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#vasculardysfunction
Posts tagged #vasculardysfunction on Bluesky
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
@sigtrans-sttt.bsky.social
1 month ago
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This #STTT study provides mechanistic insights into how arginase1 regulates mitochondrial cristae remodeling and #mtDNA release, triggering the cGAS-STING pathway and #PANoptosis during ischemic/hypoxic #VascularDysfunction.

#OpenAccess: doi.org/10.1038/s413...

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Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
@sigtrans-sttt.bsky.social
5 months ago
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Arg1 mediates mitochondrial cristae remodeling, #mtDNA release, and activation of the cGAS-STING pathway, resulting in the #PANoptosis of VSMCs during ischemic/hypoxic injury-induced #VascularDysfunction. #medsky

#STTT #OpenAccess: doi.org/10.1038/s413...

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Blood Journals Portfolio
Blood Journals Portfolio
@bloodjournals.hematology.org
11 months ago
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Chronic thrombus in veins has greater MMP9 activity than more acute thrombus in arteries, with MMP9 appearing to be derived from macrophages trapped in thrombus. buff.ly/tHkatpL #hemesky #vasculardysfunction

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