β2 and β3a regulatory subunits can coassemble in the same BK channels, say Yu Zhou, Christopher Lingle (@chris-lingle.bsky.social) and colleagues @washumedicine.bsky.social: rupress.org/jgp/article/...

#CellularPhysiology #IntercellularSignaling #Biochemistry #Biophysics #IonChannels

Novel Ca²⁺ wave mechanisms in cardiac myocytes revealed by multiscale Ca²⁺ release model, report Morris Vysma, James Welsh, and Derek Laver @uni-newcastle.bsky.social: rupress.org/jgp/article/...

#CardiacMuscle #ComputationalBiology #Biophysics #IntercellularSignaling

Vysma, Welsh, and Laver @uni-newcastle.bsky.social develop a Ca²⁺ release model that reproduces store load–dependent release and Ca²⁺ waves in skinned ventricular myocytes. rupress.org/jgp/article/...

#Biophysics #CardiacMuscle #ComputationalBiology #IntercellularSignaling