🎃Our October issue's out!
Cover: mechanoresponsive #microtubules

👉🏼Reviews: #CellularStress ; #NuclearPoreComplex & #mechanobiology
🔬 #StemCells #senescence #cancer #EndoplasmicReticulum #phagocytosis #pyroptosis #autophagy #PhaseSeparation #AMPK #chromatin & more!
www.nature.com/ncb/volumes/...

📝 Available online - the Review "The nuclear export receptor CRM1/XPO1 and its diverse cargoes" from Ralph Kehlenbach and @yuhminchook.bsky.social.

#CRM1 #Exportin1 #NuclearTransport #NuclearPoreComplex #RNAExport

Read it here: authors.elsevier.com/sd/article/S...

📝 Online now - the Review "The intersection of viral #mimicry and nuclear entry" from David Jacques et al.

#Viruses #NuclearPoreComplex #NuclearImport #NuclearTransportReceptors

Read it here: authors.elsevier.com/a/1lZ0o3S6Gf...

Reconstitution of lamin assembly on nuclear pore complex-containing membranes
Pedersen, R. T., Reyes, A. V. et al.
Paper
Details
#LaminReconstitution #NuclearPoreComplex #CellBiologyResearch

spotLights Ep 14: preLights in conversation with Matteo Allegretti YouTube video by The Company of Biologists

I met @matteoall.bsky.social, as well as discussing the impact of preprints, he explained his research on the nuclear pore complex and why sperm cells do not need as much transport in/out of the nucleus. #Cryotomography #NuclearPoreComplex (4/5) www.youtube.com/watch?v=42th...

Revolutionizing HIV treatment: unveiling the new frontiers of HIV capsid research Revolutionizing HIV treatment with lenacapavir: first capsid inhibitor overcoming drug resistance, long-acting efficacy, 100% prophylaxis success.

Revolutionizing HIV treatment with lenacapavir: first capsid inhibitor overcoming drug resistance, long-acting efficacy, 100% prophylaxis success.

amm-journal.org/index.php/20...

#HIV1CapsidProtein #Lenacapavir #NuclearPoreComplex #NuclearTranslocation #DrugDesign #HIVtreatment

Nuclear pore complex protein RANBP2 and related SUMOylation in solid malignancies

This review explores in detail the significance of #RANBP2, a lesser-known SUMO E3 ligase & #NuclearPoreComplex protein, across various malignancies and highlights its potential as a prospective therapeutic target for #cancer treatment. #SUMOylation #Epigenetics #medsky

#OpenAccess: buff.ly/J4BZsEe

#HIV cracks the #nuclearporecomplex during passage😲
👉abberior #3DSTED was used to show that HIV capsids accumulate at nuclear pores of the host cell
👉abberior #STED was used to determine the exact localization of HIV capsid relative to the nuclear pore
😎

#superresolution #STEDmicroscopy #virology

A #dSTORM image of the #NuclearPoreComplex in Cos7 cells with a zoomed in image of a single pore.

Happy New Year from ONI! We wish you a great 2025, full of scientific discoveries and breakthroughs! We cannot wait to see where will your curiosity take you this year.

Here is a #dSTORM image of the #NuclearPoreComplex in Cos7 cells.

#CuriousMinds #SuperResolution #Nanoimager