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Starving the Tumor: Can Ketogenic Diets Break Cancer’s Lactate Shield and Reactivate NK Cells? Your Science-based Guide to Wellness, Diet and Lifestyle Medicine

Starving the Tumor: Can Ketogenic Diets Break Cancer’s Lactate Shield and Reactivate NK Cells? Cancer is no longer just a battle of chemotherapy vs. tumors. Modern oncology is uncovering a hidden...

#diet #and #cancer #keto #diet #metabolic-immune #cancer #NK #cells

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Starving the Tumor: Can Ketogenic Diets Break Cancer’s Lactate Shield and Reactivate NK Cells? Your Science-based Guide to Wellness, Diet and Lifestyle Medicine

Starving the Tumor: Can Ketogenic Diets Break Cancer’s Lactate Shield and Reactivate NK Cells? Cancer is no longer just a battle of chemotherapy vs. tumors. Modern oncology is uncovering a hidden...

#diet #and #cancer #keto #diet #metabolic-immune #cancer #NK #cells

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Abstract:  Liquid biopsy is revolutionizing cancer management, with circulating tumor cells (CTCs), offering a transformative approach to screening, diagnosis, and treatment monitoring. However, existing CTC isolation methods relying on antigen expression or physical properties lack robustness, are operator-dependent, and suffer from automation challenges, leading to inconsistent and time-intensive analyses. A universal, unbiased methodology for CTC detection across tumor types is critically needed. Here, we present the first proof-of-concept study demonstrating the use of Fourier transform infrared (FT-IR) microspectroscopy to study cytospun blood samples coupled with a random forest (RF) classifier, for the detection of a single CTC in the blood of a lung cancer patient as confirmed via immunohistochemistry. Notably, our method utilizes glass coverslips as substrates, routinely employed in pathology departments, enabling seamless integration with histopathological analyses (e.g., staining, immunohistochemistry). Using FT-IR spectral data from in vitro growing lung cancer cells as a training model, we achieved precise CTC identification based on biochemical composition, specifically within the fingerprint region (1800 cm–1 to 1350 cm–1). This study introduces FT-IR microspectroscopy as a novel, label-free approach for CTCs detection in liquid biopsies, with the potential to redefine cancer diagnostics. By enhancing precision and accessibility in CTC identification, the clinical implementation of this methodology may represent a significant advancement in personalized oncology, offering a clinically viable tool for real-time cancer monitoring and improved patient stratification.

Abstract: Liquid biopsy is revolutionizing cancer management, with circulating tumor cells (CTCs), offering a transformative approach to screening, diagnosis, and treatment monitoring. However, existing CTC isolation methods relying on antigen expression or physical properties lack robustness, are operator-dependent, and suffer from automation challenges, leading to inconsistent and time-intensive analyses. A universal, unbiased methodology for CTC detection across tumor types is critically needed. Here, we present the first proof-of-concept study demonstrating the use of Fourier transform infrared (FT-IR) microspectroscopy to study cytospun blood samples coupled with a random forest (RF) classifier, for the detection of a single CTC in the blood of a lung cancer patient as confirmed via immunohistochemistry. Notably, our method utilizes glass coverslips as substrates, routinely employed in pathology departments, enabling seamless integration with histopathological analyses (e.g., staining, immunohistochemistry). Using FT-IR spectral data from in vitro growing lung cancer cells as a training model, we achieved precise CTC identification based on biochemical composition, specifically within the fingerprint region (1800 cm–1 to 1350 cm–1). This study introduces FT-IR microspectroscopy as a novel, label-free approach for CTCs detection in liquid biopsies, with the potential to redefine cancer diagnostics. By enhancing precision and accessibility in CTC identification, the clinical implementation of this methodology may represent a significant advancement in personalized oncology, offering a clinically viable tool for real-time cancer monitoring and improved patient stratification.

New from Applied Spectroscopy!
Fourier Transform Infrared Microspectroscopy as a Liquid Biopsy Tool to Detect Single Circulating Tumour Cells in the Blood of a Lung Cancer Patient
More: https://doi.org/10.1177/00037028251390565
#SAS #Spectroscopy #FTIR #Microspectroscopy #circulating #tumour #cells

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An improved way to detach cells from culture surfaces A new strategy for detaching cells from culture surfaces could transform large-scale biomanufacturing by enabling automated and contamination-conscious workflows for cell therapies, tissue engineering...

An improved way to detach #cells from #culture surfaces

Anne Wilson | Department of Mechanical Engineering
news.mit.edu/2025/improve...
MIT News 11/18/2025

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#Faster #cancerscreening? New #AI system offers a better way to #detect #abnormal #cells

AI-powered 3D scanning system Whole-Slide Edge Tomography creates digital cell models to detect cancer. It IDs abnormalities with near-expert accuracy in minutes scitechupdates.com/f...

