This study shows heterologous #intranasal boosting with RBD-HR after mRNA priming enhances mucosal, humoral & #CellularImmunity against #SARSCoV2, inducing strong #NeutralizingAntibodies, SIgA, TRM cells & CD103⁺ DC activation.
#OpenAccess: doi.org/10.1016/j.ge...
Congratulations to our team of CSI PIs for the NRF CRP grant award!
This is CSI Singapore's first PI-led CRP, with Prof. Yang Zhang as the lead PI and Dr. Jun Siong Low & Dr. Yang Li serving as co-investigators. 🏆
#AIinBiology #Immunology #CellularImmunity #TCellResearch
This review highlights #DNABasedVaccines as a next-gen platform enabling in situ antigen expression to elicit humoral and #CellularImmunity, outlining design, advantages, clinical progress, and potential for safe #immunization. @utoronto.ca
#OpenAccess: doi.org/10.1016/j.ge...
Scientists develop a #RBDXBB15HR #vaccine inducing strong humoral and #CellularImmunity, boosting neutralization against #JN1 and #XBB subvariants, and showing protection against live #Omicron viruses—advancing next-gen #COVID19 vaccine strategies.
#STTT: doi.org/10.1038/s413...
The complementary mechanisms of humoral & #cellularimmunity induced by #Covid19vaccines. The results suggest that while neutralizing antibodies are crucial for effective viral control, #Tcell responses may offer an additional layer of protection when humoral responses are compromised.
🚨“Ripping bacteria to shreds” 🚨 VCP/p97, a cellular AAA-ATPase, targets and then using its tweezer like action rips apart bacteria, protecting us from infections. A thread 🦠💥#MolecularMachines #HostDefense #cellularimmunity #microbiology
@natmicrobiol.nature.com
www.nature.com/articles/s41...
Novel antiviral protein SAMD9L blocks HIV-1 and other lentiviruses 🔬🧬✨ www.news-medical.net/news/2024070... #HIV #Research #Antiviral #SAMD9L #HIV1 #VirusInhibition #CellularImmunity #Interferon #Lentiviruses #ViralTranslation #Biomedical @plos.bsky.social
Ratio between the prevalence of antibodies and the total number of reported cases in different geographical regions. The median ratio betwe corrected seroprevalence estimates from national studies and the corresponding cumulative incidence of SARS-CoV-2 infection from nine days prior. Includes studies (n = 49) from January to December 2020. Data from (Bobrovitz et al. PLos One. 2021)
#Cellularimmunity & #MolecularImmunology
Understanding & Overview the immune responses in asymptomatic #SarsCoV2 infection.
www.nature.com/articles/s41...
