Rapid elicitation of neutralizing Asn332-glycan-independent antibodies to the V3-glycan epitope of HIV-1 Env in nonhuman primates Nature Immunology - WIN332 is an HIV-1 Env protein designed to elicit a new class of Asn332-glycan-independent antibodies (type II) to the V3-glycan site of Env. WIN332 immunization rapidly induces...

Our #WIN332 work is out! 🥳 rdcu.be/e15ti
In this study, led by Ignacio R. Relano, we report WIN332, the first engineered HIV-1 Env immunogen rationally designed to induce a new class of #TypeII #N332-glycan independent #V3-glycan antibodies. #THANKYOU to our collaborators for a great team effort!

5.0mg / week - Tirzepatide (MounJaro)
HbA1c 59 -> 39 mmol/mol
13% <weight
in 6 months!

Amazing!

#GLP-01ra #GIP #Incretin #mimetics #peptides #exendin-4 #Gila #Monster #Diabetes #TypeII #Obesity #Inflammation #Mounjaro #Tirzepatide #Type2Diabetes #MetabolicHealth
#InsulinResistance