ロシュ、二重GLP-1/GIP作動薬CT-388第2相で48週22.5%減量──肥満で第3相Enith1/2開始へ | STELLANEWS.LIFE STELLANEWS.LIFE（ステラニュース・ライフ）は、科学や技術、医薬品分野における最新の研究成果や発見 | STELLANEWS.LIFE（ステラニュース・ライフ）は、科学や技術、医薬品分野における最新の研究成果や発見

Roche’s dual GLP-1/GIP receptor agonist CT-388 shows 22.5% weight loss in Phase II trial; Phase III Enith1/2 to start

ロシュ、二重GLP-1/GIP作動薬CT-388第2相で48週22.5%減量──肥満で第3相Enith1/2開始へ

stellanews.life/technology/8...

#Obesity #WeightLoss #Roche #ClinicalTrial #GLP1 #GIP

#TheNicotineTest #MECFS #LongCovid #PASC #MECFSResearch #MEResearch #LongCovidResearch #PASCResearch #FundMECFS #FundLongCovid #Vielight #RedLightTherapy #Rutin #HRV #HeartRateVariability #PEM #GIP #PostPrandial #MedicalResearch #PatientLed #PatientLedResearch #FundMedicalResearch

By linking digestion, metabolism, & cardiovascular health, #incretin-based therapies do more than just regulate blood sugar; they help reduce morbidity & mortality & are becoming a core component of modern #diabetes care www.thelancet.com/journals/lan...
#GLP-1 #GIP

#MedSky #EndoSky #CardioSky

5.0mg / week - Tirzepatide (MounJaro)
HbA1c 59 -> 39 mmol/mol
13% <weight
in 6 months!

Amazing!

#GLP-01ra #GIP #Incretin #mimetics #peptides #exendin-4 #Gila #Monster #Diabetes #TypeII #Obesity #Inflammation #Mounjaro #Tirzepatide #Type2Diabetes #MetabolicHealth
#InsulinResistance

#Lilly #obesity #weightloss #PharmaNews #EliLilly #weightlosstherapies #retatrutide #TRIUMPH4trial #GLP1 #GIP #glucagon #subcutaneousinjection #weightreduction #WOMACscale #obesitytherapies #LillyCardiometabolicHealth #kneeosteoarthritis #obstructivesleepapnoea #OSA #Abivax #biotech
zurl.co/pf3xY

« Cette expérience a été marquante : il y a eu un avant et un après. »

Loup Keravel s’est engagé 4 mois sur le terrain dans le cadre de son #GIP www.edhec.edu/fr/news/temo...

#EDHEC #InternationalBBA

Comment Renater veut muscler la sécurité informatique de l’enseignement supérieur - ZDNET Le groupement d’intérêt public va plancher cette année sur la mise en place d’un SOC (Security Operations Center) mutualisé.

Est-ce que quelqu'un•e ici aurait un (ou plus) contact chez @renater-1.bsky.social ?

"Comment Renater veut muscler la sécurité informatique de l’enseignement supérieur"

#Renater #CERT #GIP #CyberSécurité #EnseignementSupérieur ... www.zdnet.fr/actualites/c...

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イーライリリーが開発中の最新ダイエット薬「Retatrutide」（GLP-1/GIP/グルカゴン受容体アゴニスト)が臨床試験で劇効きまくりらしい、痩せすぎて途中で投薬を止める人も出てきている？https://amrit-lab.com/c/AM1282.html
#GIP
#GLP-1

By linking #digestion, #metabolism, and #cardiovascular health, #incretin-based therapies do more than just regulate blood sugar; they help reduce morbidity and mortality and are becoming a core component of modern #diabetes care www.thelancet.com/journals/lan...
#GLP-1 #GIP

#MedSky #EndoSky

As understanding of the gut–bone axis deepens, there is growing interest in leveraging its effects to develop innovative strategies for preventing & treating #bone fragility in the future www.thelancet.com/journals/lan...
#BoneHealth #osteoporosis #fractures
#incretins #GLP-1 #GLP-2 #GIP

#EndoSky

🫀 Now out in the #EHJ: “More than a sidekick: GIP signalling and cardiovascular outcomes” on (tw)incretins, inflammation and CVD.

#GIP mediated BMI lowering is linked to greater reductions in MACE/HF - possibly via anti-inflammatory effects.

Full text: academic.oup.com/eurheartj/ad...

