Join us at Neuro Winter Summit 2026 in Hokkaido, Japan, March 24–28 at Rusutsu Resort.
Visit Booth #2 to meet Benjamin Compans & Michel Biocco and discuss how #superresolution imaging can advance #neuroscience research, from #synapses to subcellular dynamics.
#Microscopy
Secure Your Seat! Only a few weeks to go until the #SYNAPSES Conference on Sustainability Citizenship for teachers and school leaders in Greece 🇬🇷
👉 Be part of a growing community shaping the future of sustainable education: conference.synapses-academies.eu #schoolleaders #schoolheads
Join our Memory Decoding Journal Club: “Engram cell connectivity as a mechanism for information encoding and memory function” (Ortega-de San Luis et al.) w/ Ariel Zeleznikow-Johnston — Tue, Mar 3, 3pm PT. meet.google.com/udr-jcdc-vkp
#memory #engram #neuroscience #synapses
Join our Memory Decoding Journal Club: “Engram cell connectivity as a mechanism for information encoding and memory function” (Ortega-de San Luis et al.) w/ Ariel Zeleznikow-Johnston — Tue, Mar 3, 3pm PT. meet.google.com/udr-jcdc-vkp
#memory #engram #neuroscience #synapses
What do ER-peroxisomes contacts do? These are a key hub for ether lipid and plasmalogen biosynthesis. Plasmalogens stabilize curved membrane surfaces and are highly enriched at #synapses and in synaptic vesicles. 9/13
New research maps the slow cascade from brief tau toxicity to lasting synaptic dysfunction, offering a more dynamic view of neurodegeneration.
longevity.technology/news/tau-exp...
#longevity #neuroscience #alzheimersresearch #braindegeneration #synapses #agingbrain
repost @adrianisaac.art on IG
#Synapses Sound design 🔊😎 by the radical @rzn_music #generativeart #curves #3dart #mathart #digitalart #blender3d #abstract #codeart
Roles of circular RNAs targeted to #synapses: Narrative review of potential mechanisms and biomarkers
Li et al. review the roles of #CircularRNAs in synaptic function and their potential as #biomarkers for #neurodegenerativediseases.
www.sciencedirect.com/science/arti...
By leveraging in situ cryo-ET, Tian et al. obtained high-resolution, #3D views of the native #ultrastructure of intact hippocampal #synapses. See here: doi.org/10.1007/s122...
A new #fluorescent sensor, iGluSnFR3, reveals #glutamate release at #synapses in real time 🧠✨
Developed by teams from the Allen Institute, HHMI, and UC San Diego, it makes the brain’s fastest signals visible, enabling deeper insight into how #neurons communicate across networks.
#Gemini3
"What made me think that #ErikaKirk is a Zionists' golem?"
From the let's explore the world to-get-her through #LLM #tokens, artificial #synapses #department.
Go on, #observe.
gemini.google.com/share/050346...
Slitrk1 and Slitrk2 proteins are widely expressed in various layers of hippocampal CA1 and DG but exhibit distinct enriched expression patterns. (A) Schematic of immunohistochemical analysis strategy used to analyze the protein expression patterns of Slitrk1 and Slitrk2 in the hippocampal subfields of adult mice. Representative images showing Slitrk1 protein distribution in coronal brain sections from adult male mice. Scale bar, 100 µm (applies to all images). (B–I) Representative images (B, F for Slitrk1 and C, G for Slitrk2) and quantification of mean intensity distributions for Slitrk1 (D, H) and Slitrk2 (E, I) across CA1 and DG layers. Data are presented as means ± SEMs (n = 6 mice/group). Scale bars, 50 µm (applies to all images). Abbreviations: SO, stratum oriens; SR, stratum radiatum; SP, stratum pyramidale; SLM, stratum lacunosum-moleculare; GCL, granule cell layer; ML, molecular layer.
Slitrk1 & Slitrk2 are structurally & biochemically similar, so what role do they each play in #synapses? This study shows that each acts in distinct #hippocampal subfields & via different binding partners. Relevance to Slitrk2's association with #schizophrenia @plosbiology.org 🧪 plos.io/4qibtuo
Slitrk1 and Slitrk2 proteins are widely expressed in various layers of hippocampal CA1 and DG but exhibit distinct enriched expression patterns. (A) Schematic of immunohistochemical analysis strategy used to analyze the protein expression patterns of Slitrk1 and Slitrk2 in the hippocampal subfields of adult mice. Representative images showing Slitrk1 protein distribution in coronal brain sections from adult male mice. Scale bar, 100 µm (applies to all images). (B–I) Representative images (B, F for Slitrk1 and C, G for Slitrk2) and quantification of mean intensity distributions for Slitrk1 (D, H) and Slitrk2 (E, I) across CA1 and DG layers. Data are presented as means ± SEMs (n = 6 mice/group). Scale bars, 50 µm (applies to all images). Abbreviations: SO, stratum oriens; SR, stratum radiatum; SP, stratum pyramidale; SLM, stratum lacunosum-moleculare; GCL, granule cell layer; ML, molecular layer.
