#quotes #books #booksky #excerpts #citations #behave #sapolsky #behavior #brain #neurobiology #psychology #emotion #sex #orgasm #prefrontalcortex
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#PrefrontalCortex
Posts tagged #PrefrontalCortex on Bluesky
Spatiotemporal molecular and cellular atlas of mouse PFC during postnatal development. Top left: UMAP of all cells in mouse PFC from scRNA-seq data, colored by cell subtypes. Im, immature. Top right: UMAP of all cells in mouse PFC from scRNA-seq data, colored by time stages. Bottom left: Spatial distribution of all cell subtypes in mouse PFC from P1 stereo-seq data. Bottom right: Spatial distribution of all cell subtypes in mouse PFC from adult stereo-seq data.
The #PrefrontalCortex is key for higher cognitive functions, but how do its circuits mature? This study provides a #transcriptomic resource for the mouse #PFC over 84 days of development, revealing cell population dynamics & expression of #psychiatric risk genes
@plosbiology.org 🧪 plos.io/45bhRLU
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Spatiotemporal molecular and cellular atlas of mouse PFC during postnatal development. Top left: UMAP of all cells in mouse PFC from scRNA-seq data, colored by cell subtypes. Im, immature. Top right: UMAP of all cells in mouse PFC from scRNA-seq data, colored by time stages. Bottom left: Spatial distribution of all cell subtypes in mouse PFC from P1 stereo-seq data. Bottom right: Spatial distribution of all cell subtypes in mouse PFC from adult stereo-seq data.
The #PrefrontalCortex is key for higher cognitive functions, but how do its circuits mature? This study provides a #transcriptomic resource for the mouse #PFC over 84 days of development, revealing cell population dynamics & expression of #psychiatric risk genes
@plosbiology.org 🧪 plos.io/45bhRLU
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Spatiotemporal molecular and cellular atlas of mouse PFC during postnatal development. Top left: UMAP of all cells in mouse PFC from scRNA-seq data, colored by cell subtypes. Im, immature. Top right: UMAP of all cells in mouse PFC from scRNA-seq data, colored by time stages. Bottom left: Spatial distribution of all cell subtypes in mouse PFC from P1 stereo-seq data. Bottom right: Spatial distribution of all cell subtypes in mouse PFC from adult stereo-seq data.
The #PrefrontalCortex is key for higher cognitive functions, but how do its circuits mature? This study provides a #transcriptomic resource for the mouse #PFC over 84 days of development, revealing cell population dynamics & expression of #psychiatric risk genes @plosbiology.org 🧪 plos.io/45bhRLU
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By Yafei Yuan, Guanghao Li, Haoran Ren & Wei Chen
Published April 19, 2021
#Phenomics #fNIRS #CognitiveScience #Neuroscience #BrainHealth #LightTherapy #StroopTask #Neuroimaging #PrefrontalCortex #HumanCognition #Bioengineering #Optogenetics #WorkplaceWellness #MentalPerformance #ResearchHighlight
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A painting of a woman with a serious look on her face gazing slightly off to the left. Caption: Dear God, I ask you to illuminate the prefrontal cortex of all humanity. Amen.
I really don’t ask for much.
Dear God, I ask you to illuminate the prefrontal cortex of all humanity. Amen.
😃
#art #memes #rational #reason #CriticalThinking #PrefrontalCortex #humanity
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Monosynaptic retrograde tracing from hippocampus proper shows no cells originating from nucleus reuniens (NRe), unless the starter cells are present in subiculum region. Left: Injection site for dorsal CA1 and viral spreads for the helper virus (green cells). B and D, Injection site of a dCA1 injection: green cells contain helper virus and red cells are pseudotyped rabies virus positive and starter cells (yellow) shown closer on the inset, shown by arrowheads. C and E, No cells found in any thalamic section containing NRe.