📊#Criteria blinda a #Naturgy al aumentar su paquete al 26%

💶 Criteria escala en Naturgy tras la venta de #GIP y aspira al 29,9%

🫴 Criteria refuerza su poder en Naturgy al comprar un 2% por 477 millones

🗞️temas en las #Portadas de la prensa económica 👇

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現在使用可能なダイエット医薬品リストと開発中の未承認薬。Tirzepatideが最新(2025年12月)https://amrit-lab.com/c/AM1278.html
#Orlistat
#Alli
#GIP
#糖尿病
#脂肪
#GLP-1

Conditions that may be helped by inflacretins: TIER 1: STRONGEST EVIDENCE 1. Type 2 Diabetes 2. Chronic Kidney Disease 3. NAFLD/MASLD (Non-Alcoholic Fatty Liver Disease / Metabolic Dysfunction-Associated Steatotic Liver Disease) 4. NASH (Non-Alcoholic Steatohepatitis) 5. COPD (Chronic Obstructive Pulmonary Disease) TIER 2: STRONG EVIDENCE 6. Sleep Apnoea/EDS (Excessive Daytime Sleepiness) 7. Liver Cirrhosis (compensated) 8. Cognitive Decline 9. Peripheral Neuropathy 10. Rheumatoid Arthritis 11. Hypertension 12. PCOS (Polycystic Ovary Syndrome) 13. IBD (Inflammatory Bowel Disease: Crohn's/UC) 14. Brain/Vascular Inflammation TIER 3: MODERATE EVIDENCE 15. Osteoarthritis 16. Type 1 Diabetes 17. Alcohol Use Disorder TIER 4: PRELIMINARY/EMERGING 18. Nicotine/Tobacco Use 19. DVT Sequelae (Deep Vein Thrombosis Sequelae) 20. Gut Microbiome 21. Other Addictions TIER 5: ANECDOTAL 22. Vascular Eczema 23. Atopic Eczema

Inflacretins, Tirzepatide #GLP-1 / #GIP RA drugs are revolutionary, not just for #diabetes & #obesity.

This article discusses a range of conditions that may be helped, by, inter alia, anti-inflammation effects:
philosophomuse.blogspot.com/2025/12/the-... #addiction #arthritis #MentalHealth #gut 🧪

Conditions that may be helped by inflacretins: TIER 1: STRONGEST EVIDENCE 1. Type 2 Diabetes 2. Chronic Kidney Disease 3. NAFLD/MASLD (Non-Alcoholic Fatty Liver Disease / Metabolic Dysfunction-Associated Steatotic Liver Disease) 4. NASH (Non-Alcoholic Steatohepatitis) 5. COPD (Chronic Obstructive Pulmonary Disease) TIER 2: STRONG EVIDENCE 6. Sleep Apnoea/EDS (Excessive Daytime Sleepiness) 7. Liver Cirrhosis (compensated) 8. Cognitive Decline 9. Peripheral Neuropathy 10. Rheumatoid Arthritis 11. Hypertension 12. PCOS (Polycystic Ovary Syndrome) 13. IBD (Inflammatory Bowel Disease: Crohn's/UC) 14. Brain/Vascular Inflammation TIER 3: MODERATE EVIDENCE 15. Osteoarthritis 16. Type 1 Diabetes 17. Alcohol Use Disorder TIER 4: PRELIMINARY/EMERGING 18. Nicotine/Tobacco Use 19. DVT Sequelae (Deep Vein Thrombosis Sequelae) 20. Gut Microbiome 21. Other Addictions TIER 5: ANECDOTAL 22. Vascular Eczema 23. Atopic Eczema

Inflacretins, Tirzepatide #GLP-1 / #GIP RA drugs are revolutionary, not just #diabetes & #obesity.

This article discusses the range of conditions that may be helped, by, inter alia, anti-inflammation effects: #addiction #arthritis #MentalHealth #gut

philosophomuse.blogspot.com/2025/12/the-...

❌ #GIP rechaza ceder poder en el consejo de #Naturgy 

🚗🔌 Los #consejeros se niegan a adelantar las ayudas al #vehículo #eléctrico 

📱 #BlackRock activa la reordenación de Naturgy tras contactar con #Moncloa y #Caixa 

🗞️temas en las #Portadas de la prensa económica 👇

Antibiotics, and contraceptive drugs are major, recent, radical influences on humanity and human evolution. Inflacretins are the next revolution.

GLP-1 receptor agonists, GIP receptor agonists, Tirzepatide, Mounjaro. #Health #Revolution

philosophomuse.blogspot.com/2025/12/ #GLP-1 #GIP

Weightwatchers files for bankruptcy as Ozempic and Mounjaro surge in popularity The firm is struggling with debt and tough competition from weight-loss drugs.

