Congratulations to our National Cancer Institute scholarship awardees: Anamica Das, Natalia Pinello Gini, Eleni Liapi, Benedetta Ricci, Fu Xu & Kohki Yamada.

The future of RNA biology and epitranscriptomics looks bright! ✨

#RNA #RNAModifications #Epitranscriptomics #CancerResearch

💢The @epiageing-lab.bsky.social is offering an international #PhD contract to investigate in #Epitranscriptomics, #earlydevelopment and #cancer, funded by #MaríaDeMaeztu excellence program at @cimususc.bsky.social
📆Deadline: 19/04/2026
📌More info: cimus.usc.gal/es/training/...

Pan-modification profiling facilitates a cross-evolutionary dissection of the thermoregulated ribosomal epitranscriptome Pan-Mod-seq enables systematic, multi-modification mapping of rRNA across life. Applying it to diverse organisms reveals that hyperthermophiles dynamically install stabilizing modifications to support...

Very happy to share our latest article at the
@SchragaSchwartz
Lab on RNA modifications, specifically on 16 rRNA modifications, their dynamics, across the tree of life. #Epitranscriptomics #RNAmods

You can check it out using the following link www.cell.com/cell/abstrac...

YTHDF1 regulates chemotherapy response by suppressing NOTCH1-induced stemness in colorectal cancer.
RNA regulation intersects with treatment resistance.
doi.org/10.1038/s413...
#ColorectalCancer #YTHDF1 #NOTCH1 #CancerStemness #ChemotherapyResponse #Epitranscriptomics

🧬 RNA Modifications Newsletter – February 2026 ⛸️ issue #8

⛸️🧬 February RNA Modifications Newsletter

From CRISPR-triggered tRNA tail cleavage to temperature-responsive rRNA modifications, ribosome QC, and pathway-specific rRNA modification during biogenesis.
#RNAmods #Epitranscriptomics #Ribosome #Translation #tRNA #rRNA

Altogether, more than 130 different ONT experiments analysed, including IVTs, cell lines, and tissues. SWARM is open source, operates without a control sample & works with both ONT chemistries: github.com/comprna/SWARM
#RNA #Epitranscriptomics #Nanopore
6/6

Excited to share our latest preprint: "SWARM: A Single-Molecule Workflow for High-Precision Profiling of RNA Modifications" www.biorxiv.org/content/10.6...
Led by Stefan Prodic #RNA #Epitranscriptomics #Nanopore 1/6

🌟 EURECA is live on Bluesky!
We’re launching the European Epitranscriptomics of Cancer Academy, a new MSCA‑DN network exploring RNA modifications in cancer.
🔬 Training 14 PhDs
🤝 Partnering across Europe
🌐 eureca-dn.com
💙 Let’s decode cancer at the RNA level.
#CancerResearch #RNA #Epitranscriptomics

The updated MODOMICS #database expands #RNAmodification annotations with transcriptome wide data, enhanced structural descriptors and interactive tools for the 20th anniversary. #Epitranscriptomics
📄 https://doi.org/10.1093/nar/gkaf1284 
👤 EVBC members: Filip Stefaniak, Janusz Bujnicki

SWARM: A Single-Molecule Workflow for High-Precision Profiling of RNA Modifications Nanopore direct RNA sequencing promises to decode the epitranscriptome by detecting multiple modifications on individual RNA molecules, but its potential for biological discovery is hampered by high f...

SWARM: A Single-Molecule Workflow for High-Precision Profiling of RNA Modifications
#RNAmods #epitranscriptomics #nanopore
github.com/comprna/SWARM
www.biorxiv.org/content/10.6...

🎉Our new paper out: the 6th update of MODOMICS, marking 20 years of our RNA 🧬modification database. Largest update so far, including >48,000 human RNAs with modification sites, collaboration with Sci-ModoM & Human RNome Project. NAR 2025 doi: 10.1093/nar/gkaf1284
#RNA #Epitranscriptomics #Databases

New research from our department: Andrew Shafik, Peng Jin and colleagues map patterns of m6a (methyladenosine) RNA modification in human brain across the lifespan @natneuro.nature.com #neuroscience #epitranscriptomics www.nature.com/articles/s41...

PhD opportunity for Chinese Nationals interested in applying for a fellowship from the Chinese Scholarship council #CSC: Come join our lab to study #epitranscriptomics in yeast and bacteria using #Nanopore sequencing #ONT! Deadline: Dec. 15, 2025

🔥 What happens when the epigenetic and epitranscriptomic worlds collide? 🔗 bit.ly/3XBVavZ
A new Cell study uncovers a surprising connection between METTL3–METTL14 and DNMT1.
_______
#Epigenetics #Epitranscriptomics #DNA #StemCellResearch #GeneRegulation #ActiveMotif #LifeScience

📰 🎃 RNA Modifications Newsletter – October 31st - November 1st, 2025 Issue #5

🎃 Trick or transcript?
Bacteria rewire their RNA world under stress & infection. tRNA mods as dual-function sensors, phage tRNA slashers, hibernating ribosomes & haunted translation hubs.
🧬🧪 Full November 1st issue → #RNAmod #Epitranscriptomics #HalloweenScience
#rnasky #microsky