Excitatory input from #PrefrontalCortex to #hippocampus pyramidal cells is believed to be mediated through the thalamic nucleus reuniens. @mickcraig.bsky.social &co show in rodents that this brain pathway is unexpectedly minor, contrary to assumptions in the field @plosbiology.org 🧪 plos.io/48u6mle
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Monosynaptic retrograde tracing from hippocampus proper shows no cells originating from nucleus reuniens (NRe), unless the starter cells are present in subiculum region. Left: Injection site for dorsal CA1 and viral spreads for the helper virus (green cells). B and D, Injection site of a dCA1 injection: green cells contain helper virus and red cells are pseudotyped rabies virus positive and starter cells (yellow) shown closer on the inset, shown by arrowheads. C and E, No cells found in any thalamic section containing NRe.
Excitatory input from #PrefrontalCortex to #hippocampus pyramidal cells is believed to be mediated through the thalamic nucleus reuniens. @mickcraig.bsky.social &co show in rodents that this brain pathway is unexpectedly minor, contrary to assumptions in the field @plosbiology.org 🧪 plos.io/48u6mle
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Monosynaptic retrograde tracing from hippocampus proper shows no cells originating from nucleus reuniens (NRe), unless the starter cells are present in subiculum region. Left: Injection site for dorsal CA1 and viral spreads for the helper virus (green cells). B and D, Injection site of a dCA1 injection: green cells contain helper virus and red cells are pseudotyped rabies virus positive and starter cells (yellow) shown closer on the inset, shown by arrowheads. C and E, No cells found in any thalamic section containing NRe.
Excitatory input from #PrefrontalCortex to #hippocampus pyramidal cells is believed to be mediated through the thalamic nucleus reuniens. @mickcraig.bsky.social &co show in rodents that this brain pathway is unexpectedly minor, contrary to assumptions in the field @plosbiology.org 🧪 plos.io/48u6mle
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Left: An example image of a filled PV interneuron showing putative autapses with white arrows. Note that all autapses are present in close distance to the soma. Right: Pie charts depicting the percentage of cells showing (1) both structural and physiological autapses, (2) no structural nor physiological autapses, and (3) only structural autapses. Note that only mice that underwent juvenile demyelination have PV interneurons which show structural autapses but no autaptic response.
What role does #myelination play in #PrefrontalCortex development? This study shows that juvenile #demyelination disrupts PV #interneuron firing & self-inhibition, revealing a developmental window where myelination is essential for long-term cortical function @plosbiology.org 🧪 plos.io/4mI4lVO
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Left: An example image of a filled PV interneuron showing putative autapses with white arrows. Note that all autapses are present in close distance to the soma. Right: Pie charts depicting the percentage of cells showing (1) both structural and physiological autapses, (2) no structural nor physiological autapses, and (3) only structural autapses. Note that only mice that underwent juvenile demyelination have PV interneurons which show structural autapses but no autaptic response.
What role does #myelination play in #PrefrontalCortex development? This study shows that juvenile #demyelination disrupts PV #interneuron firing & self-inhibition, revealing a developmental window where myelination is essential for long-term cortical function @plosbiology.org 🧪 plos.io/4mI4lVO
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Left: An example image of a filled PV interneuron showing putative autapses with white arrows. Note that all autapses are present in close distance to the soma. Right: Pie charts depicting the percentage of cells showing (1) both structural and physiological autapses, (2) no structural nor physiological autapses, and (3) only structural autapses. Note that only mice that underwent juvenile demyelination have PV interneurons which show structural autapses but no autaptic response.
What role does #myelination play in #PrefrontalCortex development? This study shows that juvenile #demyelination disrupts PV #interneuron firing & self-inhibition, revealing a developmental window where myelination is essential for long-term cortical function @plosbiology.org 🧪 plos.io/4mI4lVO
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Something I always wondered about people with #tourettes and #ticdisorders:
We're almost always empaths.
The part of our brain - the #prefrontalcortex - responsible for #empathy is slightly larger than usual while the part of our brain in our #basalganglia regulating motor planning/control […]
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“The #prefrontalcortex is the #brain region that is most sensitive to the detrimental effects of stress exposure.”
I’m convinced the effects of #ConstantStress caused by #InsatiableCapitalistGreed has made #America a nation of brain damaged ghouls.