I didn't notice this at the time. It's a useful reminder that even the most evidently sound business model can succumb to a Black Swan.

www.bbc.co.uk/news/article... #Tirzepatide #Ozempic #GLP-1RA #GIP #obesity #epidemic #BlackSwan

Beyond a singular focus on GLP-1: why we need a new nomenclature now The development of glucagon-like peptide-1 (GLP-1)-based therapies for type 2 diabetes and obesity illustrates a remarkable evolution in scientific understanding and therapeutic innovation.1 As the fi...

Although #GLP-1-based therapy might remain a practical term for the near future, given the central role of GLP-1 in most current molecules and coformulations, there is a clear need for broader, more inclusive terminology thelancet.com/journals/lan...
#incretins #GLP-1 #GIP

#MedSky #EndoSky

Estimating direct tissue effects versus weight loss effects of incretin-based drugs for obesity on various chronic conditions The extent to which newer, incretin-based drugs for obesity improve disease outcomes via weight loss versus the direct effects of these drugs is the subject of intense interest. Although reductions in...

The extent to which newer, #incretin-based drugs for #obesity improve disease outcomes via weight loss versus the direct effects of these drugs is the subject of intense interest www.thelancet.com/journals/lan...
#GLP-1 #GIP

#MedSky #EndoSky

The gut–bone axis: implications of gut hormone-based therapies for bone health Historical trends and future projections of the number of people with overweight and obesity suggest alarming parallel increases in serious and potentially fatal comorbidities, particularly type 2 dia...

Cardiometabolic diseases can have detrimental effects on bone health, leading to fractures, morbidity & mortality, & reduced quality of life. Despite these known relationships, bone health is often underestimated & overlooked in this context www.thelancet.com/journals/lan...
#incretins #GLP-1 #GIP

#Incretins could serve as a crucial evolutionary link between digestion & substrate oxidation, orchestrating substrate allocation to optimise the body's fight or flight response www.thelancet.com/journals/lan...
#GLP-1 #GIP #digestion #metabolism #cardiovascular system

#EndoSky #GastroSky

Olimpiadi Milano-Cortina, il Gip: "Il decreto del governo che blinda la Fondazione è incostituzionale" Il Tribunale di Milano solleva dubbi sul decreto che proteggerebbe la Fondazione dalle indagini per turbativa d'asta

Le #olimpiadi di #milanocortina del #governo, FUN ZIO NE RAN NO!! 😂😂

#governoindegno #incapaci #coni #cio #ioc #sport #olimpiadiinvernali #gip #decreto

www.ilfattoquotidiano.it/2025/11/06/o...

By linking #digestion, #metabolism, & #cardiovascular health, #incretin-based therapies do more than just regulate blood sugar; they help reduce morbidity & mortality & are becoming a core component of modern #diabetes care thelancet.com/journals/lan...
#GLP-1 #GIP

#MedSky #EndoSky #CardioSky

National Medical Products Administration (NMPA) has approved the marketing of Cogriptin Tablets.

📩 info@dengyuemed.com
🔗 dengyuemed.com

#Cogriptin #Beichangping #HisunPharma #Type2Diabetes #DPP4Inhibitor #GLP1 #GIP #NMPA #ChinaPharma #InnovativeDrug #DiabetesTreatment #BloodGlucoseControl

Roche vise à se classer parmi les trois premiers dans les thérapies de perte de poids Principaux renseignements Malgré l’avance de Novo Nordisk et d’Eli Lilly, Roche estime qu’elle dispose d’une forte opportunité sur le marché des médicaments contre l’obésité, qui représente plusieurs milliards de dollars. Son PDG, Thomas Schinecker, a déclaré que ce marché n’en était qu’à ses débuts et qu’il présentait un potentiel énorme en raison de l’augmentation prévue […]

Roche vise à se classer parmi les trois premiers dans les thérapies de perte de poids #Roche #ThérapiesDePerteDePoids #Obésité #GLP1 #GIP

#Incretin hormones—glucagon-like peptide-1 (GLP-1) & glucose-dependent insulinotropic peptide (GIP)—act as a critical link connecting digestion, metabolism, & cardiovascular function, supporting physiological adaptations to nutrient intake thelancet.com/journals/lan...
#GLP-1 #GIP

#MedSky #EndoSky

This is today! I will helping with this event, please stop in for what’s bound to be a great clinical discussion with Dr. Tania Dempsey, Dr. David Kaufman @kaufmanmd.bsky.social and Dr. Irene Ruhoy @ruhoy.bsky.social

#GLP1 #GIP #MECFS #pwME #LongCovid #MedSky #ClinicianRoundtable

Innovative Molecules and Delivery Technologies Enabling the Future of GLP-1-Based Therapies. Read more in #EndocrineReviews: bit.ly/428OSH2
#GLP-1 #GIP #diabetes #obesity @endocrinesociety.bsky.social