Function | New Article Alert! 🚨This review examines how excessive alcohol use can damage peripheral nerves and increase pain sensitivity, and proposes #MitochondrialDysfunction as a key mechanism linking chronic pain and #AlcoholUseDisorder. Read https://ow.ly/EKff50Yrvc9

Assessing Generative AI Chatbots for Alcohol Misuse Support: A Longitudinal Simulation Study Large language model–based chatbots are increasingly used for behavioral health support. Few studies have rigorously evaluated their advice on alcohol misuse. We evaluated seven publicly available ...

" #Chatbots were perceived to vary widely in their ability to support individuals with alcohol misuse. Although responses were generally strong in empathy, response quality has potential for improvement." ai.nejm.org/doi/10.1056/...
#MedSky #PublicHealth #PatientExperience #GenAI #AlcoholUseDisorder

Faster, decision-ready metrics for alcohol use disorder studies – BioSymetrics/Lunai Bioworks

In collaboration with Dr. Calum MacRae's lab at Harvard Medical School and Brigham and Women's Hospital, BioSymetrics (a @lunaibioworks.com company) is supporting an AUD project to optimize phenotyping across the addiction cycle. #AlcoholUseDisorder #DrugDiscovery #ComputerVision

Lower IQ & cognitive performance link to higher alcohol use disorder risk, but educational attainment & national context can amplify or reduce this vulnerability.

🧬 Genes contribute ~50% of risk, but structural conditions shape outcomes.

buff.ly/eA43xdC

#AlcoholUseDisorder #Genetics #MentalHealth

What Is a High Functioning Alcoholic? Signs, Risks, and Help - The Trinity Wellness Group What is a high functioning alcoholic? Learn common signs, hidden risks, and when to seek support before it gets worse.

You don’t have to hit rock bottom to seek help. High-functioning alcoholism can look successful on the outside while causing harm within. Early support can change everything.

#AlcoholUseDisorder

Learn more👇

Excited to share our newest #SingleCell work on human #AlcoholUseDisorder in #Amygdala out in @natcomms.nature.com
Paper: tinyurl.com/3xh54ath
Data: zenodo.org/records/1765...
Code: github.com/mjgirgenti/A...

#Neuroscience #AlcoholUseDisorder #SingleCell #Epigenomics #GeneRegulation

Lunai Bioworks Expands NIH-Funded AI Program into Commercial Alcohol Use Disorder Drug Discovery

Lunai Bioworks is expanding an NIH-funded AI program into a commercial Alcohol Use Disorder (AUD) drug discovery initiative, following a key milestone in our NIH STTR-supported work. #AlcoholUseDisorder #DrugDiscovery #AIinHealthcare

Modulatory effects of GLT-1 enhancer, MC-100093, on glutamate uptake and associated signaling pathways in female and male alcohol preferring rats exposed to ethanol Significance Statement This study reports the preclinical testing of novel drug, MC-100093, for the attenuation of ethanol intake. The pharmacological aspe

🧠 Targeting glutamate uptake pathways
By restoring glutamate homeostasis in a reward-relevant brain region, MC-100093 highlights a target-focused, mechanism-driven strategy for AUD pharmacotherapy.

👉 Read more on: doi.org/10.1093/ijnp...
#DrugDiscovery #Pharmacology #CNSDrugs #AlcoholUseDisorder

Aspirin and N-acetylcysteine co-administration markedly inhibit chronic ethanol intake and block relapse binge drinking: Role of neuroinflammation-oxidative stress self-perpetuation - PubMed Chronic alcohol intake leads to neuroinflammation and cell injury, proposed to result in alterations that perpetuate alcohol intake and cued relapse. Studies show that brain oxidative stress is consistently associated with alcohol-induced neuroinflammation, and literature implies that oxidative stre …

article published in 2019
link to full text:
repositorio.udd.cl/server/api/c...

~
Female only study ('Adult female rats, Wistar-derived, bred for over 90 generations as alcohol consumers').

#AlcoholUseDisorder

Alcohol use in women creates more health risks than it does in men. Find out why when you listen to the full Alcohol Use Disorder episode at Avaaz Health, wherever you get your podcasts.
#alcoholusedisorder #MedicalPodcast #southasianheath
@drngrewal.bsky.social @mangoe93.bsky.social

Happy New Year! This week we're throwing it back to our 2023 podcast episode on alcohol use disorder. Listen to the full episode at Avaaz Health wherever you get your podcasts.

#alcoholusedisorder #MedicalPodcast #southasianheath
@drngrewal.bsky.social @mangoe93.bsky.social

Two US maps, side by side, show SUDTFs offering MAUD. Map A, labeled '2017,' and Map B, labeled '2023,' use blue to indicate 'No' and grey to indicate 'Yes'. The 2023 map shows a higher number of areas with SUDTFs offering MAUD than the 2017 map.

