@missionmsa.bsky.social had an incredible Path to a Cure 5k event in Miami last weekend. Thank you to everyone that came out to support us as we raised awareness and funds to support those living with multiple system atrophy. #MSA #multiplesystematrophy

Learn more about our work at missionmsa.org.

Locus coeruleus degeneration is associated with orthostatic hypotension in Parkinson’s disease and multiple system atrophy - Clinical Autonomic Research Purpose We compared locus coeruleus (LC) structural integrity, as measured by neuromelanin-sensitive magnetic resonance imaging (NM-MRI), between patients with Parkinson’s disease (PD) and those with ...

Coeurleophiles and autonomic fanatics, rejoice! I bring you a paper combining both.
Here, we show that orthostatic hypotension must accounted for if attempting to utilize locus coeruleus integrity (with NM-MRI) in the DDx of #Parkinson's and #MultipleSystemAtrophy.
link.springer.com/article/10.1...

Excited to be at @movedisorder.bsky.social Annual Meeting. Always great to meet, network, and continue to build strong partnerships for the betterment of the #MSA community!

#multiplesystematrophy

Brain Support Network and Stanford's Movement Disorders Center co-hosted a Multiple System Atrophy Symposium on Saturday, May 4, 2024.

See our playlist of videos from the symposium:
www.youtube.com/playlist?lis...

#MSA #multiplesystematrophy

Speech Treatment for People with Cerebellar Multiple System Atrophy (MSA-C): A Pilot Randomised Controlled Trial of Two Approaches - The Cerebellum Speech problems are an early feature of Multiple System Atrophy (MSA). They can lead to social withdrawal and have significant impact on people’s quality of life. There is a considerable lack of clini...

Congratulations to PSH researchers Prof Anja Lowit and Dr Kaiyue Xing and the team for producing the first #RCT showing that speech and language therapy can be beneficial for people with #MultipleSystemAtrophy #MSA !! Read here ⬇️

tinyurl.com/z84fz27a

@msatrust.bsky.social #bskySPEECHIES

Sage Journals: Discover world-class research Subscription and open access journals from Sage, the world's leading independent academic publisher.

Cerebellar #multiplesystematrophy #MSA & cognition.
Huge number of patients (210).
- 24.8% of patients had cognitive impairment on neuropsych tests of language, memory and processing speed
- *NO* association with OH or HTN
- ⬆️risk w/age, MRI hot-cross bun sign

journals.sagepub.com/doi/full/10....

I had a wonderful time at @ean.org Annual Congress. Content, speakers, and opportunity to engage and network was tremendous.

#EAN2025 #multiplesystematrophy #MSA

June is Men's Health Awareness Month, which is the perfect opportunity to bring attention to the millions of men who are living with dysautonomia. 🫶

Follow DSN for resources and support.

#dysautonomia #MensHealthMonth #MultipleSystemAtrophy #PureAutonomicFailure #MSA #PAF

I love this graph. Which endpoints or successes should be measured and considered through the life experiences of patients.

#raredisease #clinicaltrials #multiplesystematrophy #MSA

We’re glad to be at @nordrare.bsky.social #RareDiseaseScientificSymposium. What a needed event to learn from other #raredisease orgs, clinicians, scientists, patients, and industry. At @missionmsa.bsky.social we’re excited about accelerating therapies and understanding for #multiplesystematrophy

Research Discovery: Neurodegeneration in multiple system atrophy (MSA) is caused by toxic protein clumps that penetrate the nuclei of neurons and cause the death of those cells.

Diseases affected: Multiple System Atrophy (MSA)

Key findings: Oligodendrocytes are not the primary cause of MSA, as previously thought.

What's next? By identifying neurons as the primary victims of α-synuclein toxicity, researchers can now develop treatments that protect neurons from invasive protein aggregates or enhance the cells’ ability to clear them out.

