#SingleCellTranscriptomics of #bonemarrow in #Type2Diabetes reveals impaired #cytokinesignaling, reduced #osteoclast activity, and diminished Cd36+ precursor differentiation, driven by dysregulated AP-1 transcription factor activity.

#OpenAccess: doi.org/10.1016/j.ge...

Single-Cell Omics Analysis Reveals Critical Cell Subtypes and their Functional Attributes in Myocardial Ischemia-Reperfusion Injury Announcing a new article publication for BIO Integration journal. Cardiac cell death and myocardial fibrosis after ischemia-reperfusion (I/R) injury are the primary causes of impaired cardiac function...

This study uses #SingleCellTranscriptomics to identify C0 Atcayos+ cardiomyocytes that interact with #fibroblasts via Bmp6 and Fgf1 signaling after #IschemiaReperfusion, uncovering pathways that could reduce #fibrosis and help preserve #cardiac function.

Read: bio-integration.org/single-cell-...

T-cell immunoglobulin and mucin domain-containing protein 3–mediated immunomodulation in myeloid cells and keratinocytes in the development of severe acne - Molecular Biomedicine Acne vulgaris is a common chronic inflammatory skin disorder with significant clinical and societal impacts. Severe acne (SA), in particular, causes scarring, disfigurement, and psychosocial distress....

#Research
T-cell immunoglobulin and mucin domain-containing protein 3–mediated immunomodulation in myeloid cells and keratinocytes in the development of severe acne doi.org/10.1186/s435...

#SevereAcne #TIM3 #SingleCellTranscriptomics #Macrophages #Keratinocytes

The challenges of single cell transcriptomics on difficult human tissue: the placenta Demand for the application of single cell transcriptomics on difficult tissues, processed and stored in disparate conditions, has led to the development of various single cell modalities. We focus on ...

Interested in applying #singlecelltranscriptomics to a difficult tissue? Please check out this #new preprint from our group and led by Dorian Xenakis. Important read for experimental design and analysis!

www.biorxiv.org/content/10.1...

Explore how spatial and #singlecelltranscriptomics reveal tissue architecture and cellular interactions. Watch our on-demand webinar for insights into cellular complexity and gene expression. https://bit.ly/4jc0yyo

#SpatialTranscriptomics #Genomics #CellBiology #Innovation

Microbial profiling and single-cell transcriptomics reveal probiotic mechanisms of coral thermal resilience
C.-H., C.-Y. et al.
Paper
Details
#MicrobialProfiling #CoralResilience #SingleCellTranscriptomics

Missing data in single-cell transcriptomes reveals transcriptional shifts
Basu, S., Chen, R. et al.
Paper
Details
#SingleCellTranscriptomics #TranscriptionalShifts #MissingDataAnalysis

Explore how spatial and single-cell transcriptomics reveal tissue architecture and cellular interactions. Watch our on-demand webinar for insights into cellular complexity and gene expression. bit.ly/4jc0yyo #SingleCellTranscriptomics #SpatialTranscriptomics #Genomics #CellBiology #Innovation

Day 4 of the #LongTREC #SummerSchool has started! This morning, @eamonmc.bsky.social and Juan Francisco Cervilla Martínez will cover Single-cell transcriptomics with #LongReads

#LongReadsTranscriptomics #SingleCellTranscriptomics

Fundamental Limitations of Foundation Models in Single-Cell Transcriptomics
Atti, S., Subramaniam, S.
Paper
Details
#FoundationModels #SingleCellTranscriptomics #LimitationsInSCt

Decoding Cellular Stress States for Toxicology Using Single-Cell Transcriptomics
Camiolo, S., Chambers, B. A. et al.
Paper
Details
#SingleCellTranscriptomics #ToxicologyResearch #CellularStressStates

Explore how spatial and single-cell transcriptomics reveal tissue architecture and cellular interactions. Watch our on-demand webinar for insights into cellular complexity and gene expression.

bit.ly/4jc0yyo

#SingleCellTranscriptomics #SpatialTranscriptomics #Genomics #CellBiology #Innovation

New collab out with Jennifer Zhang & Amy Petty of @dukemedschool.bsky.social #Dermatology Department! #scRNAseq performed by #DukeMGC

'Insights into #Keratinocyte and Immunologic Landscape in #Cutaneous #Graft-Versus-Host Disease through #SingleCellTranscriptomics' 🧬💻

doi.org/10.1016/j.xj...

Garlic clove virus study reveals meristem defense & glutathione role! 🧬🛡️ #SingleCellTranscriptomics #GarlicVirusImmunity @OxfordJournals
Details: doi.org/10.1093/hr/u...