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Thank you very much for joining my #plenary #lecture during the spring meeting of the German Physical Society of the Condensed Matter Section (#SKM) #DPGDD26 in #Dresden about: On the sunny side - #polymer-based #organic #solar #cells - it was great to have such big audience

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This computer runs on living human brain cells | REUTERS
This computer runs on living human brain cells | REUTERS YouTube video by Reuters

This #computer runs on living #human #brain #cells

www.youtube.com/watch?v=3KeC...
YouTube, Reuters 3/6/2025

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NK Cell Immunometabolism: How Tumor Metabolism Disables Natural Killer Cells (2026 Guide) Your Science-based Guide to Wellness, Diet and Lifestyle Medicine

NK immunometabolism 101 NK-metabolic therapy (sometimes called NK immunometabolism ) is an emerging concept in cancer immunotherapy that focuses on optimizing the metabolism of Natural Killer Cells...

#cancer #immunotherapy #NK #cells

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NK Cell Immunometabolism: How Tumor Metabolism Disables Natural Killer Cells (2026 Guide) Your Science-based Guide to Wellness, Diet and Lifestyle Medicine

NK immunometabolism 101 NK-metabolic therapy (sometimes called NK immunometabolism ) is an emerging concept in cancer immunotherapy that focuses on optimizing the metabolism of Natural Killer Cells...

#cancer #immunotherapy #NK #cells

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NK Cell Immunometabolism: How Tumor Metabolism Disables Natural Killer Cells (2026 Guide) Your Science-based Guide to Wellness, Diet and Lifestyle Medicine

NK immunometabolism 101 NK-metabolic therapy (sometimes called NK immunometabolism ) is an emerging concept in cancer immunotherapy that focuses on optimizing the metabolism of Natural Killer Cells...

#cancer #immunotherapy #NK #cells

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Pathogenic virus infects and structurally reorganizes human cells, finds new study Orthohantaviruses, such as the Puumala virus, are widespread in Europe, causing flu-like illnesses and severe kidney damage in those infected. It is increasingly considered a zoonotic threat.…

#Pathogenic #virus #infects and structurally reorganizes human #cells ...

| #pathogens | #Orthohantaviruses | #Puumala | #infections | #Illness | Via @sciencex.bsky.social

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Natural Killer Cells 101: What You Need to Know (2026) Your Science-based Guide to Wellness, Diet and Lifestyle Medicine

Natural Killer Cells 101: What You Need to Know (2026) Natural killer (NK) cells, a specific type of white blood cell, are an important component of your innate immune system. Your immune system co...

#101 #cancer #CAR-NK #immunotherapy #NK #cells #stem #cells

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Which organ removes old or damaged red blood cells? A) Kidney B) Liver C) Spleen D) Pancreas #redblo Which organ removes old or damaged red blood cells? A) Kidney B) Liver C) Spleen D) Pancreas #redblo

Which organ removes old or damaged red blood cells?
A) Kidney
B) Liver
C) Spleen
D) Pancreas
#redbloodcells #organs #hematology #cells ... Continue to: www.facebook.com/113009240922...

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So everybody heard about #cells and how they make up the body, right? And that cells take up and release molecules (it's how they eat and communicate...), and how they are made up of organelles that have membranes.

Now check this out: cells nip off bits of themselves, sometimes even with organelles

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Plant Cell Structure Could Hold Key to Cancer Therapies and Improved Crops Can the bend of a banana give us insight into cancer? What does the shape of a rice grain have to do with infertility? The proteins that give plants their shape and structure are also involved in huma...

🌱 From UC Davis: Scientists mapped the augmin complex that organizes plant cell skeletons, offering clues for cancer research and new ways to shape crop growth. (Jawdat Al-Bassam, Bo Liu)

▶️ www.ucdavis.edu/news/plant-c...

#PlantScience #PlantBiology #Cells

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Iran may be activating sleeper cells outside the country, alert says The U.S. has intercepted encrypted communications believed to have originated in Iran that may serve as “an operational trigger” for “sleeper assets."

#Iran may be activating #sleeper #cells outside the country, alert says.

The encrypted transmission was intercepted by the U.S.

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Scientists just found an unknown force that helps the brain wire itself This insight may also help researchers better understand how other organs develop and could eventually inspire new medical strategies.

Scientists just found an unknown force that helps the brain wire itself This insight may also help researchers better understand how other organs develop and could eventually inspire new medical st...

#Neuroscience #Brain #Cells #Neurons

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Scientists just found an unknown force that helps the brain wire itself This insight may also help researchers better understand how other organs develop and could eventually inspire new medical strategies.

Scientists just found an unknown force that helps the brain wire itself This insight may also help researchers better understand how other organs develop and could eventually inspire new medical st...

#Neuroscience #Brain #Cells #Neurons

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Lukas V. Spanier et al in #Solar RRL (@AdvPortfolio): The role of #halogen-free #solvents on the #stability of PTQ-2F:BTP-4F-based #organic #solar #cells

Solar RRL 10, e202500819 (2026)

doi.org/10.1002/solr...

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Living cells float gracefully in a blue-tinted microscopic landscape, showcasing the fundamental processes of life itself. Multiple cellular structures display their delicate membranes and internal components, while others are caught in different stages of division. The soft, ethereal lighting creates a dreamy atmosphere, transforming this scientific view into a captivating glimpse of biology in action. Each cell appears to dance in its own space, demonstrating the dynamic nature of microscopic life.