Availability of medications for #AlcoholUseDisorder is lowest in rural and socioeconomically disadvantaged counties, highlighting persistent treatment gaps.

ja.ma/49ReXP0

Is it possible that a #GLP1 after #MetabolicSurgery offers a 2-for-1 benefit, lowering the risk of #AlcoholUseDisorder as well as weight regain? New data in @jamanetworkopen.com hint at this.
conscienhealth.org/2025/12/enco...

Recent LSD use linked to lower odds of alcohol use disorder #Science #HealthandMedicine #MentalHealth #LSDResearch #AlcoholUseDisorder #MentalHealthAwareness

Alcohol use disorder triggers a distinct immune response linked to neurodegeneration #Science #HealthandMedicine #Neurology #AlcoholUseDisorder #Neurodegeneration #ImmuneResponse

GLP-1 Therapeutics and Their Emerging Role in Alcohol and Substance Use Disorders: An Endocrinology Primer Abstract. Alcohol and other substance use disorders (ASUDs) are complex, multifaceted, but treatable medical conditions with widespread medical, psychologi

GLP-1 Therapeutics and Their Emerging Role in Alcohol and Substance Use Disorders: An Endocrinology Primer. Read more in #JES: bit.ly/4acTEYP #alcoholusedisorder #addiction #GLP-1 @endocrinesociety.bsky.social

Save the Date: December 2nd, 2025

Join us for Module 1: Intro to Alcohol Use & AUD
A 1-hour overview of DSM-5 criteria, key risks, stigma, and the real social/economic impact. Learn the facts behind alcohol-related harm.

#RSA #AlcoholUseDisorder #AlcoholAwareness #ReduceHarm

#TLM25: Jon E. Potter, a patient advocate for those living with #LiverDisease as a result of alcohol use disorder, speaking Nov. 7 at the @aasldnews.bsky.social 2025 meeting in Washington, D.C.

Image & quote taken by Senior Correspondent, Larry Luxner.

#PatientAdvocacy #AlcoholUseDisorder

New Research from PRC: Effects of Impaired Control and Pharmacological Criteria for Lifetime Alcohol Use Disorder on Relationships between Drinking and Problems

prev.org
#alcoholusedisorder #AUD #alcoholawareness #alcoholharms #alcohol #SubstanceUseAwareness #substanceabuseawareness

Cannabidiol shows no immediate effect on brain or behavior in young people with alcohol use disorder, study finds #Science #HealthandMedicine #MentalHealth #Cannabidiol #AlcoholUseDisorder #MentalHealthResearch

Read more: doi.org/10.1093/ijnp...

#AlcoholUseDisorder #Hippocampus #Neurogenesis #AddictionResearch

A recent study finds starting #Naltrexone at hospital discharge reduces heavy drinking days in patients with #AUD. Both oral and injectable forms seemed to be effective, allowing treatment to be tailored to patient needs.

🔗 Read more: buff.ly/a68GCTo

#AddictionMedicine #AlcoholUseDisorder #MedEd

First up:

Researchers found that female and male patients with #AlcoholUseDisorder shared similar demographics, symptoms, and number of visits to the emergency room. However, hospital re-visits and mortality rates were higher among men.
Sex-specific screening could help better support patients.

Dopamine-boosting drug enhances self-control and reduces drinking in people with alcohol use disorder #Science #HealthandMedicine #MentalHealth #Dopamine #AlcoholUseDisorder #SelfControl

Chess-Based Cognitive Remediation Training - A Candidate Add-On-Treatment for Alcohol Use Disorder?
Gerhardt, S., Kiefer, F. et al.
Paper
Details
#ChessTherapy #AlcoholUseDisorder #CognitiveRemediation

Individuals with alcohol use disorder have much higher concentration of glutathione in certain brain areas #Science #HealthandMedicine #MentalHealth #AlcoholUseDisorder #Neuroscience

Ashamed of #NIAAA for holding up these training grants across the country (it's not just ours). I thought training scientists to study #alcoholusedisorder and develop treatments and meaningful interventions is something the government actually wanted to fund? #postdoc

Clearmind Medicine Expands Clinical Trial for Alcohol Use Disorder with New Israeli Site Clearmind Medicine Inc., (Nasdaq: CMND) a biotech company focused on psychedelic-based therapies, has announced the expansion of its Phase I/IIa clinical trial

#CMND is expanding its groundbreaking clinical trial for Alcohol Use Disorder (AUD) with the addition of Tel Aviv Sourasky Medical Center as a new research site.
#ClearmindCMND #AlcoholUseDisorder
prismmarketview.com/clearmind-me...

In our latest episode, we spoke with Dr. Faiza Khan Khattak, CTO of Monark Health, about Responsible AI, Interpretable LLMs & building ethical AI for healthcare.
#WiAIR #WomenInAI #AlcoholUseDisorder #MentalHealth #ResponsibleAI

Grant didn’t expect to be the subject of a private HR meeting. That conversation changed his life.

Stigma kept him quiet and kept others unaware of how common substance use is at work.

It’s time to build recovery-ready workplaces.
👉 Read Grant’s story: bit.ly/3YSaQwo #aud #sud #alcoholusedisorder