We’re on the road again next week! 🚀
Catch Immagina at:

🔬 EMBL Epitranscriptome | Oct 28–30 | Heidelberg — Meet Lutz at our booth!
🔬 RNA Horizons 2025 | Oct 29–31 | Palermo — Don’t miss Max’s talk on the 29th! 🎤

See you there! 👋
#RNA #Ribosome #Epitranscriptomics

#RNA #Neuroscience #Epitranscriptomics #GeneExpression #MolecularBiology

#Cancer
#RNAsky
#RNAMods
#epitranscriptomics
#RNACancer
@ciccancer.bsky.social
@usaloficial.bsky.social
@csic.es
@contracancerinv.bsky.social

#Cancer
#RNAsky
#RNAMods
#epitranscriptomics
#RNACancer
@ciccancer.bsky.social
@usaloficial.bsky.social
@csic.es
@contracancerinv.bsky.social

📝 Online now - the Review "Mapping rRNA, tRNA, and mRNA modifications in ribosomes at high resolution" from Lukasz Koziej and Sebastian Glatt.

#RNAmodifications #epitranscriptomics #TranslationRegulation #CodonBias #TherapeuticTargeting

Read it here: authors.elsevier.com/a/1lnYa3S6Gf...

✨ RNA Modifications Newsletter – September 15, 2025 issue #3

🧬 Fresh RNA modifications newsletter out now: viral tRNA hijacking, hidden rRNA mods, dynamic Ψ, antibiotic resistance & more.

👉 open.substack.com/pub/rnamodif...

#RNAsky #Epitranscriptomics #microsky #ribosome

Epigenetics: History, Molecules, and Diseases Buy Epigenetics: History, Molecules, and Diseases on Amazon.com ✓ FREE SHIPPING on qualified orders

This issue may *possibly* have been raised somewhere in the 400+ pages of my forthcoming book:

www.amazon.com/Epigenetics-...

When everything is epi-, nothing is epi-. Scientists are typically literate, just say what you mean and no confusion need arise.

#epigenetics #epitranscriptomics

Spotlight on @evamarianovoa.bsky.social PI at @crg.eu Barcelona, leading the Epitranscriptomics & RNA Dynamics lab. Don’t miss her talk “Decoding the epitranscriptome at single-molecule resolution: towards clinical applications” at our RNA Symposium!🔬 zurl.co/mrhKq

#rna #epitranscriptomics #omics

The crosstalk of m6A-modified RNA with DNA damage repair. #m6A #Epitranscriptomics #DNArepair @cp-trendsbiochem.bsky.social
www.cell.com/trends/bioch...

tRNA modification profiling reveals epitranscriptome regulatory networks in Pseudomonas aeruginosa Abstract. Transfer RNA (tRNA) modifications have emerged as critical post-transcriptional regulators of gene expression affecting diverse biological and di

⭐NAR Breakthrough!⭐
🧬 Sun et al. just dropped a high-throughput method to track all #tRNA #modifications across cells & tissues using #massspec.
Read the full article here: doi.org/10.1093/nar/...
#NARBreakthrough #RNA #tRNA #epitranscriptomics #systemsbiology #therapeuticdiscovery.

The final session of day 3 of our #LongTREC summer school. Leda Katopodi talks all things epitranscriptomics. She covers detection of RNA modifications, differential analysis, biological implications and more!

#Epitranscriptomics #RNAModifications #TransferRNA #tRNA

Next up in our LongTREC video series is Leda Katopodi!

Leda is doing exciting research at @crg.eu, working with
@evamarianovoa.bsky.social
to explore the role of epitranscriptomic modifications of #tRNAs in cancer and beyond!

#CancerResearch #tRNAs #RNAMods #Epitranscriptomics

Single-molecule direct RNA sequencing reveals the shaping of epitranscriptome across multiple species - Nature Communications Nanopore direct RNA sequencing is promising for epitranscriptome study but remains limited in single-molecule resolution. Here, the authors develop SingleMod, a tool for accurate single-molecule m6A…

Single-molecule direct RNA sequencing reveals the shaping of epitranscriptome across multiple species. #DirectRNAseq #Epitranscriptomics #SingleMoleculeSequencing #NanoporeSequencing
@nanoporetech.com‬ @natcomms.nature.com‬
www.nature.com/articles/s41...

An RNA transmethylation pathway governs kidney nephrogenic potential - Nature Communications The mechanisms governing kidney nephrogenic capacity are incompletely understood. Here, the authors reveal that METTL3-dependent RNA transmethylation is both necessary and sufficient to promote nephro...

Thrilled to share our new work in Nature Communications!

We discovered how methionine → SAM → METTL3 → RNA methylation axis guides kidney development, especially nephron progenitor differentiation. #Nephrology #Epitranscriptomics

Here’s a quick breakdown

www.nature.com/articles/s41...

Our work expands METTL3’s function beyond RNA methylation, highlighting a non-catalytic mechanism in intracellular vesicle trafficking. Check it out!🎉
#biorxiv #preprint #METTL3 #RNA #Epitranscriptomics