At this high resolution, we also caught something new: Using the new #HAK-Actin #UExM probe, we saw that
#Actin accumulates at the furrow base before compartments fully seal ➡️ they're still open at the bottom.

➡️ The #multicellular epithelium-like stage is shorter than we previously proposed.

Think of the smartphone. It didn't appear out of nowhere. First came batteries, chips, camera, mp3, etc developed independently for years. Then came integration into one single entitity! The same happened with animals: unicellular ancestors already had most of the mechanisms to be #multicellular

Sperm's evolutionary origins go back before multicellular animals Analysis of the DNA and proteins of a range of animals has revealed that sperm’s molecular toolkit arose in our single-celled ancestors, perhaps more than a billion years ago

#Sperm 's #evolutionary origins go back before #multicellular #animals

www.newscientist.com/article/2505...

These Enigmatic ‘Fossils’ Could Rewrite the History of Life on Earth Controversial evidence hints that complex life might have emerged hundreds of millions of years earlier than previously thought—and possibly more than once

Complex life may have evolved multiple times on Earth [via @sciam.bsky.social] 🧪🥼🦠🧫🌱🌍

"complex multicellular life appear earlier than previously thought, but it might have done so multiple times"

www.scientificamerican.com/article/comp...

#earth #life #multicellular #organism #evolution

#quotes #books #booksky #excerpts #citations #evolutioninfourdimensions #jablonka #lamb #zeligowski #evolution #epigenetic #genome #dna #molbio #biology #multicellular #social #culture #information #transmission

#ramshornsnail #macro #macrophotography #closeupphotos #pondlife #lichen #fossil #mold #seeds #multicellular #smallworld #biltonart #southyorkshire #lifeforce #macrodesign #magnification #artfulliving #macrophotoartillustration #yorkshireartist #chrisbiltonart #ephemeral

The afternoon of the eighth day of the Konstanz School of Collective Behaviour 2025 (#KSCB2025) is devoted to a #keynote by Naama Brenner on #biophysics of #cells, either in #unicellular or #multicellular #organisms

@cbehav.bsky.social

https://www.exc.uni-konstanz.de/kscb/

Human interpretable grammar encodes multicellular systems biology models to democratize virtual cell laboratories We developed a plain text modeling language—a cell behavior hypothesis grammar—to easily build virtual cell models and connect them to data, helping scientists to unlock the hidden dynamics of tissues...

Paper is in Cell at www.cell.com/cell/fulltex...

@genomeweb.bsky.social
@cp-cell.bsky.social @physicell.bsky.social #mathonco #mathbio #grammar #PhysiCell #multicellular

#busstop #macro #oldmoornaturereserve #macrophotography #closeupphotos #pondlife #lichen #fossil #mold #seeds #multicellular #smallworld #biltonart #southyorkshire #lifeforce #macrodesign #magnification #artfulliving #macrophotoartillustration #yorkshireartist #chrisbiltonart #ephemeral

#macro #macrophotography #closeupphotos #pondlife #lichen #fossil #mold #seeds #multicellular #smallworld #biltonart #southyorkshire #lifeforce #macrodesign #magnification #artfulliving #macrophotoartillustration #yorkshireartist #chrisbiltonart #ephemeral

Leading scientists from around the world will come together to unravel the early steps of #multicellular #evolution and address key questions: 🦠❓🧬

✅ Can we identify universal principles of #multicellularity and/or fundamental differences intrinsic to each lineage?

Vikas Trivedi, @viktri08.bsky.social , interested in understanding how signaling, mechanics, and metabolism are integrated with tissue geometry to generate #multicellular structure

Elizabeth Ostrowski @elizostrow.bsky.social, interested in conflict and cooperation in #multicellular organisms

Tissue-like multicellular development triggered by mechanical compression in archaea The advent of clonal multicellularity is a critical evolutionary milestone, seen often in eukaryotes, rarely in bacteria, and only once in archaea. We show that uniaxial compression induces clonal mul...

Tissue-like #multicellular development triggered by mechanical compression in #archaea
#ArchaeaSky #evolution
doi.org/10.1126/scie...

#frosty #macro #macrophotography #closeupphotos #pondlife #lichen #fossil #mold #seeds #multicellular #smallworld #biltonart #southyorkshire #lifeforce #macrodesign #magnification #artfulliving #macrophotoartillustration #yorkshireartist #chrisbiltonart #ephemeral

Many #Insightful points by #SuzanneSimard, 1 about #LynnMargulis, an evolutionary #biologist with the theory of #endosymbiosis, which is that #evolution is a #coevolutionary #process the coming #together of different #organisms, that led to the development of #multicellular organisms like #people. 🙏

Left: Experimental strains were constructed by inserting GFP, myohemerythrin, or myoglobin at the HO locus in the yeast chromosome. Top right: Box and whisker plot of oxygen diffusion depth using the mitochondrial MitoLoc reporter in snowflake yeast clusters expressing oxygen-binding proteins or wild-type controls under oxygen limitation. Bottom right: Representative fluorescence micrographs of MitoLoc showing increased depth of oxygen penetration (white colocalization between GFP in cyan and RFP in magenta) in clusters expressing myoglobin (right) compared to a wild-type control (left) under low oxygen.

