Dr. @annablakney.bsky.social’s team received $8.4 million USD to support their work revolutionizing cell therapy manufacturing and delivery methods!

🎊 This grant that will allow them to further explore and develop a delivery platform for immune #CellEngineering. Congrats! https://bit.ly/4pLRjbm

AI‑Powered Microdevice Boosts High‑Throughput Single‑Cell Delivery

The platform’s chip has up to 62,000 holes and can process thousands of cells per minute, while AI analysis rapidly evaluates ~500 cells in about 83 seconds. getnews.me/ai-powered-microdevice-b... #mechanoporation #cellengineering

#CRISPR #GenomeEngineering #GeneticModification #PrecisionGeneEditing #FunctionalGenomics #GeneTherapy #SingleCell #PrecisionCRISPR #NextGenGeneEditing #CellEngineering #CustomCellLines #CellLineDevelopment #CellManipulation #GeneticallyEngineeredCells #SyntheticBiology

Scientists 3-D printed a tiny elephant inside a cell The first structures ever 3-D printed inside living cells point to applications for biology research.

Scientists 3-D printed a tiny elephant inside a cell #Science #Biology #CellBiology #3DPrint #Biotechnology #CellEngineering

5/ 💬Let’s talk about your challenge in cell line engineering!

#GeneEditing #CRISPR #CRISPRCas9 #GenomeEngineering #GeneticModification #PrecisionGeneEditing #FunctionalGenomics #GeneTherapy #SingleCellEngineering #NextGenGeneEditing #CellEngineering #GeneticallyEngineeredCells #SyntheticBiology

📩 Drop a DM or reach out to us via our contact form to discuss your project: www.cytosurge.com/solutions/se...

#GeneEditing #CRISPRCas9 #PrecisionGeneEditing #GeneTherapy #PrecisionCRISPR #CellEngineering #CustomCellLines #CellLine #CellManipulation #SyntheticBiology #SingleCell

4/ This level of precision unlocks new possibilities in cancer biology and stem cell biology.

Because sometimes, the most important data comes from a single cell.
#BiotechInnovation #SingleCell #BiotechInnovation #GeneEditing #CRISPR #CRISPRCas9 #GeneticModification #CellEngineering

4/📍 May 5–6 | Basel
#BiotechInnovation #Biotech #SingleCell #SingleCellAnalysis #CellEngineering #MeetMeThere

#AACR #AACR2025 #oncology #cancerresearch #NGS #scRNAseq #LiveSeq #epigenetics #singlecell #genomics #cellbiology #FluidFM #CellEngineering #GeneEditing #Research #CRISPR #Innovation #Runners4Research

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📅 Book a consultation 👉
www.cytosurge.com/solutions/se...

#FluidFM 🔬 #PC3 #LNCaP #ProstateCancer #GeneEditing #SingleCell #CRISPR #CancerResearch #CellEngineering

Synthetic GPCRs for programmable sensing and control of cell behaviour | Nature Synthetic receptors that mediate antigen-dependent cell responses are transforming therapeutics, drug discovery and basic research1,2. However, established technologies such as chimeric antigen receptors3 can only detect immobilized antigens, have limited output scope and lack built-in drug control3–7. Here we engineer synthetic G-protein-coupled receptors (GPCRs) that are capable of driving a wide range of native or non-native cellular processes in response to a user-defined antigen. We achieve modular antigen gating by engineering and fusing a conditional auto-inhibitory domain onto GPCR scaffolds. Antigen binding to a fused nanobody relieves auto-inhibition and enables receptor activation by drug, thus generating programmable antigen-gated G-protein-coupled engineered receptors (PAGERs). We create PAGERs that are responsive to more than a dozen biologically and therapeutically important soluble and cell-surface antigens in a single step from corresponding nanobody binders. Different

Synthetic GPCRs revolutionize cell behavior control by sensing antigens & driving diverse processes. Advanced over CARs. #CellEngineering 🧬 PMID:39633047, Nature 2024, @Nature https://doi.org/10.1038/s41586-024-08282-3 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

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Talks also delved into #AntibodyEngineering by Dr. Janet Peper-Gabriel (Plectonic Biotech), immune #CellEngineering by Dr. Anke Fuchs (TU Dresden), and #TissueEngineering innovations by Prof. Michael Raghunath (Zurich University of Applied Sciences).

#CellTherapy #Immunotherapy #CAR_TCellTherapy #CancerImmunotherapy #CellBasedTherapies #CancerBreakthrough #NextGenTherapies #CellEngineering #GeneEditing #BiotechInnovation #OncologyResearch #ImmuneOncology #PersonalizedMedicine #TumorMicroenvironment

#BiotechInnovation
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📢New opportunity: Instructor of #Bioengineering📢

Apply here: apply.interfolio.com/148766

#AcademicChatter #AcademicSky #engineeringjobs #Biomechanics #Biomaterials #CellEngineering #TissueEngineering #biomedicalengineering