#VivaVenezuela
www.nature.com/articles/nrn...
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Overview of the distribution of functional properties in VLPF. P, Principal sulcus; IA, inferior arcuate sulcus; SA, superior arcuate sulcus.
Lateral #PrefrontalCortex is involved in executive functions, but what roles do distinct anatomical subregions play? @clbas.bsky.social &co show that caudal VLPF specializes in visual input processing, while middle areas support context-based behavioral planning @plosbiology.org 🧪 plos.io/4ljEz9W
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Overview of the distribution of functional properties in VLPF. P, Principal sulcus; IA, inferior arcuate sulcus; SA, superior arcuate sulcus.
Lateral #PrefrontalCortex is involved in executive functions, but what roles do distinct anatomical subregions play? @clbas.bsky.social &co show that caudal VLPF specializes in visual input processing, while middle areas support context-based behavioral planning @plosbiology.org 🧪 plos.io/4ljEz9W
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Overview of the distribution of functional properties in VLPF. P, Principal sulcus; IA, inferior arcuate sulcus; SA, superior arcuate sulcus.
Lateral #PrefrontalCortex is involved in executive functions, but what roles do distinct anatomical subregions play? @clbas.bsky.social &co show that caudal VLPF specializes in visual input processing, while middle areas support context-based behavioral planning @plosbiology.org 🧪 plos.io/4ljEz9W
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#CPTSD #PTSD #nervoussystem #neurodivergent #prefrontalcortexdamage #prefrontalcortex #authenticity #masculinity #toxicmasculinity #panic #catatonic #christofascism #fucktrump
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#quotes #books #booksky #excerpts #citations #behave #sapolsky #cheat #cheaters #cheating #brain #neurobiology #prefrontalcortex #pfc
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#mircostressors can be an insidious trap!
Experts Are Sharing Why You Get So "#Mean" When You're Overwhelmed, And Thankfully There's Such A Simple Solution www.yahoo.com/lifestyle/ar...
#overstimulation #prefrontalcortex #technology #deepbreathing #mindfulness #calm
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Top left: Calculation problems (denoted by “§”) began with the presentation of a problem, a brief mask, and an unlimited input duration. Upon giving the correct response, the participant was presented with a new problem. Incorrect responses led to the repetition of the same problem until the correct response was provided. Bottom left: Drill problems (denoted by “♯”) were presented as a combination of two operands and an outcome. In contrast to the calculation problems, in the drill problems, the underlying algorithm to derive the result by calculation was not known. The combination had to be memorized and reproduced after masking. Both presentation time and response input time decreased from one session to the next, overall. Problems were repeated when answered incorrectly. Right: A 3D volume, generated manually in CONN, depicting the four frontoparietal seeds (left dlPFC, right dlPFC, left PPC, right PPC) as well as the right and left frontoparietal connectivity that was used in the functional connectivity analyses.
What role do cortical regions play in #mathematical learning? This study reveals the causal role of dorsolateral #PrefrontalCortex & #frontoparietal network in #math learning using #transcranial neuromodulation in human participants @plosbiology.org 🧪 plos.io/45SyMUI
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Top left: Calculation problems (denoted by “§”) began with the presentation of a problem, a brief mask, and an unlimited input duration. Upon giving the correct response, the participant was presented with a new problem. Incorrect responses led to the repetition of the same problem until the correct response was provided. Bottom left: Drill problems (denoted by “♯”) were presented as a combination of two operands and an outcome. In contrast to the calculation problems, in the drill problems, the underlying algorithm to derive the result by calculation was not known. The combination had to be memorized and reproduced after masking. Both presentation time and response input time decreased from one session to the next, overall. Problems were repeated when answered incorrectly. Right: A 3D volume, generated manually in CONN, depicting the four frontoparietal seeds (left dlPFC, right dlPFC, left PPC, right PPC) as well as the right and left frontoparietal connectivity that was used in the functional connectivity analyses.