How did early #multicellular organisms exploit rising O2 levels? By expressing animal O2-binding proteins in snowflake yeast, @wcratcliff.bsky.social &co show that myoglobins & myohemerythrins circumvent anatomical limits to O2 diffusion in multicellular organisms 🧪 @plosbiology.org plos.io/3Ejt16N

Left: Experimental strains were constructed by inserting GFP, myohemerythrin, or myoglobin at the HO locus in the yeast chromosome. Top right: Box and whisker plot of oxygen diffusion depth using the mitochondrial MitoLoc reporter in snowflake yeast clusters expressing oxygen-binding proteins or wild-type controls under oxygen limitation. Bottom right: Representative fluorescence micrographs of MitoLoc showing increased depth of oxygen penetration (white colocalization between GFP in cyan and RFP in magenta) in clusters expressing myoglobin (right) compared to a wild-type control (left) under low oxygen.

How did early #multicellular organisms exploit rising O2 levels? By expressing animal O2-binding proteins in snowflake yeast, @wcratcliff.bsky.social &co show that myoglobins & myohemerythrins circumvent anatomical limits to O2 diffusion in multicellular organisms 🧪 @plosbiology.org plos.io/3Ejt16N

Left: Experimental strains were constructed by inserting GFP, myohemerythrin, or myoglobin at the HO locus in the yeast chromosome. Top right: Box and whisker plot of oxygen diffusion depth using the mitochondrial MitoLoc reporter in snowflake yeast clusters expressing oxygen-binding proteins or wild-type controls under oxygen limitation. Bottom right: Representative fluorescence micrographs of MitoLoc showing increased depth of oxygen penetration (white colocalization between GFP in cyan and RFP in magenta) in clusters expressing myoglobin (right) compared to a wild-type control (left) under low oxygen.

How did early #multicellular organisms exploit rising O2 levels? By expressing animal O2-binding proteins in snowflake yeast, @wcratcliff.bsky.social &co show that myoglobins & myohemerythrins circumvent anatomical limits to O2 diffusion in multicellular organisms 🧪 @plosbiology.org plos.io/3Ejt16N

#macro #macrophotography #closeupphotos #pondlife #lichen #fossil #mold #seeds #multicellular #smallworld #biltonart #southyorkshire #lifeforce #macrodesign #magnification #artfulliving #macrophotoartillustration #yorkshireartist #chrisbiltonart #ephemeral

We are all in this together #allinthistogether #ink #watercolor #multicellular

#ice #frost #macro #macrophotography #closeupphotos #pondlife #lichen #fossil #mold #seeds #multicellular #smallworld #biltonart #southyorkshire #lifeforce #macrodesign #magnification #artfulliving #macrophotoartillustration #yorkshireartist #chrisbiltonart #ephemeral

#icecrystals #snow #freezing #macro #macrophotography #closeupphotos #pondlife #lichen #fossil #mold #seeds #multicellular #smallworld #biltonart #southyorkshire #lifeforce #macrodesign #magnification #artfulliving #macrophotoartillustration #yorkshireartist #chrisbiltonart #ephemeral

I just want to #welcome all the new members with a beautiful multinucleated #Ichthyosporean just before undergoing #cellularization to form a transient #multicellular stage.
Imaged using #Expansion #Microscopy ( #UExM )

Species: Sphaeroforma arctica
Blue: Nuclei
Magenta: Tubulin

Thrilled to share the final and improved (thanks & shoutout to Maaike and Iker) version of #Phylogenomic insights into the first #multicellular #streptophyte now online @currentbiology.bsky.social #plantsci #charophytes #evolution www.cell.com/current-biol...

Thrilled to share the final and improved (thanks & shoutout to @MaaikeBier @IkerIrisarri ) version of #Phylogenomic insights into the first #multicellular #streptophyte now online @CurrentBiology | @watertoland #plantsci #charophytes #evolution...

Zygnema #genomes are here!! This has been a great collaborative effort with many friends!! #Chromosome-level genomes of #multicellular algal sisters to land #plants illuminate signaling network #evolution || #plantsci #algae @ERC_Research @watertoland ...

Pr Andy Knoll (Harvard) gave a seminar on the history of #multicellular #eukaryotes and its link to Earth’s physical history, using physiology as the bridge.
Watch the seminar on youtube: https://youtu.be/qTNAbghNcj0
#geobiology #EarthHistory @BImpmc @IMPMC_Lab @DEEMteam_Orsay

Pr Andy Knoll (Harvard) gave a seminar on the history of #multicellular #eukaryotes and its link to Earth’s physical history, using physiology as the bridge.
Watch the seminar on youtube: https://youtu.be/qTNAbghNcj0
#geobiology #EarthHistory @BImpmc @IMPMC_Lab @DEEMteam_Orsay

#multicellular #flwx