Living cells float gracefully in a blue-tinted microscopic landscape, showcasing the fundamental processes of life itself. Multiple cellular structures display their delicate membranes and internal components, while others are caught in different stages of division. The soft, ethereal lighting creates a dreamy atmosphere, transforming this scientific view into a captivating glimpse of biology in action. Each cell appears to dance in its own space, demonstrating the dynamic nature of microscopic life.

🔬 Did you know #cholesterol influences membrane molecules in ways previously thought impossible, making them stiffer? See how in Chakraborty et al's dataset and article at doi.org/10.25422/azu..., doi.org/10.7294/V8W6... and doi.org/10.1073/pnas.... Image: Stockcake. #OpenData #OpenScience #Cells

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Polymers that crawl like worms: How materials can develop direction without being told where to go Researchers at the University of Vienna have uncovered a surprising phenomenon: polymer chains with segments that simply fluctuate at different intensities can spontaneously develop directional, persistent motion when densely packed – even though nothing in the system points them in any particular direction. This "entropic tug of war," driven by fundamental physical constraints, could help explain how DNA organizes and moves inside living cells, and may lead to new materials. The study was currently published in Physical Review X.

5-Mar-2026
#Polymers that crawl like worms: How #materials can develop direction without being told where to go
New findings can help to better understand #DNA dynamics in living #cells

https://www.eurekalert.org/news-releases/1118843

#science #nanoworld

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Scientists finally explain statin muscle pain Statins are a cornerstone of heart health, but muscle pain and weakness cause many patients to quit taking them. Scientists have now identified the precise molecular trigger behind these side…

" #Researchers have discovered why #statins can cause #MusclePain: the drugs force open a key #muscle channel, flooding #cells with calcium. The finding could help scientists design next-generation statins.": buff.ly/erbgV0D

via sciencedaily
#cholesterol #medication #statin #medicine

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Assembly of Arundinella anomala genome to facilitate single-cell resolved functional and developmental characterization of C4 distinctive cells - Nature Plants The genome of Arundinella anomala, a C4 grass with variant Kranz anatomy and interveinal distinctive cells, is sequenced and annotated, followed by single-cell transcriptomes for comparative analyses ...

Assembly of #Arundinella anomala #genome to facilitate #single-cell resolved functional and #developmental characterization of #C4 distinctive #cells

www.nature.com/articles/s41...

#PlantScience #StressBiology @natureportfolio.nature.com @natplants.nature.com @alliancegenome.bsky.social

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Your Cells Can ‘Remember’—Meaning Your Entire Body Could Be Conscious, Some Researchers Suggest A recent study suggests that memories aren’t just stored in the brain, raising important questions about cognition.

Your #Cells Can ‘Remember’—Meaning Your Entire #Body Could Be #Conscious, Some Researchers Suggest

www.popularmechanics.com/science/a705...

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Immunotherapy to Treat Cancer (2026): Types, Benefits, Risks, and Latest Breakthroughs Your Science-based Guide to Wellness, Diet and Lifestyle Medicine

Immunotherapy to Treat Cancer (2026): Types, Benefits, Risks, and Latest Breakthroughs Cancer immunotherapy represents a major paradigm shift in oncology — mobilizing a patient's own immune s...

#101 #cancer #immunotherapy #NK #cells #pharma #stem #cells

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Exosomes are natural messengers involved in that process — and they’re an exciting area of ongoing research.
At the Miley Clinic, our physicians can help you explore whether this conversation is worth having as part of your care.

📌 Schedule a consultation: 9412174440

#Exosomes #cells #florida

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A Long #History of Almost Nothing : Medium

How Can #Infinity Come in Many Sizes? : Quanta Mag

Ultra-sensitive #CAR-T #Cells eliminate hard-to-treat #Tumours in #Mice : Nature

Latest #KnowledgeLinks

knowledgezone.co.in/resources/bo...

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5 Best Metroidvania Series of All Time Metroidvanias have become one of the most exciting genres in gaming, but their rise did not happen overnight. While they have always thrived on core pillars l...

#Gaming #Castlevania #(Gaming) #Dead #Cells #Hollow #Knight […]

[Original post on comicbook.com]

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Ancient Microbes Fused Into Earth’s First Complex Cells. Scientists Learned What Made It Possible. Around 1.7 billion years ago, eukaryotes—the building blocks of complex life—first appeared on Earth, and now scientists have solved a longstanding riddle about their origin.

#Ancient #Microbes Fused Into #Earth’ s First Complex #Cells. #Scientists Just Learned What Made It Possible.

www.popularmechanics.com/science/anim...

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Novartis settles with Henrietta Lacks' estate over use of her 'stolen' cells to advance medicine Novartis has settled a lawsuit by the estate of Henrietta Lacks that alleged the pharmaceutical giant unjustly profited off her cells, which were taken from her tumor without her knowledge in 1951 and...

#Novartis settles with #HenriettaLacks’ estate over use of her ‘stolen’ #cells to advance #medicine

apnews.com/article/henr...

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