Illumina introduces Billion Cell Atlas to accelerate AI and drug discovery

One billion cell atlas project from #Illumina and collaborators AstraZeneca, Eli Lily and Merck
#singlecell #perturbseq #PIPseq

www.illumina.com/company/news...

Genome-scale perturb-seq in primary human CD4+ T cells maps context-specific regulators of T cell programs and human immune traits Gene regulatory networks encode the fundamental logic of cellular functions, but systematic network mapping remains challenging, especially in cell states relevant to human biology and disease. Here, ...

This is pretty awesome. #perturbseq

www.biorxiv.org/content/10.6...

🧠 Arc Workshop at the upcoming scverse conference 2025 🧠

Processing and Modeling Large-Scale Single-Cell Perturbation Data with Machine Learning
🧵

@arcinstitute.org

#scverse2025 #PerturbSeq #MachineLearning #SingleCell #CRISPR #GenomicScreening #VirtualCells

LLM‑Powered HypoGeneAgent Improves Cluster Resolution for Perturb‑seq

HypoGeneAgent, an LLM tool, generates GO hypotheses with a score for cluster granularity; on K562 CRISPRi Perturb‑seq dataset it outperformed silhouette scores. Read more: getnews.me/llm-powered-hypogeneagen... #hypogeneagent #perturbseq

🧠 Arc Workshop at the upcoming scverse conference 2025 🧠

Processing and Modeling Large-Scale Single-Cell Perturbation Data with Machine Learning
🧵

@arcinstitute.org

#scverse2025 #PerturbSeq #MachineLearning #SingleCell #CRISPR #GenomicScreening #VirtualCells

🚨 New preprint from the #EricAndWendySchmidtCenter! 🚨
"MORPH Predicts the Single-Cell Outcome of Genetic Perturbations Across Conditions and Data Modalities"

www.biorxiv.org/content/10.1...

@broadinstitute.org #SingleCell #PerturbSeq #OpticalPooledScreen #AIinBiology #ScienceNews #CompBio

33/ We'd love to get feedback from the community #neuroinflammation #multiplesclerosis #Alzheimer #microglia #iPSC #CRISPR #Perturbseq #GWAS #epigenome #neurodegeneration

Spatially Resolved in vivo CRISPR Screen Sequencing via Perturb-DBiT Perturb-seq enabled the profiling of transcriptional effects of genetic perturbations in single cells but lacks the ability to examine the impact on tissue environments. We present Perturb-DBiT for si...

Spatially Resolved in vivo CRISPR Screen Sequencing via Perturb-DBiT #spatial #perturbseq
www.biorxiv.org/content/10.1...