I’m excited to share our new ChemRxiv preprint describing native charge detection mass spectrometry for intact analysis of large, heterogeneous RNAs. Led by Raihana Afroz, in collaboration with @thermofishersci.bsky.social lnkd.in/gc29gYy7
#DirectMassTechnology #Orbitrap #CDMS #RNA

Our Astral has been down over 2 weeks now because of delayed parts. We have a service contract too. Anyone else having trouble getting parts or delayed repairs? #Astral #orbitrap #massspec #thermo

Any orbitrap Astral users out there having trouble with boards and digitizers crashing. These instruments have been out for nearly 2yrs now. It's frustrating on our end for sure. #massspec #orbitrap #astral #thermo

Having a blast at @icnaa2025.bsky.social . Karsa as proud supporter shown on screen, and excited to see our customers presenting #MION - #Orbitrap results.

TIC of Orbitrap

Extreme rookie question, but our lab just had a power outage and now our #Orbitrap Exploris 240 is not acquiring any data. Here's what our HeLa digest standard looks like before and after outage. Anyone know what might be going on? #teammassspec #proteomics #chemsky #scisky

Lego Orbitrap spectrometer

Lego Orbitrap spectrometer

Lego Orbitrap spectrometer

Lego Orbitrap spectrometer

@markbeekeeper.bsky.social came home with a (knock off) Lego kit for building a Thermo Orbitrap Astral Zoom Spectrometer. So I did. #legos #massspec #orbitrap fake Legos suck btw

Karsa is heading to #ASMS2025! Join us in Baltimore June 1–5 to hear about our latest work in #CIMS —from solid state Uronium ionization to non-contact sampling & pesticide detection. Reach out to meet with DM! 🧪
#MassSpectrometry #Orbitrap

Vent, move and pump six #Orbitrap instruments in day? No stress. #NewLabDay #TeamMassSpec

After one year of running smootly, we gave our #Orbitrap Exploris 240 a short break for its annual servicing procedure by #ThermoFisher. Big thanks to the maintenance engineer for his clear and instructive execution of the servicing procedure.🥇✨🌟
#MassSpectrometry #LCMSMS #Proteomics #TeamProteomics

🚀 Introducing Uronium—the first CIMS reagent generated by X-ray desorption of solid urea. It delivers ppq sensitivity to moderately polar & basic VOCs/SVOCs, with months-long stability.
🔗 Preprint: doi.org/10.26434/che...
💬 Thoughts? Drop your feedback below!
#CIMS #MassSpec #Orbitrap @helsinki.fi

Our very talented PhD student Fanzhou Kong published at nature method "Denoising Search doubles the number of #metabolite and #exposome annotations in human plasma using an #Orbitrap Astral mass spectrometer"
www.nature.com/articles/s41...
@jjjvanderhooft.bsky.social @mingxunwang.bsky.social

Mobile Orbitrap Mass Spectrometry: Stability and Performance in Motion – Karsa Historically, Orbitrap mass spectrometers have been considered large, power-intensive, and lab-bound instruments -- but times have changed!

🚀 Orbitraps on the move! The #MassSpec community rarely talks about moving Orbitraps, but a new study shows they can collect high-res data while in motion. Have you used an #Orbitrap outside the lab? Let’s start the conversation—share your experience! 🔬⚡ Read more: www.karsa.fi/resources/mo...

Our first post on this social and what an exciting one!
We had our benchtop #Orbitrap Exploris delivered.
Cannot wait to play with it and expand the resolving power of our LAP-MALDI ion source. Thank you @thermofishersci.bsky.social !

The last 8 years my group has been developing multiple strategies to characterize ADP-ribosylation. Our latest study uses in-source CID HCD for a MS/MS on the #Orbitrap Exploris to overcome caveats associated with labile PTMs.
analyticalsciencejournals.onlinelibrary.wiley.com/share/NZG9NQ...

Los Servicios Generales de investigación de la UPV/EHU consiguen la cofinanciación de los fondos FEDER para la adquisición de seis equipamientos científico-tecnológicos
www.ehu.eus/.../noticia_...
#FEDER #upvehu #equipamiento #tecnologia #europa #microscopia #espectrometria #orbitrap #nanomacro

Hey #metabolomics bluesky. Has anybody done a comparison on sensitivity of a Q-Exactive Plus vs. Exploris 480 in a metabolomics context? #massspec #massspectrometry #orbitrap And any feedback on reliability/uptime for the Exploris?

Metabolic pathways commitments affect enzymatic isotope fractionations which imprint compound and position specific isotope signatures

Our vision how #isotope #fractionation can be used to understand metabolic pathways and better exploit biological archives - #Orbitrap, #Metabolomics, #treerings, isotope #ecology, multidimensional isotopic #fingerprints- nph.onlinelibrary.wiley.com/doi/10.1111/nph.19973

New from #ThermoFisher #Orbitrap Ascend Tribrid #massspec allows deep #proteome coverage from low sample amounts, ideal for single-cell proteomics to understand heterogeneity in complex biological systems. IonOpticks TS 25cm column provided sensitive separation.
view.highspot.com/viewer/660e1...