#BaCell3D #3DCellBiology #Organoids #InVitroModels #StemCells #3R #Bioengineering #NAMs #Networking #Collaboration #DiseaseModeling #NonAnimalModels #InVitro #Organoid #OoC #OrganOnChip #NewApproachMethodologies #MPS #MicrophysiologicalSystems #Assembloids #Tumoroids #LifeSciences#BiomedicalResearch
#BaCell3D #3DCellBiology #Organoids #InVitroModels #StemCells #3R #Bioengineering #NAMs #Networking #Collaboration #DiseaseModeling #NonAnimalModels #InVitro #Organoid #OoC #OrganOnChip #NewApproachMethodologies #MPS#MicrophysiologicalSystems #Assembloids #Tumoroids #LifeSciences #BiomedicalResearch
So fun to meet lab alumni at conferences and watch how their own labs are thriving!
Really happy to see Jimena Andersen, now faculty at Emory University. When she was at Stanford, Jimena built 3-part #assembloids to study the corticospinal pathway
This is just the beginning: we will need larger cohorts and more advanced cultures that capture cell diversity and interactions, such as #assembloids.
How do we better model cholinergic pathways? By building human brain assembloids. Using CorePlate™ 3D electrodes, the 𝗟𝗶𝘂 𝗟𝗮𝗯 recorded high-res data from hnbM-cortical projections, even transplanting them into mice to establish human-derived pathways. #3Brain #iPSC #HDMEA #Organoids #Assembloids
A recent @npr.org piece by highlights the recent Asilomar meeting we organized on ethical considerations surrounding human stem cell models (#organoids & #assembloids and their transplantation), focusing on emergent questions and the potential to uncover new biology and therapeutics.
Audio below 👇
The @merihuchlab.bsky.social at @mpi-cbg.de developed patient-specific human periportal liver #assembloids.
Read the @nature.com article: https://go.nature.com/4qpL7Xw
Get the breakdown in this week's episode: https://bit.ly/4p3izlj
In our most recent publication in Nature Protocols, we outline detailed methods for performing CRISPR screens in neural #organoids and #assembloids.
The integration of these approaches is becoming increasingly powerful for uncovering human biology and gaining mechanistic insights into disease.
Excellent feature on @aaguirre1980.bsky.social's lab at @michiganstateu.bsky.social!
"Therapeutic drug development for A-fib has struggled because there are no reliable animal models that resemble the disease."
Enter Aguirre's human heart #assembloids ➡️
msutoday.msu.edu/news/2025/12...
#Afib
Applications are pouring in for our international course on neural #assembloids taking place next spring on our beautiful Stanford campus
This is the LAST day to apply! No deadline extensions.
Please share 👇
The inaugural conference on #assembloids and complex cell-cell interactions starting tonight at @cshlnews.bsky.social ! Amazing energy and inspiring opening keynote by Ruslan Medzhitov.
Deadline approaching for participating in the international Stanford Course on Neural Assembloids in spring 2026!
This is an immersive, hands-on course on generating, probing and manipulating stem cell-derived neural #assembloids and #organoids for disease and development modeling.
Perspectives in @ScieMagazine after our Asilomar conferences on neural #organoids and #assembloids
www.science.org/content/arti...
An amazing group of scientists, philosophers, legal scholars, ethicists, policy makers, patient advocates, funders and trainees convened at Asilomar for one of the most stimulating meetings I have had the privilege to organize, focused on the ethics of research with neural #organoids & #assembloids
Graphical abstract from the linked paper showing a cartoon depiction of a pancreatic islet being couple with a blood vessel organoid in co-culture. The two form an assembloid which then forms a pre-vascularized islet.
At @cea.fr, Tubbs et al. combined human 3D blood vessel #organoids with pancreatic islets to form #assembloids.
This vascularized model could help scientists understand why transplanted islets fail so often in #T1D patients.
@cp-cellreports.bsky.social: doi.org/10.1016/j.ce...
Looking forward to a day when I am no longer asked to include animal experiments by reviewers of our research papers. #MedicalResearch #AnimalWelfare #3Rs #DrugRepurposing #Organ-on-a-chip #Tumour-on-a-chip #Tumoroids #Assembloids #Organoids 🧪 www.theguardian.com/science/2025...
Research Roundup: ‘mini brains’ and mindful design From lab-grown "mini brains" to new findings on digital design and political persuasion, University scholars are expanding our narrow ...
#Science #& #Technology #News #assembloids #Graduate #School #of […]
[Original post on stanforddaily.com]
This week: Colin O'Hern and a team in Dr. Aitor Aguirre's lab at Michigan State University made heart-macrophage #assembloids that allow them to model heart #arrhythmias. 🫀
@cp-cellstemcell.bsky.social paper - https://bit.ly/447iUf7
Discussion - https://bit.ly/4qTwoVL
This week, we published in @science.org an article outlining the current ethical and societal implications of research involving human neural #organoids and #assembloids, their transplantation, and highlighted potential next steps.
Applications are now open for the Stanford course on neural #assembloids!
Deadline: December 12
Promotional graphic for a special issue of Disease Models & Mechanisms titled "In Vitro Models of Human Disease to Inform Mechanism and Drug Discovery." The left side of the image contains text announcing the call for papers, edited by Vivian Li, Austin Smith, and Joseph Wu, with a submission deadline of 3 November 2025. The right side features a vibrant, microscopic image of biological tissue or cell structures in vivid pink, blue, and yellow hues, representing the complexity of in vitro disease models. The design combines scientific detail with visual appeal to attract submissions for the issue.
Call for papers: In Vitro Models of Human Disease to Inform Mechanism and Drug Discovery
Deadline approaching: Monday 3 November 2025
journals.biologists.com/dmm/pages/in...
#Biology #Research #Disease #Discovery #Organoids #Tumours #Gastruloids #Assembloids
Our new episode of NeuroSociety Stories is officially live! @sergiuppasca.bsky.social discusses his pioneering work using human stem cells to create neural #organoids and #assembloids for studying brain development and psychiatric disorders.
#neurosociety #neuroscience #neuroethics #brainresearch
Christian Desaintes highlighted @ec.europa.eu support for #organ-on-chip technology.
Lena Smirnova of @jhucaat.bsky.social shared how cortical brain #assembloids are helping us understand #autism risk factors. Check out this 2021 article for more: hub.jhu.edu/magazine/202...
9/16
One week left to register for the 1st conference on assembloids at @cshlnews.bsky.social this December. Spectacular list of speakers (see below) tackling cell-cell interactions across tissues and organs
Two amazing keynotes:
Ruslan M. Medzhitov & Joanna Wysocka
#assembloids #organoids
Great news about our upcoming meeting at Asilomar on the Ethics of Neural #Organoids and #Assembloids Research!
We secured additional support to waive the registration fee for at least 30 participants, which is especially beneficial for trainees
If interested, complete the form at the link below
This was achieved with human midline #assembloids by combining floor plate and spinal cord #organoids from pluripotent stem cells.
Strong interest already in the upcoming Asilomar meeting on the ethical and societal implications of human neural #organoids, #assembloids, and their transplantation.
Just 10 days left to apply—details at the link below.
Participation will be limited.
Apply here before July 20 to join us:
sto.stanfordtickets.org/ethical-and-...
#Organoids #Assembloids #Neuroscience #Bioethics #ScienceAndSociety #Asilomar2026