What role do cortical regions play in #mathematical learning? This study reveals the causal role of dorsolateral #PrefrontalCortex & #frontoparietal network in #math learning using #transcranial neuromodulation in human participants @plosbiology.org 🧪 plos.io/45SyMUI
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Top left: Calculation problems (denoted by “§”) began with the presentation of a problem, a brief mask, and an unlimited input duration. Upon giving the correct response, the participant was presented with a new problem. Incorrect responses led to the repetition of the same problem until the correct response was provided. Bottom left: Drill problems (denoted by “♯”) were presented as a combination of two operands and an outcome. In contrast to the calculation problems, in the drill problems, the underlying algorithm to derive the result by calculation was not known. The combination had to be memorized and reproduced after masking. Both presentation time and response input time decreased from one session to the next, overall. Problems were repeated when answered incorrectly. Right: A 3D volume, generated manually in CONN, depicting the four frontoparietal seeds (left dlPFC, right dlPFC, left PPC, right PPC) as well as the right and left frontoparietal connectivity that was used in the functional connectivity analyses.
What role do cortical regions play in #mathematical learning?This study reveals the causal role of dorsolateral #PrefrontalCortex & #frontoparietal network in #math learning using #transcranial neuromodulation in human participants @plosbiology.org 🧪 plos.io/45SyMUI
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Is AI changing how we think? Dr. Sarah Baldeo's upcoming skill-building session explores the fascinating intersection of technology and neurodevelopment. Join us Aug 7th, 2:30PM, Room 601! #APADiv1 #PrefrontalCortex #CognitivePsychology #HEART2025 #APA2025
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Recent Discoveries: The Molecular Complexity of Our Brain’s Decision-Maker
#PrefrontalCortex #Neuroscience #BrainResearch #CellularDiversity #Neurobiology #BrainCircuits #Neuromodulation #MentalHealth #Neurogenomics #CognitiveScience
youtube.com/shorts/tIYGc...
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Inside the Mind: Exploring the Brain’s Decision-Making Hub
#BrainScience #Neuroscience #PrefrontalCortex #LimbicSystem #NeuralNetworks #MentalHealth #Cognition #Emotion #BrainConnectivity #Neuroplasticity #StressResilience #SocialBrain #BrainResearch
youtube.com/shorts/xzxdX...
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#quotes #books #booksky #excerpts #citations #determined #sapolsky #cannabis #chronic #prefrontalcortex #dorsolateral #ventromedial #pfc #bloodflow #brain #neurochemistry #neurobiology #thc #weed #ohwell
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Why does your brain find art beautiful?
#Neuroaesthetics is the emerging field that studies how your brain processes beauty, art, and emotional experiences. Spoiler: it’s not all in the eye—it’s in the #prefrontalcortex, reward circuitry, and even motor areas.
#Neuroscience #neuroskyence
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RE neurons respond to pain-like stimuli, emotional changes, and social interaction in SNI mice. Top: Diagram of virus injection (left) and an example image (right) of GCaMP6s expression in the RE. Bottom: Heat maps of changes in GCaMP6s and eYFP signals in the RE in response to von Frey filament (vF) stimulation on the injured hind paw in SNI or sham mice.
The medial #PrefrontalCortex (mPFC) is a key brain area for pain sensation & #ChronicPain. This study shows that modulation of a circuit projecting from nucleus reuniens of the thalamus to mPFC improves neural & behavioral indicators of chronic pain in mice @plosbiology.org 🧪 plos.io/4mpMuEj
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RE neurons respond to pain-like stimuli, emotional changes, and social interaction in SNI mice. Top: Diagram of virus injection (left) and an example image (right) of GCaMP6s expression in the RE. Bottom: Heat maps of changes in GCaMP6s and eYFP signals in the RE in response to von Frey filament (vF) stimulation on the injured hind paw in SNI or sham mice.
The medial #PrefrontalCortex (mPFC) is a key brain area for pain sensation & #ChronicPain. This study shows that modulation of a circuit projecting from nucleus reuniens of the thalamus to mPFC improves neural & behavioral indicators of chronic pain in mice @plosbiology.org 🧪 plos.io/4mpMuEj
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