🧪 Tiny molecular differences can rewrite big origin-of-life questions!
HFSP-supported research shows simple coacervate droplets could have supported early RNA chemistry, reshaping ideas about the transition from #RNA to #DNA worlds.

#OriginOfLife #sts #HFSP
🔗 zurl.co/ZMFM3

Registration Is Now Open For Origins 2026 - Astrobiology Origins 2026 is an international conference

Registration Is Now Open For Origins 2026
astrobiology.com/2026/03/regi... #astrobiology #originoflife

Sequence Motif Dynamics In RNA Pools - Astrobiology In RNA world scenarios pools of RNA oligomers form strongly interacting

Sequence Motif Dynamics In RNA Pools
astrobiology.com/2026/03/sequ... #astrobiology #originoflife #RNAWorld

Molecular Complexity Constrained Early Amino Acid Recruitment into the Genetic Code - Astrobiology Previously proposed chronologies of amino acid incorporation into the genetic code rely on consensus rankings derived from prebiotic synthesis experiments, biosynthetic pathways, or genomic trends.

Molecular Complexity Constrained Early Amino Acid Recruitment into the Genetic Code
astrobiology.com/2026/03/mole... #astrobiology #genomics #originoflife

Metrology of Complexity and Implications for the Study of the Emergence of Life - Astrobiology One of the longest standing open problems in science is how life arises from non-living matter.

Metrology of Complexity and Implications for the Study of the Emergence of Life
astrobiology.com/2026/03/metr... #astrobiology #originoflife #genomics

Life Forms Can Planet Hop On Asteroid Debris – And Survive - Astrobiology Tiny life forms tucked into debris from an asteroid hit could catapult to other planets – including Earth – and survive, a new Johns Hopkins University study finds.

Life Forms Can Planet Hop On Asteroid Debris – And Survive
astrobiology.com/2026/03/life... #astrobiology #panspermia #originoflife

Prebiotic Resource Constraints And The Origin Of Life: A Linear Logic Framework - Astrobiology The origin of life is a complex scientific problem demanding interdisciplinary approaches

Prebiotic Resource Constraints And The Origin Of Life: A Linear Logic Framework
astrobiology.com/2026/03/preb... #astrobiology #originoflife

On The Nature Of The Earliest Known Lifeforms - Astrobiology Microfossils from the Paleoarchean Eon are the oldest known evidence of life.

On The Nature Of The Earliest Known Lifeforms
astrobiology.com/2026/02/on-t... #astrobiology #OriginOfLife #evolution

A Parasitic Origin For The Ribosome? - Astrobiology Ribosomes are the components of cells that read RNA and build proteins

A Parasitic Origin For The Ribosome?
astrobiology.com/2026/02/a-pa... #astrobiology #OriginOfLife #evolution #genomics

Asgard Archaeal Origin Of Microtubules - Astrobiology Eukaryotic cells change their shapes, actively segregate their DNA and contain membrane network

Asgard Archaeal Origin Of Microtubules
astrobiology.com/2026/02/asga... #astrobiology #OriginOfLife #evolution #genomics

Emergence Of A Potentially Ancestral ATP-synthesizing Activity Under Prebiotic Amino Acid Constraints - Astrobiology The earliest enzymes are thought to have been composed of the limited amino acid repertoire available on prebiotic Earth.

Emergence Of A Potentially Ancestral ATP-synthesizing Activity Under Prebiotic Amino Acid Constraints
astrobiology.com/2026/02/emer... #astrobiology #OriginOfLife #evolution #genomics

Distinguishing Life From Non-life Via Molecular Frontier Orbital Energy Gaps - Astrobiology Amino acids (AAs) are a key target in the search for life beyond Earth due to their extensive role in the machinery of all known life

Distinguishing Life From Non-life Via Molecular Frontier Orbital Energy Gaps
astrobiology.com/2026/02/dist... #astrobiology #OriginOfLife #evolution #genomics

Experimental And Numerical Modeling Of Liposome Congregation In Meteorite Craters Of Early Earth - Astrobiology This paper provides experimental and numerical evidence supporting the occurrence of liposome congregation at the floors of meteor craters on Early Earth

Experimental And Numerical Modeling Of Liposome Congregation In Meteorite Craters Of Early Earth
astrobiology.com/2026/02/expe... #astrobiology #OriginOfLife #evolution #genomics

By constructing family trees of the oldest and most divergent forms of life, phylogeneticists have tried to push back to the last universal common ancestor (LUCA).

One such attempt created a family tree of 102 species, focusing on microorganisms, as those are the oldest forms of life. They […]

A Break In A Longstanding Mystery About The Origin Of Complex Life - Astrobiology The most widely accepted scientific explanation for the arrival of all complex life on Earth has had an unsolved mystery at its heart.

A Break In A Longstanding Mystery About The Origin Of Complex Life
astrobiology.com/2026/02/a-br... #astrobiology #AI #OriginOfLife

A Small Polymerase Ribozyme That Can Synthesize Itself And Its Complementary Strand - Astrobiology The emergence of a chemical system capable of self-replication and evolution is a critical event in the origin of life.