Slitrk1 & Slitrk2 are structurally & biochemically similar, so what role do they each play in #synapses? This study shows that each acts in distinct #hippocampal subfields & via different binding partners. Relevance to Slitrk2's association with #schizophrenia @plosbiology.org 🧪 plos.io/4qibtuo
Slitrk1 and Slitrk2 proteins are widely expressed in various layers of hippocampal CA1 and DG but exhibit distinct enriched expression patterns. (A) Schematic of immunohistochemical analysis strategy used to analyze the protein expression patterns of Slitrk1 and Slitrk2 in the hippocampal subfields of adult mice. Representative images showing Slitrk1 protein distribution in coronal brain sections from adult male mice. Scale bar, 100 µm (applies to all images). (B–I) Representative images (B, F for Slitrk1 and C, G for Slitrk2) and quantification of mean intensity distributions for Slitrk1 (D, H) and Slitrk2 (E, I) across CA1 and DG layers. Data are presented as means ± SEMs (n = 6 mice/group). Scale bars, 50 µm (applies to all images). Abbreviations: SO, stratum oriens; SR, stratum radiatum; SP, stratum pyramidale; SLM, stratum lacunosum-moleculare; GCL, granule cell layer; ML, molecular layer.
Slitrk1 & Slitrk2 are structurally & biochemically similar, so what role do they each play in #synapses? This study shows that each acts in distinct #hippocampal subfields & via different binding partners. Relevance to Slitrk2's association with #schizophrenia @plosbiology.org 🧪 plos.io/4qibtuo
A breathtaking glimpse into the #brain at work: NeuroCure researchers & colleagues @janakroll.bsky.social captured #synapses in action - revealing how #neurotransmitters are released in milliseconds 🧠 Published in NatureCommunications @Charite @mdc-berlin.bsky.social
www.nature.com/articles/s41...
Expression of RIN1 in spinal cord SOM+ interneurons. Immunohistochemistry for RIN1 (red) and PSD-95 (green) in SOM+ interneurons (blue) labelled by intraspinal injection of AAV2/9-DIO-EGFP in SOM-Cre mice. Arrows indicate colocalization. Scale bar, 10 µm.
Modulating #NMDAR subunit composition is important for synaptic function, but how is this controlled? This study shows that RIN1 differentially regulates localization of GluN2B & GluN2A subunits at spinal #synapses, with insights into development & neuropathic pain @plosbiology.org 🧪 plos.io/447TTRf
Expression of RIN1 in spinal cord SOM+ interneurons. Immunohistochemistry for RIN1 (red) and PSD-95 (green) in SOM+ interneurons (blue) labelled by intraspinal injection of AAV2/9-DIO-EGFP in SOM-Cre mice. Arrows indicate colocalization. Scale bar, 10 µm.
Modulating #NMDAR subunit composition is important for synaptic function, but how is this controlled? This study shows that RIN1 differentially regulates localization of GluN2B & GluN2A subunits at spinal #synapses, with insights into development & neuropathic pain @plosbiology.org 🧪 plos.io/447TTRf
Expression of RIN1 in spinal cord SOM+ interneurons. Immunohistochemistry for RIN1 (red) and PSD-95 (green) in SOM+ interneurons (blue) labelled by intraspinal injection of AAV2/9-DIO-EGFP in SOM-Cre mice. Arrows indicate colocalization. Scale bar, 10 µm.
Modulating #NMDAR subunit composition is important for synaptic function, but how is this controlled? This study shows that RIN1 differentially regulates localization of GluN2B & GluN2A subunits at spinal #synapses, with insights into development & neuropathic pain @plosbiology.org 🧪 plos.io/447TTRf
📅 5–9 Jan 2026
⏰ Deadline: 19 Dec 2025
🔗 Program: lnkd.in/duQcc9sq
🔗 Register: lnkd.in/d6ptmtFM
@ucoimbra.bsky.social
#Neuroscience #Synapses #PDBEB #idpIN
🧪🔍 New insight into #cell communication: Researchers discovered a ring-shaped “cap” that controls electrical #synapses. This tiny structure may help explain how cells fine-tune their signals. 🔗 aktuelles.uni-frankfurt.de/english/new-....
In 🐁, some #pericyte #PrimaryCilia penetrate #astrocytic #endfeet and reach the #neuropil - sometimes near #synapses! Could these #cilia act as sensory “antennae” 📡for #NeurovascularCoupling?
🧪🧵5/8
En tant que phénotype et sans surprise, l' #intelligence est influencée par près de 200 gènes qui jouent entre autres sur la #neurogénèse, la production de myéline et des #synapses. Mais cette capacité mentale est aussi environnementale.
via @theconversation.com
theconversation.com/lintelligenc...
For a meme this is OK...
But spines reach out and retract dynamically. It seems unlikely that these are associated with a presynaptic terminal. Some fraction have no postsynaptic elements (checked in vivo). Also some #synapses are onto the dendritic shaft.
www.cell.com/neuron/fullt...
On Sunday, don't miss the Presidential Special Lecture by the one and only @tspiresjones.bsky.social ! #SfN25 #SfN2025 #Alzheimer's #synapses #glia
In this opening #Editorial, Samuel M. Young Jr. and Lu-Yang Wang introduce "The giant impact of #synapses on brain function and disease" special issue 📖 📜
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
#Research by Cristina Román-Vendrell of mblscience.bsky.social et al. observed that acute introduction of monomeric or multimeric α-synuclein induces distinct impacts on synaptic vesicle trafficking at lamprey giant #synapses 🧠 🧪
📜 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
Flyer for SYNAPSES Symposium (Thursday October 23rd at Room 116 at 100 College Street) with talks by Ann Rose Bright, PhD at 9:00am, Peter Hasenhuetl, PhD at 10:00am, Minhyeok Chang, PhD at 11:15am, and Zhenggang Zhu, PhD at 12:15pm. Registration QR code at top right.
"TOMORROW @yaleneuro.bsky.social @kavliatyale.bsky.social Yale present #SYNAPSES, our senior postdoc symposium! 🙌
Hear from four incredible researchers 👩🔬🥼 as they share their latest discoveries and insights! 🗣️
You won't want to miss it! 🗓️"
