instituto Italiano di Tecnologia (Genoa Italy) duration: 1 year | closing: 19-Feb-2025 #StructBiol #PostDocJobs #ChemPostDoc #chemsky 🧪
iit.taleo.net/careersectio...

Accelerating Drug Discovery With High‐Throughput Crystallographic Fragment Screening and Structural Enablement Crystallographic fragment screening has become highly efficient, overcoming previous challenges of low throughput and time consumption, due to advances in synchrotron technology and the establishment...

Fearon et al (2024) Accelerating #DrugDiscovery With High-Throughput #Crystallographic #Fragment Screening and Structural Enablement. Appl Res e202400192 #FBLD #FBDD #DrugDesign #MedChem #StructBiol #OpenAccess #chemsky 🧪
doi.org/10.1002/appl...

In situ studies of localisation, structure and interactions of TRPC5 ion channels at University of Leeds on FindAPhD.com PhD Project - In situ studies of localisation, structure and interactions of TRPC5 ion channels at University of Leeds, listed on FindAPhD.com

#PhD opportunity: In situ studies of localisation, structure and interactions of TRPC5 ion channels at University of Leeds (UK) closing 06-Jan-2025 #StructBiol 🧪
www.findaphd.com/phds/project...

#PostDoc opportunity in biochemical & structural characterisation of protein complexes important for #DNA repair at University of Cambridge (UK) ref: PH43820 | funding: 01-Dec-2024 to 31-May-2026 | closing 25-Nov-2024 #StructBiol #biochem #PostDocJobs #ScienceJobs 🧪
www.jobs.cam.ac.uk/job/48923/

Senior Scientist Protein and Structural Chemistry, London Discovery job in London, London, United Kingdom | Research & Development jobs at MSD Apply for Senior Scientist Protein and Structural Chemistry, London Discovery job with MSD in London, London, United Kingdom. Browse and apply for the Research & Development jobs at MSD

Opportunity in protein & structural chemistry at MSD (London UK) ref: R312134 | closing: 06-Oct-2024 #StructBiol #biophys #FBDD #FBLD #UKChemJobs #ChemJobs #ScienceJobs #chemsky 🧪
jobs.msd.com/gb/en/job/R3...

Assistant Professor - Biochemistry, Biophysics, and Structural Biology - Department of Molecular and Cell Biology University of California, Berkeley is hiring. Apply now!

Opportunity for assistant professor in biochemistry, biophysics & structural biology at University of California, Berkeley (USA) ref: JPF04562| start: 01-Jul-2025 | closing: 31-Oct-2024 #biochem #biophys #StructBiol #ChemJobs #chemsky 🧪
aprecruit.berkeley.edu/JPF04562

A Structural Comparison of Oral SARS-CoV-2 Drug Candidate Ibuzatrelvir Complexed with the Main Protease (Mpro) of SARS-CoV-2 and MERS-CoV Ibuzatrelvir (1) was recently disclosed and patented by Pfizer for the treatment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It has received fast-track status from the USA Food an...

Chen et al (JACS Au 2024) A Structural Comparison of Oral SARS-CoV-2 Drug Candidate Ibuzatrelvir Complexed with the Main #Protease (#Mpro) of SARS-CoV-2 and MERS-CoV. JACS Au #coronarvirus #antiviral #DrugDesign #StructBiol #MedChem #cheminformatics #OpenAccess #chemsky 🧪
doi.org/10.1021/jacs...

Beamline Scientist MicroMAX Your team The macromolecular crystallography (MX) group is responsible for the two beamlines BioMAX and MicroMAX and the fragment screening facility FragMAX, supporting structural biology research aim

Opportunity for #beamline scientist in macromolecular #crystallography group at Lund University (Sweden) ref: PA2024/2180 | closing 08-Sep-2024 #StructBiol 🧪
lu.varbi.com/en/what:job/...

Opportunity in #structural #bioinformatics at Astex Pharmaceutical (Cambridge UK) ref: SB/0624 | closing: 31-Jul-2024 #StructBiol #DataScience 🧪
www.cloudonlinerecruitment.co.uk/Astex/Vacanc...

Leadeth me unto Truth and delivereth me from those who have already found it A theory has only the alternative of being true or false. A model has a third possibility: it may be true, but irrelevant. With apologies to...

Updated review of Fraser & Murcko (2024) Structure is beauty, but not always truth. Cell 187:517-520 DOI:10.1016/j.cell.2024.01.003 with two safety-related references #StructBiol #ChemBiol #MedChem #DrugDiscovery #DrugDesign #chemsky 🧪
fbdd-lit.blogspot.com/2024/03/lead...

UCL – University College London UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).

Opportunity in preparation and purification of samples of human #proteins at University College London UCL (UK) ref: B02-07143 | duration: not specified | closing 12-Jul-2024 #biochem #biophys #StructBiol 🧪
www.ucl.ac.uk/work-at-ucl/...

Opportunity for machine leading scientist in design of novel macromolecules at Genentech (South San Francisco CA USA) ref: 202406-115336 #biologics #StructBiol #ML #CompChem #ChemJobs #chemsky 🧪
roche.wd3.myworkdayjobs.com/ROG-A2O-GENE...

Job Opportunity at the University of Southampton: Postdoctoral Research Fellow in Structural Proteomics

#PostDoc position in structural proteomics (multidrug #efflux pumps & #antibiotic resistance) at University of Southampton (UK) ref: 2753424BJ | 30 months fixed term | closing 09-Jul-2024 #StructBiol #ChemBiol #biochem #biophys #PostDocJobs #ChemPostDoc #chemsky 🧪
jobs.soton.ac.uk/Vacancy.aspx...