A breakthrough in #MultipleSystemAtrophy (MSA) research: Dr. Victor Dieriks and his team in NZ have identified that the cause of this neurodegenerative disorder is toxic α-synuclein protein aggregates that invade neuron nuclei.

buff.ly/YKLxq6O

Correlations between Dysphagia Severity Scale Scores and Clinical Indices in Individuals with Multiple System Atrophy.

https://pubmed.ncbi.nlm.nih.gov/40129375/

#neurodegeneration #ALS #multiplesystematrophy

🧠 New PubMed Article Alert!

Differential diagnosis of multiple system atrophy with predominant parkinsonism and Parkinson's disease using neural networks (part II).

https://pubmed.ncbi.nlm.nih.gov/39893881/

#neurodegeneration #Parkinsons #multiplesystematrophy

I'm so glad to have found you here on BlueSky. My husband has MSA-C and MSA-P, we are in Australia and sadly there is little known about this condition amongst Oz medicos and support groups are few and far between. I look forward to reading about your work and updates.
#MSA
#MultipleSystemAtrophy

Mark your calendars to gather, connect, and engage in discussions surrounding the latest scientific discoveries and best care practices related to multiple system atrophy #MSA #multiplesystematrophy

we messed up Rab5 - it's on the outside, rather than inside, of endosomes lol. we're fixing that! but it might be useful for ppl anyway, so we're releasing it now.

#polyamine
#polyamines
#spermidine
#spermine
#Cancer
#Parkinsons
#multiplesystematrophy

Pathology of #multiplesystematrophy (MSA). Here is your quiz. When I teach resident courses on this topic folks know this is a #synucleinopathy however they forget the glial cytoplasmic inclusions. Can you spot them in Dennis Dickson's @MayoClinic beautiful pic? @OGdukeneurosurg

Read the full article at fixel.ufhealth.org/2022/05/23/tracking-the-...

#Parkinsons #PD #PSP #ProgressiveSupranuclearPalsy #MultipleSystemAtrophy #MSA #MRI #BrainScience #Neurology #Neuroscience

#alphasynuclein aggregates in Parkinson’s and MSA are potential drug targets. Researchers @mpi_bpc and @DZNE_DE have now investigated aggregates from patient tissue for the first time – with surprising findings. https://www.mpibpc.mpg.de/17136602/pr_1929
#Parkinson #MultipleSystemAtrophy

#alphasynuclein aggregates in Parkinson’s and MSA are potential drug targets. Researchers @mpi_bpc and @DZNE_DE have now investigated aggregates from patient tissue for the first time – with surprising findings. https://www.mpibpc.mpg.de/17136602/pr_1929
#Parkinson #MultipleSystemAtrophy

#alphasynuclein aggregates in Parkinson’s and MSA are potential drug targets. Researchers @mpi_bpc and @DZNE_DE have now investigated aggregates from patient tissue for the first time – with surprising findings. https://www.mpibpc.mpg.de/17136602/pr_1929
#Parkinson #MultipleSystemAtrophy

#alphasynuclein aggregates in Parkinson’s and MSA are potential drug targets. Researchers @mpi_bpc and @DZNE_DE have now investigated aggregates from patient tissue for the first time – with surprising findings. https://www.mpibpc.mpg.de/17136602/pr_1929
#Parkinson #MultipleSystemAtrophy

#alphasynuclein aggregates in Parkinson’s and MSA are potential drug targets. Researchers @mpi_bpc and @DZNE_DE have now investigated aggregates from patient tissue for the first time – with surprising findings. https://www.mpibpc.mpg.de/17136602/pr_1929
#Parkinson #MultipleSystemAtrophy

#alphasynuclein aggregates in Parkinson’s and MSA are potential drug targets. Researchers @mpi_bpc and @DZNE_DE have now investigated aggregates from patient tissue for the first time – with surprising findings. https://www.mpibpc.mpg.de/17136602/pr_1929
#Parkinson #MultipleSystemAtrophy