A Small Polymerase Ribozyme That Can Synthesize Itself And Its Complementary Strand
astrobiology.com/2026/02/a-sm... #astrobiology #genomics #synbio #originoflife

Theoretical Perspective On Synthetic Life: Learning From The Origin Of Life - Astrobiology Creating a man‐made life in the laboratory is one of life science’s most intriguing yet challenging problems.

Theoretical Perspective On Synthetic Man‐made life: Learning From The Origin Of Life
astrobiology.com/2026/02/theo... #astrobiology #synbio #biotechnology #originoflife

RNA strand that can almost self-replicate may be key to life's origins Life may have begun when RNA molecules began to replicate themselves, and now we’ve finally found an RNA molecule that is very close to being able to do this

Very cool #science story - examining a trillion RNA sequences to find a few that can almost self-replicate! #chemsky #bioscience #biology #originoflife

www.newscientist.com/article/2515...

Save the date! 🇯🇵✨
▶️ IOoL2026 — Interdisciplinary Origin of Life Meeting for Early Career Researchers
📍 Tokyo, Japan
🗓️ September 9–11, 2026
Indication of Interest form below! #IOoL26 #Japan #OriginOfLife #Astrobiology
📝 docs.google.com/forms/d/e/1F...

Multiple formation pathways for amino acids in the early Solar System based on carbon and nitrogen isotopes in asteroid Bennu samples | PNAS Samples collected from the carbonaceous near-Earth asteroid Bennu and delivered to Earth by NASA’s OSIRIS-REx mission contain organic molecules rel...

Meteorites, asteroids, and comets can host prebiotic organic compounds.

Amino acids in extraterrestrial materials originate from diverse precursor sources or formation mechanisms and/or undergo varied postformation alteration.

#Bennu ☄️ #OriginOfLife?

www.pnas.org/doi/10.1073/...

Tiny, 45 base long RNA can make copies of itself https://arstechni.ca #biochemistry #originoflife #evolution #ribozymes #Science #Biology #RNA

Can The Timing Of The Origin Of Life Be Inferred From Trends In The Growth Of Organismal Complexity? - Astrobiology The origin of life embodies two fundamental questions: how and when did life begin? It is commonly conjectured that life began on Earth around 4 billion years ago.

Can The Timing Of The Origin Of Life Be Inferred From Trends In The Growth Of Organismal Complexity?
astrobiology.com/2026/02/can-... #astrobiology #OriginOfLife #cosmology

The Phylogenetic Context For The Origin Of A Unique Purple-green Photosymbiosis - Astrobiology Symbioses are widespread in nature and have been the source of much evolutionary innovation.

The Phylogenetic Context For The Origin Of A Unique Purple-green Photosymbiosis
astrobiology.com/2026/02/the-... #astrobiology #originoflife #Microbiology

Reassessing viral origins and evolutionary placement in the tree of life - Antonie van Leeuwenhoek The quest to fit all cellular beings in one picture frame as the universal Tree of Life (ToL) has always been a daunting task for evolutionary biologists. Over the decades, ToL has emerged from a dich...

Reassessing viral origins and evolutionary placement in the tree of life
#OriginofLife #TreeofLife #Evolution #virus #phage #MicroSky
doi.org/10.1007/s104...

Did Iron Suppress Eukaryote Emergence and Early Radiation? - Astrobiology The last eukaryotic common ancestor (LECA) is widely thought to have been an oxygen-respiring organism

Did Iron Suppress Eukaryote Emergence and Early Radiation?
astrobiology.com/2026/02/did-... #astrobiology #originoflife

Curious about how life began? OoLEN is a global community for early-career researchers in origins of life and prebiotic chemistry. 🧬🌍 Connect with others across disciplines, find opportunities, and grow together. Join: oolen.org/join Tell us in the replies—what do you work on? #OriginOfLife

LIFE NASA RCN Seminar 11 February 2026 - Astrobiology Join the 2026 LIFE NASA RCN Seminar Series

LIFE NASA RCN Seminar 11 February 2026
astrobiology.com/2026/01/life... #astrobiology #astrochemistry #originoflife

What The Earliest Evidence For Life Tells Us About The Early Evolution Of The Biosphere - Astrobiology Life emerged on Earth in an ultramafic world under anaerobic conditions and conditioned by particular environmental characteristics for which no record remains.

What The Earliest Evidence For Life Tells Us About The Early Evolution Of The Biosphere
astrobiology.com/2026/01/what... #astrobiology #astrochemistry #originoflife

High-Pressure Torsion-Induced Transformation of Adenosine Monophosphate: Insights into Prebiotic Chemistry of RNA by Astronomical Impacts - Astrobiology The origin of life is yet a compelling scientific mystery that has sometimes been attributed to high-pressure impacts by small solar system bodies

High-Pressure Torsion-Induced Transformation of Adenosine Monophosphate: Insights into Prebiotic Chemistry of RNA by Astronomical Impacts
astrobiology.com/2026/01/high... #astrobiology #astrochemistry #originoflife

An interstellar energetic and non-aqueous pathway to peptide formation - Nature Astronomy The formation of glycylglycine, a simple peptide molecule, is possible under non-aqueous interstellar conditions, according to laboratory experiments. Thus, complex organics with biological relevance may predate planetary accretion.

here's the paper about those interstellar peptides: https://www.nature.com/articles/s41550-025-02765-7
#science #astrobiology #originOfLife